Stach, James - Newcastle University

研究领域

Principal research interests include the ecology of marine actinomycetes, (diversity, abundance and biogeography), novel natural products from marine actinomycetes, the application of peptide nucleic acids in species-specific bactericide and the development of antisense-based antibacterial screens

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Villapún VM, Zhang H, Howden C, Cheung Chow L, Esat F, Pérez P, Sort J, Bull S, Stach J, González S. Antimicrobial and wear performance of Cu-Zr-Al metallic glass composites. Materials and Design 2016, epub ahead of print. Chindera K, Mahalo M, Sharma A, Horsley H, Kloc-Muniak K, Kamaruzzamabn N, Kumar S, McFarlane A, Stach J, Bentin T, Good L. The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes. Nature Scientific Reports 2016, 6, 23121. Byrne MJ, Lees NR, Han LC, van der Kamp MW, Mulholland AJ, Stach JEM, Willis CL, Race PR. The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail. Journal of the American Chemical Society 2016, 138(19), 6095-6098. Goh S, Stach JEM, Good L. Antisense effects of PNAs in bacteria. Methods in Molecular Biology 2014, 1050, 223-236. Mondhe M, Chessher A, Goh S, Good L, Stach JEM. Species-selective killing of bacteria by antimicrobial peptide-PNAs. PLoS ONE 2014, 9(2), e89082. Goodfellow M, Brown R, Ahmed L, Pathom-aree W, Bull AT, Jones AL, Stach JEM, Zucchi TD, Zhang LX, Wang J. Verrucosispora fiedleri sp nov., an actinomycete isolated from a fjord sediment which synthesizes proximicins. Antonie van Leeuwenhoek 2013, 103(3), 493-502. Uguru GC, Mondhe M, Goh S, Hesketh A, Bibb MJ, Good L, Stach JEM. Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2). PLoS ONE 2013, 8(6), e67509. Prieto-Davo A, Villarreal-Gomez LJ, Forschner-Dancause S, Bull AT, Stach JEM, Smith DC, Rowley DC, Jensen PR. Targeted search for actinomycetes from nearshore and deep-sea marine sediments. FEMS Microbiology Ecology 2013, 84(3), 510-518. Ghosal A, Vitali A, Stach JEM, Nielsen PE. Role of SbmA in the Uptake of Peptide Nucleic Acid (PNA)-Peptide Conjugates in E. coli . ACS Chemical Biology 2012, 8(2), 360-367. Goodfellow M, Stach JEM, Brown R, Bonda ANV, Jones AL, Mexson J, Fiedler HP, Zucchi TD, Bull AT. Verrucosispora maris sp nov., a novel deep-sea actinomycete isolated from a marine sediment which produces abyssomicins. Antonie van Leeuwenhoek 2012, 101(1), 185-193. Gottardi EM, Krawczyk JM, von Suchodoletz H, Schadt S, Mühlenweg A, Uguru GC, Pelzer S, Fiedler H-P, Bibb MJ, Stach JEM, Süssmuth RD. Abyssomicin Biosynthesis: Formation of an Unusual Polyketide, Antibiotic-Feeding Studies and Genetic Analysis. ChemBioChem 2011, 12(9), 1401-1410. Roh H, Uguru GC, Ko HJ, Kim S, Kim B-Y, Goodfellow M, Bull AT, Kim KH, Bibb MJ, Choi IG, Stach JEM. Genome Sequence of the Abyssomicin- and Proximicin-Producing Marine Actinomycete Verrucosispora maris AB-18-032. Journal of Bacteriology 2011, 193(13), 3391-3392. Good L, Stach JEM. Synthetic RNA silencing in bacteria - antimicrobial discovery and resistance breaking. FRONTIERS IN MICROBIOLOGY 2011, 2. Stach J. Antimicrobials: Treasures from the oceans. Microbiology Today 2010, 37(2), 104-109. Boberek JM, Stach JEM, Good L. Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine. PLoS One 2010, 5(10), e13745. Hohmann C, Schneider K, Bruntner C, Irran E, Nicholson G, Bull AT, Jones AL, Brown R, Stach JEM, Goodfellow M, Beil W, Kramer M, Imhoff JF, Sussmuth RD, Fiedler HP. Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp NTK 937. Journal of Antibiotics 2009, 62(2), 99-104. Goh S, Boberek J, Nakashima N, Stach J, Good L. Concurrent Growth Rate and Transcript Analyses Reveal Essential Gene Stringency in Escherichia coli. PLoS One 2009, 4(6), e6061. Maldonado LA, Stach JEM, Ward AC, Bull AT, Goodfellow M. Characterisation of micromonosporae from aquatic environments using molecular taxonomic methods. Antonie van Leeuwenhoek 2008, 94(2), 289-298. Antony-Babu S, Stach JEM, Goodfellow M. Genetic and phenotypic evidence for Streptomyces griseus ecovars isolated from a beach and dune sand system. Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology 2008, 94(1), 63-74. Bull AT, Stach JEM. Marine actinobacteria: new opportunities for natural product search and discovery. Trends in Microbiology 2007, 15(11), 491-499. Herrera A, Hery M, Stach JEM, Jaffre T, Normand P, Navarro E. Species richness and phylogenetic diversity comparisons of soil microbial communities affected by nickel-mining and revegetation efforts in New Caledonia. European Journal of Soil Biology 2007, 43(2), 130-139. Maldonado LA, Stach JEM, Pathom-Aree W, Ward AC, Bull AT, Goodfellow M. Diversity of cultivable actinobacteria in geographically widespread marine sediments. Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology 2005, 87(1), 11-18. Stach JEM, Bull AT. Estimating and comparing the diversity of marine actinobacteria. Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology 2005, 87(1), 3-9. Bringmann G, Lang G, Maksimenka K, Hamm A, Gulder TAM, Dieter A, Bull AT, Stach JEM, Kocher N, Muller WEG, Fiedler H-P. Gephyromycin, the first bridged angucyclinone, from Streptomyces griseus strain NTK 14. Phytochemistry 2005, 66(11), 1366-1373. Bull AT, Stach JEM, Ward AC, Goodfellow M. Marine actinobacteria: Perspectives, challenges, future directions. Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology 2005, 87(1), 65-79.