Antonyuk, Svetlana - University of Liverpool

个人简介

I have a background in biophysics and protein crystallography. In addition to X-ray crystallography I am interested in Neutron diffraction, which gives exceptional information on location of hydrogen atoms. My research interests include structure based drug design, transport and metabolism as well as the study of molecules and complexes involved in neurodegenerative diseases, malaria, toxoplasmosis, viral replication, liver/colon cancer, NO-signaling and the nitrogen cycle.

近期论文

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2016 A faulty interaction between SOD1 and hCCS in neurodegenerative disease (Journal article) Wright, G. S. A., Antonyuk, S. V., & Hasnain, S. S. (2016). A faulty interaction between SOD1 and hCCS in neurodegenerative disease. SCIENTIFIC REPORTS, 6. doi:10.1038/srep27691 DOI: 10.1038/srep27691 Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes (Journal article) Murray, B., Antonyuk, S. V., Marina, A., Lu, S. C., Mato, J. M., Hasnain, S. S., & Rojas, A. L. (2016). Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(8), 2104-2109. doi:10.1073/pnas.1510959113 DOI: 10.1073/pnas.1510959113 Fresh insight to functioning of selected enzymes of the nitrogen cycle (Journal article) Eady, R. R., Antonyuk, S. V., & Hasnain, S. S. (2016). Fresh insight to functioning of selected enzymes of the nitrogen cycle. CURRENT OPINION IN CHEMICAL BIOLOGY, 31, 103-112. doi:10.1016/j.cbpa.2016.02.009 DOI: 10.1016/j.cbpa.2016.02.009 New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections (Journal article) McPhillie, M., Zhou, Y., El Bissati, K., Dubey, J., Lorenzi, H., Capper, M., . . . McLeod, R. (2016). New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. SCIENTIFIC REPORTS, 6. doi:10.1038/srep29179 DOI: 10.1038/srep29179 Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal (Journal article) Horrell, S., Antonyuk, S. V., Eady, R. R., Hasnain, S. S., Hough, M. A., & Strange, R. W. (2016). Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. IUCRJ, 3, 271-281. doi:10.1107/S205225251600823X DOI: 10.1107/S205225251600823X 2015 Antimalarial 4(1H)-pyridones bind to the Q(i) site of cytochrome bc(1) (Journal article) Capper, M. J., O'Neill, P. M., Fisher, N., Strange, R. W., Moss, D., Ward, S. A., . . . Antonyuk, S. V. (2015). Antimalarial 4(1H)-pyridones bind to the Q(i) site of cytochrome bc(1). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(3), 755-760. doi:10.1073/pnas.1416611112