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个人简介

Highly Cited Researcher in Chemistry, Thomson Reuters Corporation (2014) Distinguished Visiting Scientist of the Institute of Materials Research and Engineering, Singapore (2014) International Award, The Society of Polymer Science, Japan (2014) President, International Scientific Committee of the Institute for Bioengineering of Catalonia, Spain (2014) Distinguished Visiting Professor of Biochemistry, University of Hong Kong (2014) Member, Scientific Advisory Board, Xeltis Corporation, Zurich, Switzerland (2013) Member, RIKEN Center for Emergent Matter Science Advisory Council, Japan (2013) Creation of the Samuel I. Stupp Prize in Nanotechnology by the Ministry of Science and Technology, Government of Costa Rica (2013) Honorary Doctorate from the University of Gothenburg, Sweden Medical School (2013) Australian Centre for Nanomedicine Annual Visiting Professorship (2013) International Scientific Advisory Board, Centre for Cooperative Research in Biomaterials-CIC biomaGUNE, Spain (2012) American Chemical Society Ronald Breslow Award for Achievement in Biomimetic Chemistry (2012) Member, National Academy of Engineering (2012) Member, Royal Spanish Academy of Pharmacy (2012) Thomson Reuters Top 100 Chemists for 2000-2010 (2011) Honorary Doctorate, National University of Costa Rica (2011) Michelin Chair, Ecole Supérieure de Physique et de Chimie, Paris (2010) Fellow, Materials Research Society (2009) Israel Pollack Distinguished Lecture Series Award, Technion-Israel Institute of Technology (2009) Distinguished Professorship, Eindhoven University of Technology (2009) Honorary Doctorate for Revolutionary Research in Complex Molecular Systems, Eindhoven University of Technology (2009) Honorary membership, Israel Chemical Society (2009) Member, World Premier International Program Advisory Committee to Advanced Institute for Materials Research, Japan Society for the Promotion of Science, Japan (2008) International Advisory Group, Swedish Government Program on Biomaterials, Gothenburg University (2008) Member, Scientific Advisory Board, University of Vienna (2006) American Chemical Society Award in Polymer Chemistry (2005) Merck-Karl Pfister Visiting Professorship, Massachusetts Institute of Technology (2004) Fellow, World Technology Network (2003) Member, Scientific Advisory Board, National University of Singapore (2003) Member, Baxter Scientific Advisory Board (2001) Member, Solid State Sciences Committee, National Academy of Sciences (2001) Materials Research Society Medal Award (2000) Member, Basic Energy Sciences Advisory Committee, Department of Energy (1999) Fellow of American Association for the Advancement of Science (1999) Elected member of American Academy of Arts and Sciences (1998) Humboldt Award for Senior U.S. Scientists (1997) Joliot Curie Professorship, Ecole Supérieure de Physique et de Chimie Industrielles (1997) Member, Materials Panel, Air Force Scientific Advisory Board (1995) U.S. Department of Energy Prize for Outstanding Scientific Accomplishment in Materials Chemistry (1991) Exclusive consultant to 3M Company (1987) Xerox Faculty Award for Excellence in Engineering Research (1985) 3M Young Faculty Award (1981)

研究领域

Research in the Stupp group integrates chemistry with materials science, biology, and medicine. The overarching interest of the group is the development of self-assembling organic materials, focusing on functions relevant to energy and medicine. In the area of energy science, the laboratory’s interests include, materials for solar photovoltaics, catalytic materials that can synthesize solar fuels, supramolecular ferroelectrics for non-volatile memories, and artificial muscle materials for inter-conversion of chemical and mechanical energy. In the area of medicine, the Stupp laboratory is interested in biomaterials for regenerative medicine of the brain, spinal cord, bone, cartilage and muscle, and also on targeted systemic drug delivery using nanostructures for cancer and cardiovascular applications. The organic structures of interest in both areas include, visible light absorbing chromophores, organometallic catalysts, electron donors and acceptors, DNA, peptides, glycopeptides, and polymers, among others. The group is organized into three sub-groups that meet weekly to discuss progress: Self-Assembly, Energy Materials, and Biomaterials. Research activities include, molecular synthesis, characterization of structure with a broad suite of microscopies and synchrotron x-ray scattering, measurement of materials properties, computer simulations, construction of solar cell and other electronic devices, molecular and cell biology, and in vivo studies of the efficacy of materials and nanostructures in biomedical applications.

