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个人简介

We study how the brain integrates nutritional signals to regulate the reproductive axis, and how ovarian steroids (estrogen and progesterone) and insulin sensitivity influence brain activity associated with appetite regulation. The primary approach used in the laboratory is functional magnetic resonance imaging. This research will lead to a better understanding of appetite regulation and provide new avenues for the development of therapeutic options for the prevention/treatment of obesity and other eating disorders.

研究领域

Neuroendocrine regulation of the menstrual cycle and appetite Other Interests: Golf, gardening, boating, scuba diving

近期论文

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Van Vugt, DA, Krzemien, A, Alsaadi, H, Frank, TC, Reid, RL; Glucose-induced inhibition of the appetitive brain response to visual food cues in polycystic ovary syndrome patients. Brain Research; 1558: 44-56. Van Vugt, DA, Krzemien A, Alsaadi, H, Palerme, S, Reid, RL; Effect of insulin sensitivity on corticolimbic responses to food picture in women with polycystic ovary syndrome. Obesity 2013; 21: 1215-1222. Frank TC, Kim GL, Krzemien A, Van Vugt DA. Effect of menstrual cycle phase on corticolimbic brain activation by visual food cues. Brain Res 2010 Dec 2;1363:81-92. Van Vugt DA. Brain imaging studies of appetite in the context of obesity and the menstrual cycle. [Review] Hum Reprod Update 2010 May-Jun;16(3):276-92. Papadimitriou MA, Krzemien AA, Hahn PM, Van Vugt DA. Peptide YY(3-36)-induced inhibition of food intake in female monkeys. Brain Res 2007 Oct 17;1175:60-5. Lujan ME, Krzemien AA, Reid RL, Van Vugt DA. Developing a model of nutritional amenorrhea in rhesus monkeys. Endocrinology 2006 Jan;147(1):483-92.

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