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2005-2006 Researcher in Catalyst Discovery & Development, Celtic Catalysts, Dublin, Ireland. 2003-2005 Marie Curie 'Development Host' Research Fellowship on Combinatorial Asymmetric Catalysis, School of Chemistry & Chemical Biology, UCD 2000-2003 Postdoctoral Research Fellow sponsored by BP Chemicals & Rhodia, School of Chemistry, University of Bristol with Prof. Paul Pringle

研究领域

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Fleming JT, Wills C, Waddell PG, Harrington RW, Higham LJ. A comparison of MOP-phosphonite ligands and their applications in Rh(I)- and Pd(II)-catalysed asymmetric transformations. Dalton Transactions 2016, 45(39), 15660-15670. Nigam S, Burke BP, Davies LH, Domarkas J, Wallis JF, Waddell PG, Waby JS, Benoit DM, Seymour AM, Cawthorne C, Higham LJ, Archibald SJ. Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells. Chemical Communications 2016, 52(44), 7114-7117. Davies LH, Wallis JF, Harrington RW, Waddell PG, Higham LJ. Air-stable fluorescent primary phosphine complexes of molybdenum and tungsten. Journal of Coordination Chemistry 2016, 69(11-13), 2069-2080. Walsh JPS, Bowling G, Ariciu A-M, Jailani NFM, Chilton NF, Waddell PG, Collison D, Tuna F, Higham LJ. Evidence of Slow Magnetic Relaxation in Co(AcO)2(py)2(H2O)2. Magnetochemistry 2016, 2(2), 23. Fleming JT, Ficks A, Waddell PG, Harrington RW, Higham LJ. The design of second generation MOP-phosphonites: efficient chiral hydrosilylation of functionalised styrenes. Dalton Transactions 2016, 45(5), 1886-1890. Bange CA, Ghebreab MB, Ficks A, Mucha NT, Higham LJ, Waterman R. Zirconium-catalyzed intermolecular hydrophosphination using a chiral, air-stable primary phosphine. Dalton Transactions 2016, 45(5), 1863-1867. Fleming JT, Higham LJ. Primary Phosphine Chemistry. Coordination Chemistry Reviews 2015, 297-298, 127-145. Fey N, Papadouli S, Pringle PG, Ficks A, Fleming JT, Higham LJ, Wallis JF, Carmichael D, Mézailles N, Müller C. Setting P-Donor Ligands into Context: An Application of the Ligand Knowledge Base (LKB) Approach. Phosphorus, Sulfur, and Silicon and the Related Elements 2015, 190(5-6), 706-714. Davies LH, Kasten BB, Benny PD, Arrowsmith RL, Ge H, Pascu SI, Botchway SW, Clegg W, Harrington RW, Higham LJ. Re and 99mTc complexes of BodP3 – multi-modality imaging probes. Chemical Communications 2014, 50(98), 15503-15505. Ficks A, Clegg W, Harrington RW, Higham LJ. Air-Stable Chiral Primary Phosphines: A Gateway to MOP Ligands with Previously Inaccessible Stereoelectronic Profiles. Organometallics 2014, 33(22), 6319-6329. Davies LH, Harrington RW, Clegg W, Higham LJ. BR2BodPR2: highly fluorescent alternatives to PPh3 and PhPCy2. Dalton Transactions 2014, 43(36), 13485-13499. Davies LH, Wallis JF, Probert MR, Higham LJ. Efficient Multigram Syntheses of Air-Stable, Fluorescent Primary Phosphines via Palladium-Catalyzed Phosphonylation of Aryl Bromides. Synthesis 2014, 46(19), 2622-2626. Davies LH, Higham LJ. Air-Stable, Fluorescent Primary Phosphines. In: Fairlamb,I.J.S;Lynam,J.M, ed. Organometallic Chemistry. Royal Sociey of Chemistry, 2014, pp.51-71. Ficks A, Harrington RW, Higham LJ. Chiral MOP-phosphonite ligands: synthesis, characterisation and interconversion of η1,η6-(σ-P, π-arene) chelated rhodium(I) complexes. Dalton Transactions 2013, 42(18), 6302-6305. Davies LH, Stewart B, Harrington RW, Clegg W, Higham LJ. Air-Stable, Highly Fluorescent Primary Phosphanes. Angewandte Chemie: International Edition 2012, 51(20), 4921-4924. Ficks A, Hiney RM, Harrington RW, Gilheany DG, Higham LJ. MOP-phosphonites: A novel ligand class for asymmetric catalysis. Dalton Transactions 2012, 41(12), 3515-3522. Laughlin FL, Rheingold AL, Deligonul N, Laughlin BJ, Smith RC, Higham LJ, Protasiewicz JD. Naphthoxaphospholes as examples of fluorescent phospha-acenes. Dalton Transactions 2012, 41(39), 12016-12022. Stewart B, Harriman A, Higham LJ. Air-stable chiral primary phosphines part (ii) predicting the air-stability of phosphines. In: Fairlamb, I.J.S., Lynam, J.M, ed. Specialist Periodical Reports: Organometallic Chemistry. London, UK: Royal Society of Chemistry, 2012, pp.36-47. Byrne PA, Higham LJ, McGovern P, Gilheany DG. Anomalous Z-isomer content in Wittig reaction products from keto-stabilised ylides with ortho-heteroatom substituted benzaldehydes. Tetrahedron Letters 2012, 53(49), 6701-6704. Higham LJ. The Primary Phosphine Renaissance. In: Peruzzini, M., Gonsalvi, L, ed. Phosphorus Compounds: Advanced Tools in Catalysis and Material Sciences. Germany: Springer, 2011. Stewart B, Harriman A, Higham LJ. Predicting the Air Stability of Phosphines. Organometallics 2011, 30(20), 5338-5343. Ficks A, Martinez-Botella I, Stewart B, Harrington RW, Clegg W, Higham LJ. Taming functionality: easy-to-handle chiral phosphiranes. Chemical Communications 2011, 47(29), 8274-8276. Clarke EF, Rafter E, Müller-Bunz H, Higham LJ, Gilheany DG. The Synthesis of P-Stereogenic MOP Analogues and their use in Rhodium Catalysed Asymmetric Addition. Journal of Organometallic Chemistry 2011, 696(23), 3608-3615. Hiney RM, Ficks A, Müller-Bunz H, Gilheany DG, Higham LJ. Air-stable Chiral Primary Phosphines: Part (i) Synthesis, Stability and Reactivity. In: Fairlamb, I.J.S., Lynam, J.M, ed. Specialist Periodical Reports: Organometallic Chemistry. London, UK: Royal Society of Chemistry, 2011, pp.27-45. Higham LJ, Muldoon J, Kelly PG, Corr DM, Muller-Bunz H, Gilheany DG. A re-evaluation of the electrophilic substitution reactions of the Ramirez ylide. Journal of Organic Chemistry 2007, 72(23), 8780-8785.

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