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个人简介

I graduated with a degree in Chemistry from the University of Cambridge, and was then awarded a PhD in synthetic organic chemistry by the University of Nottingham. Since then, I have worked in biochemistry and molecular biology at the University of Leicester and the National Institutes of Health, MD, USA before coming to Liverpool as a lecturer in 1994. DNA topoisomerases, DNA topology and human health (Invitation to Speak, EMBO 2015) The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand brea (Invitation to Speak, Topo2011 2011) The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA breaks (Invitation to Speak, Kyoto, Japan 2010) Convincing first years that biology is a quantitative subject - a semester 1 maths module (Invitation to Speak, Higher Education Adademy 2010) School-based projects: student collaboration with secondary schools to develop lesson materials (Invitation to Speak, Higher Eduction Academy 2010) Within School of Biological Sciences: Chair of the Teaching Innovation Group Member of Learning and Teaching Group

近期论文

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DNA Topology (Book - 2005) The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks (Journal article - 2011) Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine (Journal article - 2012) How Do Type II Topoisomerases Use ATP Hydrolysis to Simplify DNA Topology beyond Equilibrium? Investigating the Relaxation Reaction of Nonsupercoiling Type II Topoisomerases (Journal article - 2009)

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