Hall, Michael - Newcastle University

个人简介

Qualifications DPhil, Linacre College, Oxford, 2003 MChem, Brasenose College, Oxford, 1999 Previous Positions CNRS Postdoctoral Research Fellow, ESPCI, Paris, 2006 Postdoctoral Research Assistant, CSCB, University College Dublin, 2003-2005

研究领域

Synthetic organic chemistry: Natural Products, Bioactive molecules, Microwave Chemistry

近期论文

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Baksh A, Kepplinger B, Isah H, Probert MR, Clegg W, Wills C, Goodfellow M, Errington J, Allenby N, Hall MJ. Production of 17-O-demethyl-geldanamycin, a cytotoxic ansamycin polyketide, by Streptomyces hygroscopicus DEM20745. Natural Product Research 2016, epub ahead of print. Alnoman RB, Rihn S, OConnor DC, Black FA, Costello B, Waddell PG, Clegg W, Peacock RD, Herrebout W, Knight JG, Hall MJ. Circularly Polarized Luminescence from Helically Chiral N,N,O,O-Boron Chelated Dipyrromethenes. Chemistry - A European Journal 2016, 22(1), 93-96. Abualnaja M, Waddell PG, Clegg W, Hall MJ. Synthesis of pentacyclic pyrrolo[3,4-a]carbazole-1,3(2H)-diones via an intermolecular Diels-Alder, intramolecular carbonyl-ene reaction strategy. Tetrahedron 2016, 72(38), 5798-5806. Cowell J, Abualnaja M, Morton S, Linder R, Buckingham F, Waddell PG, Probert MR, Hall MJ. Diastereoselective synthesis of functionalised carbazoles via a sequential Diels-Alder/ene reaction strategy. RSC Advances 2015, 5(21), 16125-16152. Cowell J, Harrington RW, Probert MR, Hall MJ. Enantioselective synthesis of functionalised tetrahydrocarbazoles via an organocatalysed Diels-Alder/ene reaction strategy. Tetrahedron: Asymmetry 2015, 26(20), 1189-1196. Essa AH, Lerrick RI, ?ift?i E, Harrington RW, Waddell PG, Clegg W, Hall MJ. Grignard-mediated reduction of 2,2,2-trichloro-1-arylethanones. Organic & Biomolecular Chemistry 2015, 13(20), 5793-5803. Oxley A, Berry P, Taylor GA, Cowell J, Hall MJ, Hesketh J, Lietz G, Boddy AV. An LC/MS/MS method for stable isotope dilution studies of β-carotene bioavailability, bioconversion and vitamin A status in humans. Journal of Lipid Research 2014, 55(2), 319-328. Lerrick RI, Winstanley TPL, Haggerty K, Wills C, Clegg W, Harrington RW, Bultinck P, Herrebout W, Benniston AC, Hall MJ. Axially Chiral BODIPYs. Chemical Communications 2014, 50(36), 4714-4716. Shields RC, Mokhtar N, Ford M, Hall MJ, Burgess JG, ElBadawey MR, Jakubovics NS. Efficacy of a Marine Bacterial Nuclease against Biofilm Forming Microorganisms Isolated from Chronic Rhinosinusitis. PLoS One 2013, 8(2), e55339. Essa AH, Lerrick RI, Tuna F, Harrington RW, Clegg W, Hall MJ. Reduction of 2,2,2-trichloro-1-arylethanones by RMgX: mechanistic investigation and the synthesis of substituted α,α-dichloroketones. Chemical Communications 2013, 49(27), 2756-2758. Watson LJ, Harrington RW, Clegg W, Hall MJ. Diastereoselective intermolecular ene reactions: synthesis of 4,5,6,7-tetrahydro-1H-benzo[d]imidazoles. Organic & Biomolecular Chemistry 2012, 10(33), 6649-6655. Grossi M, Palma A, McDonnell SO, Hall MJ, Rai DK, Muldoon J, O'Shea DF. Mechanistic Insight into Formation of Tetraarylazadipyrromethenes. Journal of Organic Chemistry 2012, 77(20), 9304–9312. Burgess JG, Hall MJ, Nijland R. Compounds and methods for biolfilm disruption and prevention. PCT/EP2011/052062, 2011, 11 February. Submitted. Druais V, Hall MJ, Corsi C, Wendeborn SV, Meyer C, Cossy J. A convergent approach toward phoslactomycins and leustroducsins. Tetrahedron 2010, 66(33), 6358-6375. Burgess JG, Hall MJ, Nijland R. Compounds and methods for biofilm disruption and prevention. GB1002396.8, 2010, 12 February. Nijland N, Hall MJ, Burgess JG. Dispersal of Biofilms by Secreted, Matrix Degrading, Bacterial DNase. PLoS One 2010, 5(12), e15668. Cotterill LJ, Harrington RW, Clegg W, Hall MJ. Thermal 1,3-Trityl Migrations in Diels-Alder Domino Reactions of 1-Trityl-4-vinyl-1H-imidazoles. Journal of Organic Chemistry 2010, 75(13), 4604-4607. Druais V, Hall MJ, Corsi C, Wendeborn SV, Meyer C, Cossy J. A Convergent Approach towards the C1–C11 Subunit of Phoslactomycins and Formal Synthesis of Phoslactomycin B. Organic Letters 2009, 11(4), 935–938. Robertson J, Hall MJ, Green SP. Stereospecific α-(methyl)allylation of hydroxyaldehydes by silatropic ene cyclisation. Tetrahedron 2009, 65(28), 5541-5551. Byrne AT, O'Connor AE, Hall M, Murtagh J, O'Neill K, Curran KM, Mongrain K, Rousseau JA, Lecomte R, McGee S, Callanan JJ, O'Shea DF, Gallagher WM. Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment. British Journal of Cancer 2009, 101(9), 1565-1573. Loudet A, Bandichhor R, Burgess K, Palma A, McDonnell SO, Hall MJ, O'Shea DF. B,O-Chelated Azadipyrromethenes as Near-IR Probes. Organic Letters 2008, 10(21), 4771-4774. Robertson J, Green SP, Hall MJ, Tyrrell AJ, Unsworth WP. Further studies on silatropic carbonyl ene cyclisations: β-crotyl(diphenyl)silyloxy aldehyde substrates; Synthesis of 2-deoxy-2-C-phenylhexoses. Organic and Biomolecular Chemistry 2008, 6(14), 2628-2635. Hall MJ, Allen LT, O'Shea DF. PET modulated fluorescent sensing from the BF2 chelated azadipyrromethene platform. Organic & Biomolecular Chemistry 2006, 4(5), 776-780. Hall MJ, McDonnell SO, Killoran J, O'Shea DF. A Modular Synthesis of Unsymmetrical Tetraarylazadipyrromethenes. The Journal of Organic Chemistry 2005, 70(14), 5571-5578. Gallagher WM, Allen LT, O'Shea C, Kenna T, Hall M, Gorman A, Killoran J, O'Shea DF. A Potent Non-Porphyrin Class of Photodynamic Therapeutic Agent: Cellular Localization, Potential and Influence on Hypoxia. British Journal of Cancer 2005, 92(9), 1702-1710.