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个人简介

Studied chemistry and physics at TU Berlin and Tübingen 1978 Ph.D. in physical chemistry, LMU Munich 1979-1980 Postdoctoral research, IBM Laboratories San Jose, California/USA 1982 Habilitation, LMU Munich 1981-1983 Teaching and Research Assistant

研究领域

Imaging, spectroscopy and manipulation of single molecules in Nano- and BioSciences Fluorescence Live Cell Imaging, Single Virus Tracing and Force Spectroscopy Dynamics of single molecules in nanoporous systems

近期论文

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Kos P., Lächelt U., Herrmann A., Mickler F.M., Döblinger M., He D., Krhač Levačić A., Morys S., Bräuchle C., Wagner E. Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer Nanoscale 7 (2015), 5350 Link Prescher J., Baumgärtel V., Ivanchenko S., Torrano A.A., Bräuchle C., Müller B., Lamb D.C. Super-Resolution Imaging of ESCRT-proteins at HIV-1 Assembly Sites PLoS Pathogens (2015), DOI:10.1371/journal.ppat.1004677 Link Pavlichenko I., Broda E., Fukuda Y., Szendrei K., Hatz A.K., Scarpa G., Lugli P., Bräuchle C., Lotsch B.V. Bringing One-Dimensional Photonic Crystals to a New Light: An Electrophotonic Platform for Chemical Mass Transport Visualisation and Cell Monitoring Materials Horizons (2015), accepted Link Front cover picture will be published in Materials Horizons, April 2015 Brunner K., Harder J., Halbach T., Willibald J., Spada F., Gnerlich F., Sparrer K., Beil A., Möckl L., Bräuchle C., Conzelmann K.-K., Carell T.* Cell-Penetrating and Neurotargeting Dendritic siRNA Nanostructures Angew. Chem. Int. Ed. 53(51) (2015), 1946. Link Dendritische Nanostrukturen zur rezeptorvermittelten Aufnahme von siRNA in neurale Zellen Angew. Chem. 126(51) (2015), 1968. Link Strobl F.G., Breyer D., Link P., Torrano A.A., Bräuchle C., Schneider M.F., Wixforth A. A surface acoustic wave-driven micropump for particle uptake investigation under physiological flow conditions in very small volumes Beilstein Journal of Nanotechnology 6 (2015), 414. Link Strobl F.G., Seitz F., Westerhausen C., Reller A., Torrano A.A., Bräuchle C., Wixforth A., Schneider, M.F. Intake of silica nanoparticles by giant lipid vesicles: influence of particle size and thermodynamic membrane state Beilstein Journal of Nanotechnology 5 (2014), 2468. Link Möckl L., Lamb D.C., Bräuchle C. Super-resolved Fluorescence Microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner Angew. Chem. Int. Ed. 53(51) (2014), 13972. Link Superhochauflösende Mikroskopie: Nobelpreis in Chemie 2014 fü r Eric Betzig, Stefan Hell und William E. Moerner Angew. Chem. 126(51) (2014), 14192. Link Davies M., Rühle B., Li C., Müllen K., Bein T.*, Bräuchle C.* Insights into Nanoscale Electrophoresis of Single Dye Molecules in Highly Oriented Mesoporous Silica Channels The Journal of Physical Chemistry C 118(41) (2014), 24013. Link Torrano A.A., Bräuchle C. Precise quantification of silica and ceria nanoparticle uptake revealed by 3D fluorescence microscopy Beilstein Journal of Nanotechnology 5 (2014), 1616. Link Argyo C., Weiss V., Bräuchle C., Bein T. Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery Chem. Mater. 26(1) (2014), 435. Link Lächelt U., Kos P., Mickler F.M., Herrmann A., Salcher E.E., Rödl W., Badgujar N., Bräuchle C., Wagner E. Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes Nanomedicine 10 (2014), 35. Link Strobel C., Torrano A.A., Herrmann R., Malissek M., Bräuchle C., Reller A., Treuel L., Hilger I. Effects of the physicochemical properties of titanium dioxide nanoparticles, commonly used as sun protection agents, on microvascular endothelial cells J. Nanopart. Res. 16:2130 (2014), 1. Link Torrano A.A., Blechinger J., Bräuchle C. Trafficking and Intracellular Distribution of Nanoparticles (Subchapter 6.4 of Chapter 6 "Biological Responses to Nanomaterials") In "Safety Aspects of Engineered Nanomaterials" Eds.: Luther W., Zweck A. Pan Stanford Publishing (2013), p. 157 Rühle B., Davies M., Bein T., Bräuchle C. Fluorescence Microscopy Studies of Porous Silica Materials Z. Naturforsch. 68b (2013), 423. Link Mackowiak S.A., Schmidt A., Weiss V., Argyo C., von Schirnding C., Bein T.*, Bräuchle C.* Targeted Drug Delivery in Cancer Cells with Red Light Photoactivated Mesoporous Silica Nanoparticles Nano Letters 13(6) (2013), 2576. Link see also LMU Press Release in English and German as well as NIM News Blechinger J., Bauer A.T., Torrano A.A., Gorzelanny C., Bräuchle C., Schneider S.W. Uptake Kinetics and Nanotoxicity of Silica Nanoparticles are Cell Type Dependent Small 9(23)(2013), 3970. Link Inside cover picture for Small December 2013, 9(23) Figuere from publication 305. Mackowiak S., Bräuchle C. Study of Single Molecule Dynamics in Mesoporous Systems, Glasses and Living Cells In "Nonequilibrium Statistical Physics of Small Systems: Fluctuation relations and beyond" Eds.: Klages R., Just W., Jarzynski C. Wiley VCH Weinheim (2013), p. 393. Torrano A.A., Blechinger J., Osseforth C., Argyo C., Reller A., Bein T., Michaelis J., Bräuchle C. A fast analysis method to quantify nanoparticle uptake on a single cell level Nanomedicine 8(11) (2013), 1815. Link

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