近期论文

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Freeman, R.; Han, M.; Álvarez, Z.; Lewis, J. A.; Wester, J. R.; Stephanopoulos, N.; McClendon, M. T.; Lynsky, C.; Godbe, J. M.; Sangji, H.; Luijten E.; Stupp, S. I. "Reversible Self-Assembly of Superstructured Networks" Science 2018, 362 (6416), 808-813. Lau, G. C.; Sather, N. A.; Sai, H.; Waring, E. M.; Deiss-Yehiely, E.; Barreda. L.; Beeman, E. A.; Palmer, L. C.; Stupp, S. I. “Oriented Multiwalled Organic-Co(OH)2 Nanotubes for Energy Storage” Advanced Functional Materials 2018, 28(3), 1702320. Hendricks, M. P.; Sato, K.; Palmer, L. C.; Stupp, S. I. "Supramolecular Assembly of Peptide Amphiphiles" Accounts of Chemical Research 2017, 50(10), 2440-2448. Lee. S. S.; Fyrner, T.; Chen, F.; Alvarez, Z.; Sleep, E.; Chun, D. S.; Weiner, J. A.; Cook, R. W.; Freshman, R. D.; Schallmo, M. S.; Katchko, K. M.; Schneider, A. D.; Smith, J. T.; Yun, C.; Singh, G.; Hashmi, S. Z.; McClendon, M. T.; Yu, Z.; Stock, S. R.; Hsu, W. K.; Hsu, E. L.; Stupp, S. I. “Sulfated Glycopeptide Nanostructures for Multipotent Protein Activation” Nature Nanotechnology 2017, 12, 821-829. Freeman, R.; Stephanopoulos, N.; Alvarez, Z.; Lewis, J. A.; Sur, S.; Serrano, C. M.; Boekhoven, J.; Lee, S. S.; Stupp, S. I. “Instructing Cells with Programmable Peptide-DNA Hybrids” Nature Communications 2017, 8:15982 doi:10.1038/ncomms15982 Rubert Pérez, C. M.; Álvarez, Z.; Chen, F.; Aytun, T.; Stupp, S. I. "Mimicking the Bioactivity of Fibroblast Growth Factor-2 using Supramolecular Nanoribbons" ACS Biomater. Sci. Eng. 2017, 3(9), 2166-2175. ACS EDITORS’ CHOICE ARTICLE. Yu, Z.; Tantakitti, F.; Palmer, L.; Stupp, S. I. “Asymmetric Peptide Nanoribbons” Nano Letters 2016, 16(11), 6967-6974. Tantakitti, F.; Boekhoven, J.; Wang, X.; Kazantsev, R.; Yu, T.; Li, J.; Zhuang, E.; Zandi, R.; Ortony, J. H.; Newcomb, C. J.; Palmer, L. C.; Shekhawat, G. S.; Olvera de la Cruz, M.; Schatz, G. C.; Stupp, S. I. “Energy Landscapes and Function of Supramolecular Systems” Nature Materials 2016, 15(4), 469-476. Yu, Z; Tantakitti, F.; Yu, T.; Palmer, L. C.; Schatz, G. C.; Stupp, S. I. “Simultaneous Covalent and Non-Covalent Hybrid Polymerizations” Science 2016, 351(6272), 497-502. Weingarten, A. S.; Kazantsev, R. V.; Palmer, L. C.; Fairfield, D. J.; Koltonow, A. R.; Stupp, S. I. “Supramolecular Packing Controls H2 Photocatalysis in Chromophore Amphiphile Hydrogels” J. Am. Chem. Soc. 2015, 137(48), 15241-15246. ACS EDITORS’ CHOICE ARTICLE. Tayi, A. S.; Kaeser, A.; Matsumoto, M.; Aida, T.; Stupp, S. I. “Supramolecular Ferroelectrics” Nature Chemistry 2015, 7, 281-294. Stephanopoulos, N.; Freeman, R.; North, H. A.; Sur, S.; Jeong, S. J.; Tantakitti, F.; Kessler, J, A.; Stupp, S. I. “Bioactive DNA-Peptide Nanotubes Enhance the Differentiation of Neural Stem Cells Into Neurons” Nano Letters 2015, 15(1), 603-609. Lee, S. S.; Hsu, E. L.; Mendoza, M.; Ghodasra, J.; Nickoli, M. S.; Ashtekar, A.; Polavarapu, M.; Babu, J.; Riaz, R. M.; Nicolas, J. D.; Nelson, D.; Hashmi, S. Z.; Earhart, J. S.; Merk, B. R.; McKee, J. S.; Bairstow, S. F.; Shah, R. N.; Hsu, W. K.; Stupp, S. I. “Gel Scaffolds of BMP-2-binding Peptide Amphiphile Nanofibers for Spinal Arthrodesis” Advanced Healthcare Materials 2015, 4(1), 131-141. Weingarten, A. S.; Kazantsev, R. V.; Palmer, L. C.; McClendon, M.; Koltonow, A. R.; Samuel, A. P. S.; Kiebala, D. J.; Wasielewski, M. R.; Stupp, S. I. “Self-Assembling Hydrogel Scaffolds for Photocatalytic Hydrogen Production” Nature Chemistry 2014, 6, 964-970. Cui, H.; Cheetham, A. G.; Pashuck, E. T.; Stupp, S. I. “Amino Acid Sequence in Constitutionally Isomeric Tetrapeptide Amphiphiles Dictates Architecture of One-Dimensional Nanostructures” J. Am. Chem. Soc. 2014, 136(35), 12461-12468. Preslar, A. T.; Parigi, G.; McCLendon, M. T.; Sefick, S. S.; Moyer, T. J.; Haney, C. R.; Waters, E. A.; MacRenaris, K. W.; Luchinat, C.; Stupp, S. I.; Meade, T. J. “Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization In Vivo” ACS Nano 2014, 8(7), 7325-7332. Li, A.; Hokugo, A.; Yalom, A.; Berns, E. J.; Stephanopoulos, N.; McClendon, M. T.; Segovia, L. A.; Spigelman, I.; Stupp, S. I.; Jarrahy, R. “A Bioengineered Peripheral Nerve Construct Using Aligned Peptide Amphiphile Nanofibers” Biomaterials 2014, 35(31), 8780-8790. Ortony, J. H.; Newcomb, C.; Matson, J. B.; Palmer, L. C.; Doan, P. E.; Hoffman, B. M.; Stupp, S. I. “Internal Dynamics of a Supramolecular Nanofiber” Nature Materials 2014, 13, 812-816. Boekhoven, J.; Stupp, S. I. “Supramolecular Materials for Regenerative Medicine” Advanced Materials 2014, 26(11), 1642-1659. Newcomb, C. J.; Sur, S.; Ortony, J. H.; Lee, O-S.; Matson, J. B.; Boekhoven, J.; Yu, J-M.; Schatz, G. C.; Stupp, S. I. “Cell Death Versus Cell Survival Instructed by Supramolecular Cohesion of Nanostructures” Nature Communications 2014, 5(3321), 1-10.

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