Graham, Alison - Newcastle University

研究领域

Research interests - pedagogy Using electronic marking to engage students with assessment and feedback. Investigating how students become “professionally literate” in their chosen field and how instructors can best support this transition. Research interests - microbiology Response of bacteria to environmental stresses: The effect of different metal ions on bacterial cells, particularly the response of E. coli to extremely low levels of zinc ions. The effect of shifting oxygen levels on bacterial cells.

近期论文

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Graham AI, Sanguinetti G, Bramall N, McLeod CW, Poole RK. Dynamics of a starvation-to-surfeit shift: A transcriptomic and modelling analysis of the bacterial response to zinc reveals transient behaviour of the Fur and SoxS regulators. Microbiology 2012, 158(1), 284-292. Holcombe M, Adra S, Bicak M, Chin S, Coakley S, Graham AI, Green J, Greenough C, Jackson D, Kiran M, Macneil S, Maleki-Dizaji A, McMinn P, Pogson M, Poole R, Qwarnstrom E, Ratnieks F, Rolfe MD, Smallwood R, Sun T, Worth D. Modelling complex biological systems using an agent-based approach. Integrative Biology 2012, 4(1), 53-64. Rolfe MD, TerBeek A, Graham AI, Trotter EW, Asif HMS, Sanguinetti G, deMattos JT, Poole RK, Green J. Transcript Profiling and Inference of Escherichia coli K-12 ArcA Activity across the Range of Physiologically Relevant Oxygen Concentrations. Journal of Biological Chemistry 2011, 286(12), 10147-10154. Graham AI, Hunt S, Stokes SL, Bramall N, Bunch J, Cox AG, McLeod CW, Poole RK. Severe Zinc Depletion of Escherichia coli: Roles for high affinity zinc binding by ZinT, zinc transport and zinc-independent proteins. Journal of Biological Chemistry 2009, 284(27), 18377-18389. Latimer J, Stokes SL, Graham AI, Bunch J, Jackson RJ, McLeod CW, Poole RK. A novel method for exploring elemental composition of microbial communities: Laser ablation-inductively coupled plasma-mass spectrometry of intact bacterial colonies. Journal of Microbiological Methods 2009, 79(3), 329-335. Maleki-Dizaji S, Holcombe M, Rolfe MD, Fisher P, Green J, Poole RK, Graham AI. A systematic approach to understanding Escherichia coli responses to oxygen: from microarray raw data to pathways and published abstracts. Online Journal of Bioinformatics 2009, 10(1), 51-59. Jackson RJ, Binet MRB, Lee LJ, Ma R, Graham AI, McLeod CW, Poole RK. Expression of the PitA phosphate/metal transporter of Escherichia coli is responsive to zinc and inorganic phosphate levels. FEMS Microbiology Letters 2008, 289(2), 219-224. Banci L, Bertini I, Cantini F, Ciofi-Baffoni S, Cavet JS, Dennison C, Graham AI, Harvie DR, Robinson NJ. NMR structural analysis of cadmium sensing by winged helix repressor CmtR. Journal of Biological Chemistry 2007, 282(41), 30181-30188. Cavet JS, Graham AI, Meng W, Robinson NJ. A cadmium-lead-sensing ArsR-SmtB repressor with novel sensory sites. Complementary metal discrimination by NmtR and CmtR in a common cytosol. Journal of Biological Chemistry 2003, 278(45), 44560-44566.