个人简介

BS Textiles, Virginia Tech, 1973 PhD Chemistry, Virginia Tech, 1981 Post-doctoral Fellow, Department of Chemistry, Virginia Tech, 1981-1982 Research Scientist, Union Carbide Corp., 1982-1983 Manager, Materials Division, Thoratec Laboratories, 1983-1985 V.P., Research and Development, Thoratec Laboratories, 1985-1987 Research Scientist and Visiting Assistant Professor, Department of Chemistry, Virginia Tech, 1987-1988 Assistant Professor of Chemistry, Virginia Tech, 1988 - 1994 Associate Professor of Chemistry, Virginia Tech, 1994 - 2000 Professor of Chemistry, Virginia Tech, 2000 - present Director, Macromolecular Science and Engineering Education, Virginia Tech, 2000 - present

研究领域

Polymer/Organic

Dr. Riffle currently mentors a research group comprised of 12 Ph.D. students and 2 undergraduates. Of these, 9 are women and 4 are underrepresented minority students. Their focus is on the synthesis of functionalized homopolymers and block copolymers and their activity in metal complexation and particle formation; and in understanding structure-property relationships in thermoset copolymer networks.

近期论文

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S. Das, J. D. Goff, S. Williams, D. Salas-de la Cruz, J. S. Riffle, T. E. Long, K. I. Winey and G. L. Wilkes, Synthesis and Characterization of Novel Segmented Polyionenes Based on Polydimethylsiloxane Soft Segments, Journal of Macromolecular Science, 47(3), 215- 224 (2010). A. Ranjan, N. Pothayee, M. Seleem, N. Jain, N. Sriranganathan, J. S. Riffle and R. Kasimanickam, Drug delivery using novel nanoplexes against a Salmonella mouse infection model, Journal of Nanoparticle Research, 12, 905-914 (2010). Beth L. Caba, Qian Zhang, Matthew R. J. Carroll, Robert C. Woodward, Timothy G. St. Pierre, Elliot P. Gilbert, J. S. Riffle and Richey M. Davis, Nanostructure of PEO- polyurethane-PEO triblock copolymer micelles in water, Journal of Colloid and Interface Science, 344(1), 81-89 (2010). W. C. Miles, J. D. Goff, P. P. Huffstetler, O. T. Mefford, J. S. Riffle, R. M. Davis, The Design of Well-defined PDMS-Magnetite Complexes, Polymer, 51, 482-491 (2010). A. Ranjan, N. Pothayee, M. N. Seleem, R. D. Tyler, Jr., B. Brenseke, N. Sriranganathan, J. S. Riffle, R. Kasimanickam, Antibacterial efficacy of core-shell nanostructures encapsulating gentamicin against an in vivo intracellular Salmonella model, International Journal of Nanomedicine, 4, 289-297 (2009). W. C. Miles, J. D. Goff, P. P. Huffstetler, C. M. Reinholz, N. Pothayee, B. L. Caba, J. S. Boyd, R. M. Davis and J. S. Riffle, Synthesis and Colloidal Properties of Polyether- Magnetite Complexes in Water and Phosphate Buffered Saline, Langmuir, 25(2), 803-813 (2009). M. Seleem, N. Jain, N. Pothayee, A. Ranjan, J. S. Riffle and N. Sriranganathan, Targeting Brucella melitensis with polymeric nanoparticles containing streptomycin and doxycycline, FEMS Microbiology Letters, 294(1), 24-31 (2009). A. Ranjan, N. Pothayee, M. N. Seleem, N. Sriranganathan, R. Kasimanickam, M. Makris, J. S. Riffle, In-vitro trafficking and efficacy of core-shell nanostructures for treating intracellular Salmonella Infections, Antimicrobial Agents and Chemotherapy, 53(9), 3985- 3988 (2009). U. O. Häfeli, J. S. Riffle, L. Harris, A. Carmichael-Baranauskas, F. Mark, J. P. Dailey, D. Bardenstein, Cell Uptake and In Vitro Toxicity of Magnetic Nanoparticles Suitable for Drug Delivery, Molecular Pharmaceutics, 6(5), 1417-1428 (2009). J. D. Goff, P. P. Huffstetler, W. C. Miles, N. Pothayee, C. M. Reinholz, S. Ball, R. M. Davis, J. S. Riffle, Novel Phosphonate-functional Poly(ethylene oxide)-Magnetite Nanoparticles form Stable Colloidal Dispersions in Phosphate Buffered Saline, Chemistry of Materials, 21, 4784-4795 (2009).