Magoulas, Babis - Middlesex University - Department of Natural Sciences

个人简介

I obtained a BSc in Biochemistry with specialisation in Medicinal Chemistry from Concordia University, Montreal, in 1984. After working for several years as a research assistant in the field of Biotechnology, I entered graduate studies in Molecular Biology and was awarded a PhD degree from Ottawa University in 1992. My PhD thesis was on the molecular evolution of genetic regulatory mechanisms. I then completed a five year post-doctoral training in the field of Functional Genomics at the Imperial Cancer Research Fund (now known as Cancer Research UK), where I became a Marie Curie Fellow. In 1997, I joined the National Institute for Medical Research as a senior post-doctoral fellow in Molecular Neuroendocrinology. In 2000, I was appointed in a teaching and research position as a Lecturer in Neurosurgery at the School of Medicine and Dentistry in Queen Mary University of London. I taught medical courses at different levels, undergraduate and graduate, and my research was predominantly on mechanisms of inflammation and repair in the nervous system. I joined Middlesex University as a Senior Lecturer in 2014. I am involved in teaching and research in Biomedicine, and particular in the development of Neuroscience programmes.

研究领域

Neuronal Repair Neuro-Inflammation Cell Proliferation Molecular Imaging Functional Genetics

近期论文

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de Heredia, L.L., Magoulas, C. (2013) Lack of the transcription factor C/EBPd impairs the intrinsic capacity of peripheral neurons for regeneration. Exp. Neurol. 239, 148-157 de Heredia, L. L., Gengatharan, A., Foster, J., Mather, S., Magoulas, C. (2011) Bioluminescence imaging of the brain response to acute inflammation in living C/EBP reporter mice. Neurosci.Lett. 497, 134-130 Malysheva, M. V., Bulycheva, T. I., Deineko, N. L., Samoilova, R. S., Kaplanskaia, I. B., Magoulas, C., Zatsepina, O. V. (2010) The levels of key nucleolar proteins in the lymphoid cells of healthy individuals and patients with lymphoproliferative diseases. Klin.Lab Diagn. 23-27 Gushchina, S., Leinster, V., Wu, D., Jasim, A., Demestre, M., Lopez, d. H., Michael, G. J., Barker, P. A., Richardson, P. M., Magoulas, C. (2009) Observations on the function of nuclear factor kappa B (NF-kappaB) in the survival of adult primary sensory neurons after nerve injury. Mol.Cell.Neurosci. 40, 207-216 Miao, T., Wu, D., Zhang, Y., Bo, X., Xiao, F., Zhang, X., Magoulas, C., Subang, M. C., Wang, P., Richardson, P. M. (2008) SOCS3 suppresses AP-1 transcriptional activity in neuroblastoma cells through inhibition of c-Jun N-terminal kinase. Mol.Cell Neurosci. 37, 367-375 Wu, D., Zhang, Y., Bo, X., Huang, W., Xiao, F., Zhang, X., Miao, T., Magoulas, C., Subang, M. C., Richardson, P. M. (2007) Actions of neuropoietic cytokines and cyclic AMP in regenerative conditioning of rat primary sensory neurons. Exp.Neurol. 204, 66-76 Le Tissier, P. R., Carmignac, D. F., Lilley, S., Sesay, A. K., Phelps, C. J., Houston, P., Mathers, K., Magoulas, C., Ogden, D., Robinson, I. C. (2005) Hypothalamic growth hormone-releasing hormone (GHRH) deficiency: targeted ablation of GHRH neurons in mice using a viral ion channel transgene. Mol.Endocrinol. 19, 1251-1262 Polzikov, M., Zatsepina, O., Magoulas, C. (2005) Identification of an evolutionary conserved SURF-6 domain in a family of nucleolar proteins extending from human to yeast. Biochem.Biophys.Res.Commun. 327, 143-149 Liu, M., Liu, M. C., Magoulas, C., Priestley, J. V., Willmott, N. J. (2003) Versatile regulation of cytosolic Ca2+ by vanilloid receptor I in rat dorsal root ganglion neurons. J.Biol.Chem. 278, 5462-5472 Balthasar, N., Mery, P. F., Magoulas, C. B., Mathers, K. E., Martin, A., Mollard, P., Robinson, I. C. (2003) Growth hormone-releasing hormone (GHRH) neurons in GHRH-enhanced green fluorescent protein transgenic mice: a ventral hypothalamic network. Endocrinology 144, 2728-2740 Magoulas, C., McGuinness, L., Balthasar, N., Carmignac, D. F., Sesay, A. K., Mathers, K. E., Christian, H., Candeil, L., Bonnefont, X., Mollard, P., Robinson, I. C. (2000) A secreted fluorescent reporter targeted to pituitary growth hormone cells in transgenic mice. Endocrinology 141, 4681-4689 Magoulas, C., Fried, M. (1996) The Surf-6 gene of the mouse surfeit locus encodes a novel nucleolar protein. DNA Cell Biol. 15, 305-316 Magoulas, C., Bally-Cuif, L., Loverre-Chyurlia, A., Benkel, B., Hickey, D. (1993) A short 5'-flanking region mediates glucose repression of amylase gene expression in Drosophila melanogaster. Genetics 134, 507-515 Magoulas, C., Loverre-Chyurlia, A., Abukashawa, S., Bally-Cuif, L., Hickey, D. A. (1993) Functional conservation of a glucose-repressible amylase gene promoter from Drosophila virilis in Drosophila melanogaster. J.Mol.Evol. 36, 234-242