Pryce, David Warren - Bangor University - School of Medical Sciences

个人简介

Current position Research Lecturer in Biomedical Sciences (immunology) Previous positions Other external positions previously held Gwynedd Haematology Fund Research Scientist NWCRF research Fellow, North West Cancer Research Fund Institute, Bangor University Visiting researcher, Marie Curie Research Institute, Oxted Educational Background Ph.D. in Molecular Genetics (BBSRC award) Bangor University BSc. (1st Hons) Biomolecular Sciences Bangor University Esteem Factors/ Awards External Examiner; PGT courses, University of Westminster (2012-2016) Bangor University Teaching Fellow Student-led teaching award Nominations: Supervisor of the Year (2014/15) Student-led teaching award Nominations: Teacher of the Year (2015/16) Teaching Director of Postgraduate Taught Degrees (SMS) Course Director: Medical Molecular Biology with Genetics MSc Offices held I am International, Erasmus & Study Abroad Co-ordinator for SMS Groups: SMS Academic Staff SMS Teaching Staff

研究领域

Our immune system plays a vital role in both destroying and limiting the development and progression of cancer. Cutting edge research into ‘immunoregulation’ is allowing the development of an exciting new range of ‘immunotherapies’, which aid and enhance the ability of our immune system to specifically destroy cancers. Unfortunately, however, via a process termed ‘immunoediting, a number of these can evolve to escape both immune system destruction and regulation. Research into the factors and potential targets involved in immunoediting is an extremely active area of Cancer immunotherapeutics. Intriguingly, a number of systemic autoimmune diseases are linked to either increased or decreased incidence of specific cancers. The research focus of Dr Pryce’s laboratory is aiming to characterise the roles of autoimmune disease associated ‘autoantigens’, in both cancer immunosurveilance and immunoediting, with the aim of developing novel targets and agents for enhanced cancer immunotherapies.

近期论文

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Wells, JL., Pryce, DW., Estreicher, A., Loidl, J., McFarlane, RJ., (2006) Linear element-independent meiotic recombination in Schizosaccharomyces pombe, Genetics, 174(3), 1105-14. Wells, JL., Pryce, DW., McFarlane, RJ., (2006) Homologous chromosome pairing in Schizosaccharomyces pombe, Yeast, 23(13), 977-989. Ilyushik, E., Pryce, DW., Walerych, D., Riddell, T., Wakeman, JA., Mcinerny, CJ., McFarlane, RJ., (2005) Psc3 cohesin of Schizosaccharomyces pombe: cell cycle analysis and identification of three distinct isoforms, Biological Chemistry, 386(7), 613-621. Pryce, DW., Lorenz, A., Smirnova, JB., Loidl, J., McFarlane, RJ., (2005) Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe, Genetics, 170(1), 95-106. Lorenz, A., Wells, JL., Pryce, DW., Novatchkova, M., Eisenhaber, F., McFarlane, RJ., Loidl, J., (2004) S-pombe meiotic linear elements contain proteins related to synaptonemal complex components, Journal of Cell Science, 117(15), 3343-3351. Doenhoff, MJ., Stanley, RG., Pryce, D., Curtis, RCH., Parry, H., Griffiths, K., Jackson, CL., (2003) Identification of a fibrinolytic enzyme in Schistosoma mansoni eggs and modulated blood fibrinogen metabolism in S. mansonz-infected mice, Parasitology, 126, 231-234.