Webster, Simon George - Bangor University - School of Biological Sciences

个人简介

Committees: SBS Research Committee SBS Board of Studies Groups: SBS Academic Staff SBS Teaching Staff

研究领域

Dr Simon Webster runs a well established group focussing on the study of crustacean endocrinology. The laboratory has an international reputation with regard to the study of neuropeptides involved in the control of moulting, reproduction and energy metabolism, using contemporary molecular techniques. A recent and exciting research theme in this group concerns the elucidation of the molecular mechanisms controlling the "biological clocks" in intertidal crustaceans, which drive daily and tidal rhythms of locomotor (swimming) activity.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Chung, JS., Webster, SG., (2008) Angiotensin-converting enzyme-like activity in crab gills and its putative role in degradation of crustacean hyperglycemic hormone, Archives of Insect Biochemistry and Physiology, 68(3), 171-180. Wilcockson, DC., Webster, SG., (2008) Identification and developmental expression of mRNAs encoding putative insect cuticle hardening hormone, bursicon in the green shore crab Carcinus maenas, General and Comparative Endocrinology, 156(1), 113-125. Chung, JS., Webster, SG., (2006) Binding sites of crustacean hyperglycemic hormone and its second messengers on gills and hindgut of the green shore crab, Carcinus maenas: A possible osmoregulatory role, General and Comparative Endocrinology, 147(2), 206-213. Chung, JS., Wilcockson, DC., Zmora, N., Zohar, Y., Dircksen, H., Webster, SG., (2006) Identification and developmental expression of mRNAs encoding crustacean cardioactive peptide (CCAP) in decapod crustaceans, Journal of Experimental Biology, 209(19), 3862-3872. Hsu, YWA., Messinger, DI., Chung, JS., Webster, SG., De la iglesia, HO., Christie, AE., (2006) Members of the crustacean hyperglycemic hormone (CHH) peptide family are differentially distributed both between and within the neuroendocrine organs of Cancer crabs: implications for differential release and pleiotropic function, Journal of Experimental Biology, 209(16), 3241-3256. Chung, JS., Webster, SG., (2005) Dynamics of in vivo release of molt-inhibiting hormone and crustacean hyperglycemic hormone in the shore crab, Carcinus maenas, Endocrinology, 146(12), 5545-5551. Coast, GM., Garside, CS., Webster, SG., Schegg, KM., Schooley, DA., (2005) Mosquito natriuretic peptide identified as a calcitonin-like diuretic hormone in Anopheles gambiae (Giles), Journal of Experimental Biology, 208(17), 3281-3291. Chung, JS., Webster, SG., (2004) Expression and release patterns of neuropeptides during embryonic development and hatching of the green shore crab, Carcinus maenas, Development, 131(19), 4751-4761. Okuno, A., Matsumoto, S., Chang, JS., Webster, S., (2004) CDNA cloning of a vasa-like gene of the green shore crab, Carcinus maenas, Zoological Science, 21(12), 1295-1296, Chung, JS., Webster, SG., (2003) Moult cycle-related changes in biological activity of moult-inhibiting hormone (MIH) and crustacean hyperglycaemic hormone (CHH) in the crab, Carcinus maenasi - From target to transcript, European Journal of Biochemistry, 270(15), 3280-3288. Ruddell, CJ., Wainwright, G., Geffen, A., White, MRH., Webster, SG., Rees, HH., (2003) Cloning, characterization, and developmental expression of a putative farnesoic acid O-methyl transferase in the female edible crab Cancer pagurus, Biological Bulletin, 205(3), 308-318. Wilcockson, DC., Chung, JS., Webster, SG., (2002) Is crustacean hyperglycaemic hormone precursor-related peptide a circulating neurohormone in crabs?, Cell and Tissue Research, 307(1), 129-138. Coast, GM., Webster, SG., Schegg, KM., Tobe, SS., Schooley, DA., (2001) The Drosophila melanogaster homologue of an insect calcitonin- like diuretic peptide stimulates V-ATPase activity in fruit fly Malpighian tubules, Journal of Experimental Biology, 204(10), 1795-1804. Dircksen, H., Bocking, D., Heyn, U., Mandel, C., Chung, JS., Baggerman, G., Verhaert, P., Daufeldt, S., Plosch, T., Jaros, PP., Waelkens, E., Keller, R., Webster, SG., (2001) Crustacean hyperglycaemic hormone (CHH)-like peptides and CHH- precursor-related peptides from pericardial organ neurosecretory cells in the shore crab, Carcinus maenas, are putatively spliced and modified products of multiple genes, Biochemical Journal, 356, 159-170. Lu, WQ., Wainwright, G., Olohan, LA., Webster, SG., Rees, HH., Turner, PC., (2001) Characterization of cDNA encoding molt-inhibiting hormone of the crab, Cancer pagurus; expression of MIH in non-X-organ tissues, Gene, 278(1-2), 149-159. Lu, WQ., Wainwright, G., Webster, SG., Rees, HH., Turner, PC., (2000) Clustering of mandibular organ-inhibiting hormone and moult- inhibiting hormone genes in the crab, Cancer pagurus, and implications for regulation of expression, Gene, 253(2), 197-207. Phlippen, MK., Webster, SG., Chung, JS., Dircksen, H., (2000) Ecdysis of decapod crustaceans is associated with a dramatic release of crustacean cardioactive peptide into the haemolymph, Journal of Experimental Biology, 203(3), 521-536. Webster, SG., Dircksen, H., Chung, JS., (2000) Endocrine cells in the gut of the shore crab Carcinus maenas immunoreactive to crustacean hyperglycaemic hormone and its precursor-related peptide, Cell and Tissue Research, 300(1), 193-205. Chung, JS., Dircksen, H., Webster, SG., (1999) A remarkable, precisely timed release of hyperglycemic hormone from endocrine cells in the gut is associated with ecdysis in the crab Carcinus maenas, Proceedings of the National Academy of Sciences of the United States of America, 96(23), 13103-13107. Tang, CH., Lu, WQ., Wainwright, G., Webster, SG., Rees, HH., Turner, PC., (1999) Molecular characterization and expression of mandibular organ- inhibiting hormone, a recently discovered neuropeptide involved in the regulation of growth and reproduction in the crab Cancer pagurus, Biochemical Journal, 343, 355-360. Wainwright, G., Webster, SG., Rees, HH., (1999) Involvement of adenosine cyclic-3 ',5 '-monophosphate in the signal transduction pathway of mandibular organ-inhibiting hormone of the edible crab, Cancer pagurus, Molecular and Cellular Endocrinology, 154(1-2), 55-62. Chung, JS., Wilkinson, MC., Webster, SG., (1998) Amino acid sequences of both isoforms of crustacean hyperglycemic hormone (CHH) and corresponding precursor-related peptide in Cancer pagurus, Regulatory Peptides, 77(1-3), 17-24. Wainwright, G., Webster, SG., Rees, HH., (1998) Neuropeptide regulation of biosynthesis of the juvenoid, methyl farnesoate, in the edible crab, Cancer pagurus, Biochemical Journal, 334, 651-657. Webster, SG., (1998) Peptidergic neurons in barnacles: An immunohistochemical study using antisera raised against crustacean neuropeptides, Biological Bulletin, 195(3), 282-289.