D'Sa, Raechelle - University of Liverpool

个人简介

Raechelle completed her BSc (Honours) in Chemistry and Biology at the University of Toronto. She then went on to undertake a Masters in Organic Chemistry at the Johns Hopkins University. This was followed by by a short break in academia, during which time she obtained industrial experience as a research chemist at a contract research company (TDA Research, Inc., Golden, CO, USA). She subsequently came to the UK to obtain her PhD in Biomaterials. Her dissertation was on the surface modification of medically relevant polymers for increased biocompatibility at the University of Ulster. She went on to carry out postdoctoral research focusing on the study of mammalian and bacterial cells with surfaces structured at the nanometer scale. She joined the University of Liverpool as a lecturer in July 2013. Institute of Physics and Engineering in Medicine Bursary (IPEM 2011) Andrew Carnegie Research Fund (IOM3 2011) Royal Society of Chemistry Travel Bursary (RSC 2011) Best Poster Presentation at Nano-Molecular Analysis for Emerging Technologies IV Conference (NPL 2010) Invited Departmental Seminar at York University, Canada (Invitation to Speak, York University, Canada 2010) Best Oral Presentation at Northern Ireland Biomedical Engineering Society meeting (Northern Ireland Biomedical Engineering Society 2009) UKRC Technical Training Grant (UKRC 2009) Best Thesis Award-University of Ulster (University of Ulster 2009) Best Poster Presentation-Institute of Biology (Institute of Biology 2007) Best Poster Prize-Faculty of Engineering, University of Ulster (Faculty of Engineering, University of Ulster 2007) DePuy Student Award-NIBES meeting (NIBES 2006) Buhle Endowment Fellowship (Johns Hopkins University 2002) Arthur D. Chambers Memorial Fellowship (Johns Hopkins University 2002) Athena Swan Self Assessment Team LivWISE Steering Group Committee Student Without Borders Coordinator Ethics Committee Safety Champion-Biomedical Engineering Labs

研究领域

Raechelle joined the University of Liverpool in July 2013. Her field of expertise is in Biointerface Engineering. A key theme of her research career to date has been to design biomimetic interfaces for both fundamental science and medical device applications. Her research involves incorporating engineering, materials and analytical chemistry to create novel interfaces capable controlling biological response. Specifically, research has focused surface modification of polymers using plasma treatment, plasma polymerisation and grafting of polymers (polysaccharides, polyethylene glycol (PEG)) to create protein, cell and bacterial resistant surfaces. Furthermore she has used extremely sensitive surface analytical techniques (XPS and ToF-SIMS) to understand the role of surface chemistry in biointerfacial science.

近期论文

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Human Fetal Osteoblast Response on Poly(Methyl Methacrylate)/Polystyrene Demixed Thin Film Blends: Surface Chemistry Vs Topography Effects. Human mesenchymal stem cell response to poly(epsilon-caprolactone/poly(methyl methacrylate) demixed thin films Protein, cell and bacterial response to atmospheric pressure plasma grafted hyaluronic acid on poly(methylmethacrylate). Solar Photocatalytic Disinfection of Water using Titanium Dioxide Graphene Composites Atmospheric pressure plasma induced grafting of poly(ethylene glycol) onto silicone elastomers for controlling biological response Controlling the size and size distribution of gold nanoparticles: A design of experiment study The role of enamel proteins in protecting mature human enamel against acidic environments: A double layer force spectroscopy study Inhibition of lens epithelial cell growth via immobilisation of hyaluronic acid on atmospheric pressure plasma modified polystyrene Lens epithelial cell response to atmospheric pressure plasma modified poly(methylmethacrylate) surfaces Nanoscale surface modifications to control capillary flow characteristics in PMMA microfluidic devices Photolithographic structuring of stretchable conductors and sub-kPa pressure sensors Protein adhesion and cell response on atmospheric pressure dielectric barrier discharge-modified polymer surfaces Structural and surface energy analysis of nitrogenated ta-C films. Chemical grafting of poly(ethylene glycol) methyl ether methacrylate onto polymer surfaces by atmospheric pressure plasma processing Photochemistry of 1-(N, N-diethylamino) diazen-1-ium-1, 2-diolate: An experimental and computational investigation Preparation and reactivity of O 2-sulfonated diazeniumdiolates Controlled Photochemical Release of Nitric Oxide from O 2-Naphthylmethyl-and O 2-Naphthylallyl-Substituted Diazeniumdiolates Controlled photochemical release of nitric oxide from O2-benzyl substituted diazeniumdiolates Acidity constants and reactivities of the benzidine and N, N-dimethylbenzidine dications, the two electron oxidation intermediates of benzidine carcinogens Tautomers and conjugate base of the nitrenium ion derived from N-acetylbenzidine