Nigam, Yamni - Swansea University - College of Human and Health Sciences

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Yamni is an Associate Professor in Biomedical Science at the College of Human and Health Sciences at Swansea University. She lectures in anatomy, physiology and pathophysiology. Her specialist teaching subjects include digestion, blood, immunology, microbiology, parasitology and wounds (infection and healing). Her research career, investigating the immune system of insects and invertebrates, commenced with her doctorate at Swansea University and now spans over 25 years. Her post-doctoral experience includes a period of time spent at Fundaco Oswaldo Cruz, Rio de Janeiro, Brazil, researching immune defences in insects that cause Chagas’ Disease. In 2001, she set up the Swansea Maggot Research Group, which focuses on the medicinal maggot, Lucilia sericata, and the molecules involved in larval therapy. She and her team have undertaken numerous investigations, and published their findings primarily on the antimicrobial activity of larval secretions, and wound healing molecules associated with this insect. In addition, she is investigating the presence of antimicrobial and haemostatic factors in other invertebrates. She is a member of the Welsh Wound Network group, set up through the Welsh Assembly in 2007, and has recently been awarded a grant from the Welsh Government to fund her investigations into the development of a new antibiotic from larval secretions. In April 2014, Yamni was selected as an elected participant of the elite Welsh Crucible Programme, promoting the development of future Research Leaders in Wales. Yamni is an Athena Swan Champion. She is also a member of the British Society for Parasitology and an Elected Fellow of the Royal Entomological Society. She is a trained STEM Ambassador, delivering interactive sessions on Microbiology and entomology to pupils at local schools. Areas of Expertise larval therapy antimicrobial factors wound healing invertebrate immunology

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Nigam, Y. (2016). Advances in Myiasis Treatment. Health Care: Current Reviews 2016, 4(1) https://cronfa.swan.ac.uk/Record/cronfa27247 doi:10.4172/2375-4273.1000161 Nigam, Y. & Morgan, C. (2015). Does maggot therapy promote wound healing? The clinical and cellular evidence. Journal of the European Academy of Dermatology and Venereology https://cronfa.swan.ac.uk/Record/cronfa25452 doi:10.1111/jdv.13534 Evans, R., Dudley, E. & Nigam, Y. (2015). Detection and partial characterization of antifungal bioactivity from the secretions of the medicinal maggot,Lucilia sericata. Wound Repair and Regeneration 23(3), 361-368. https://cronfa.swan.ac.uk/Record/cronfa21311 doi:10.1111/wrr.12287 Wilson, M., Nigam, Y., Jung, W., Knight, J. & Pritchard, D. (2015). The impacts of larval density and protease inhibition on feeding in medicinal larvae of the greenbottle fly Lucilia sericata. Medical and Veterinary Entomology https://cronfa.swan.ac.uk/Record/cronfa23780 doi:10.1111/mve.12138 Pritchard, D., Cerovsky, V., Nigam, Y. & et, a. (2015). TIME management by medicinal larvae. international wound journal https://cronfa.swan.ac.uk/Record/cronfa23779 doi:10.1111/iwj.12457 Pritchard, D. & Nigam, Y. (2013). Maximising the Secondary Beneficial Effects of Larval Debridement Therapy. Journal of Wound Care 22(11), 610-616. https://cronfa.swan.ac.uk/Record/cronfa16550 Cazander, G. Pritchard, D. Nigam, Y. Jung, W. & Nibbering, P. (2013). Multiple actions ofLucilia sericatalarvae in hard-to-heal wounds. BioEssays 35(12), 1083-1092. https://cronfa.swan.ac.uk/Record/cronfa16551 doi:10.1002/bies.201300071 Brimson, C. & Nigam, Y. (2013). The role of oxygen-associated therapies for the healing of chronic wounds, particularly in patients with diabetes. Journal of the European Academy of Dermatology and Venereology 27(4), 411-418. https://cronfa.swan.ac.uk/Record/cronfa12256 doi:10.1111/j.1468-3083.2012.04650.x Morgan, C. & Nigam, Y. (2013). Naturally derived factors and their role in the promotion of angiogenesis for the healing of chronic wounds. Angiogenesis 16(3), 493-502. https://cronfa.swan.ac.uk/Record/cronfa14699 doi:10.1007/s10456-013-9341-1 Harris, L. Nigam, Y. Sawyer, J. Mack, D. & Pritchard, D. (2013). Lucilia sericata Chymotrypsin Disrupts Protein Adhesin-Mediated Staphylococcal Biofilm Formation. Applied and Environmental Microbiology 79(4), 1393-1395. https://cronfa.swan.ac.uk/Record/cronfa14701 doi:10.1128/AEM.03689-12 Nigam, Y. (2013). Evidence for larval debridement therapy in wound cleansing and healing. Wounds UK Supplement: LDT:an economic, scientific and clinical evaluation 9(4), 12-16. https://cronfa.swan.ac.uk/Record/cronfa16549 Nigam, Y. Knight, J. Bhattacharya, S. & Bayer, A. (2012). Physiological Changes Associated with Aging and Immobility. Journal of Aging Research 2012, 1 https://cronfa.swan.ac.uk/Record/cronfa10818 doi:10.1155/2012/468469 Bexfield, A. Bond, A. Morgan, C. Wagstaff, J. Newton, R. Ratcliffe, N. Dudley, E. & Nigam, Y. (2010). Amino acid derivatives fromLucilia sericataexcretions/secretions may contribute to the beneficial effects of maggot therapy via increased angiogenesis. British Journal of Dermatology 162(3), 554-562. https://cronfa.swan.ac.uk/Record/cronfa8919 doi:10.1111/j.1365-2133.2009.09530.x