个人简介

I obtained a BSc in Biochemistry and Immunology at the University of Strathclyde followed by a PhD at the University of York working on the activity and inhibition of the microbial ribosomal cytotoxin, colicin E3. A collaboration during my PhD led me to the position as a Postdoctoral Research Scientist at the Universitaet Witten/Herdecke, Germany, where I worked on the inhibition of the 70S ribosome by the ribosomal ribonuclease, colicin E3. I then took a postion at the National Institute of Biological Standards and Control (NIBSC) as a Postdoctoral Research Scientist analysing novel vaccines for Health Care Associated Infections and Neonatal Infections. I started work as a lecturer at the University of Lincoln in November 2012. Department Responsibilities Within the department, I am responsible for teaching microbiology and immunology, running lectures, practical sessions and workshops. I am also the Student Engagement Champion. Subject Specialism Specialist in alternative antibiotics and vaccines. Qualifications PhD in Biology — University of York, 2005 BSc in Biochemistry and Immunology — University of Strathclyde, 2001 Professional Affiliations European Society of Clinical Microbiology and infectious Diseases Society for General Microbiology British Biophysical Society Biochemical Society

研究领域

Effect of n-butanol on the membranes of Clostridial bacteria — Awarded £5,000 by CBMNet NIBB in 2015

Alternative antimicrobials Bacteriocins Drug delivery and design Protein function

近期论文

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Papadakos, Grigorius and Sharma, Amit and Lancaster, Lorna and Bowen, Rebecca and Kaminska, Renata and Leech, Andrew P and Walker, Daniel and Redfield, Christina and Kleanthous, Colin (2015) Consequences of inducing intrinsic disorder in a high-affinity protein-protein interaction. Journal of the American Chemical Society, 137 (16). pp. 5252-5255. ISSN: 0002-7863 Lancaster, Lorna and Saydam, Manolya and Markey, Kevin and Ho, Mei and Mawas, Fatme (2011) Immunogenicity and physico-chemical characterisation of a candidate conjugate vaccine against group B streptococcus serotypes Ia, Ib and III. Vaccine, 29 (7). pp. 3213-3221. ISSN: 0264-410X Lancaster, Lorna and Markey, Kevin and Ho, Mei (2011) An assessment of the thermal stability of Clostridium difficile toxoid formulations. Human Vaccines, 7 (2). pp. 202-210. ISSN: 1554-8600 Lancaster, Lorna and Savelsbergh, Andreas and Kleanthous, Colin and Wintermeyer, Wolfgang and Rodnina, Marina (2008) Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes. Molecular Microbiology, 69 (2). pp. 390-401. ISSN: 0950-382X Lancaster, Lorna and Wintermeyer, Wolfgang and Rodnina, Marina (2007) Colicins and their potential in cancer treatment. Blood, Cells, Molecules and Diseases, 38 (1). pp. 15-18. ISSN: 1079-9796 Walker, Daniel and Lancaster, Lorna and James, Richard and Kleanthous, Colin (2004) Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3. Protein Science, 13 (6). pp. 1603-1611. ISSN: 0961-8368