Mueller, Christopher R - Queen's University - Department of Biomedical and Molecular Sciences

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Transcription factors in cancer Stress and Breast Cancer BRCA1 and Stem Cells Liquid Biopsy Circulating Tumour DNA

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Heather Ritter and Christopher R Mueller. Expression microarray identifies the unliganded glucocorticoid receptor as a regulator of gene expression in mammary epithelial cells. BMC Cancer. 2014 Aug 5; (14)275: 8807-8814 http://www.ncbi.nlm.nih.gov/pubmed/24755251 Kirsten Nesset, Ami Perri and Christopher R Mueller. The Glucocorticoid Receptor Gene Expression is Reduced and its Promoter is Hypermethylated in a Significant Percentage of Breast Tumours. Epigenetics. 2014 Jun 1;9(6): 851-859. http://www.ncbi.nlm.nih.gov/pubmed/24622770 Lixin Zhou, Marcia Graves, Gwen Macdonald, Jane Cipollone, Christopher R Mueller and Calvin Roskelley. Microenvironmental regulation of BRCA1 gene expression by c-Jun and Fra2 in pre-malignant human ovarian surface epithelial cells. Molecular Cancer Research. 2013 Mar;11(3):272-81 http://www.ncbi.nlm.nih.gov/pubmed/23339184 Heather Ritter, Lilia Antonova and Christopher Mueller. The unliganded glucocorticoid receptor positively regulates the tumour suppressor BRCA1 through GABP beta . Molecular Cancer Research 2012 Apr;10(4):558-69. http://www.ncbi.nlm.nih.gov/pubmed/22328717 Crista Thompson, Gwen MacDonald and Christopher R Mueller. Decreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1 containing complex. Molecular Cancer. 2011 May 24;10:62. http://www.ncbi.nlm.nih.gov/pubmed/21609478 Lilia Antonova, Kristan Aronson and Christopher Mueller. Stress and Breast Cancer: From Epidemiology to Molecular Biology. Breast Cancer Res. 2011 Apr 21;13(2):208 http://www.ncbi.nlm.nih.gov/pubmed/21575279 Lilia Antonova and Christopher R Mueller. Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: a possible molecular link between stress and breast cancer. Genes Chromosomes Cancer. 2008;47:341-352. http://www.ncbi.nlm.nih.gov/pubmed/18196591 Gwen MacDonald, Melissa Stramwasser and Christopher R Mueller. Characterization of a negative transcriptional element in the BRCA1 promoter. Breast Cancer Res. 2007;9:R49 http://www.ncbi.nlm.nih.gov/pubmed/17663789