Gutierrez, Humberto - University of Lincoln

个人简介

B. Sc in (Biomedical Research), National University of Mexico (UNAM), M.Sc (Biomedical Research), Ph.D. (Biomedical Sciences), Research Fellow. St. Andrews University,2000. Research Fellow, University of Edinburgh, 2001-2002. The Wellcome Trust´s Travelling Research Fellow University of Edinburgh, 2002-2003. Research Associate, Preclinical Veterinary Sciences,University of Edinburgh, 2003-2004. Research Associate, Cardiff School of Biosciences, Cardiff University, 2004-2010. Principal Investigator at the Institute of Cellular Physiology (UNAM, Mexico), 2010-2011. Senior Lecturer in Biomedical Sciences, School of Life Sciences, University of Lincoln, 2012- present. Department Responsibilities 1) Module Coordinator (Human Anatomy and Physiology) 2) Tutorials co-ordination 3) Teaching in cell biology, genetics, reproduction and development and human anatomy and physiology undergraduate modules. 3) Research on developmental neurobiology (http://hgutierrez.blogs.lincoln.ac.uk/) Subject Specialism Developmental Neurobiology, neuronal cell signalling, functional neurogenomics and evolution of brain complexity. Qualifications B. Sc in (Biomedical Research), M.Sc (Biomedical Research), Ph.D. (Biomedical Sciences), Awards 2000, National council of Science and Technology (CONACyT) research fellowship. 2002, Wellcome Trust Travelling Research Fellowship . 2010, CONACyT research Grant.

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Collins, Louise M. and Dal Bo, Giorgia and Calcagno, Mariangela and Monzón-Sandoval, Jimena and Sullivan, Aideen M. and Gutierrez, Humberto and Morari, Michele and O’Keeffe, Gerard W. (2016) Nociceptin/orphanin FQ inhibits the survival and axon growth of midbrain dopaminergic neurons through a p38-MAPK dependent mechanism. Molecular Neurobiology, 53 (10). pp. 7284-7297. ISSN: 0893-7648 Monzón-Sandoval, Jimena and Castillo-Morales, Atahualpa and Urrutia, Araxi O. and Gutierrez, Humberto (2016) Modular reorganization of the global network of gene regulatory interactions during perinatal human brain development.. BMC developmental biology, 16. pp. 13. ISSN: 1471-213X O’Keeffe, Gerard W. and Gutierrez, Humberto and Howard, Laura and Laurie, Christopher W. and Osorio, Catarina and Gavaldà, Núria and Wyatt, Sean L. and Davies, Alun M. (2016) Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation. Neural Development, 11 (1). ISSN: 1749-8104 Monzón-Sandoval, Jimena and Castillo-Morales, Atahualpa and Crampton, Sean and McKelvey, Laura and Nolan, Aoife and O’Keeffe, Gerard and Gutierrez, Humberto (2015) Modular and coordinated expression of immune system regulatory and signaling components in the developing and adult nervous system. Frontiers in Cellular Neuroscience, 9. ISSN: 1662-5102 Sheikh, Ahmad Hassan and Barry, Denis S, and Gutierrez, Humberto and Cryan, John F. and O'Keeffe, Gerard W. (2015) Cadaveric anatomy in the future of medical education: what is the surgeons view?. Anatomical Sciences Education, 9 (2). pp. 203-208. ISSN: 1935-9772 Nolan, Aoife M. and Collins, Louise M. and Wyatt, Sean L. and Gutierrez, Humberto and O'Keeffe, Gerard W. (2014) The neurite growth inhibitory effects of soluble TNFα on developing sympathetic neurons are dependent on developmental age. Differentiation, 88 (4-5). pp. 124-130. ISSN: 0301-4681 Togher, K. L. and O'Keeffe, M. M. and Khashan, A. S. and Gutierrez, Humberto and Kenny, L. C. and O'Keeffe, G. W. (2014) Epigenetic regulation of the placental HSD11B2 barrier and its role as a critical regulator of fetal development. Epigenetics, 9 (6). pp. 816-822. ISSN: 1559-2294 Castillo-Morales, Atahualpa and Monzon-Sandoval, Jimena and Urrutia, Araxi O. and Gutierrez, Humberto (2013) Increased brain size in mammals is associated with size variations in gene families with cell signalling, chemotaxis and immune-related functions. Proceedings of the Royal Society B: Biological Sciences, 281 (1775). ISSN: 0962-8452 Gutierrez, Humberto and Kisiswa, Lilian and O'Keeffe, Gerard W. and Smithen, Matthew J. and Wyatt, Sean and Davies, Alun M. (2013) Regulation of neurite growth by tumour necrosis superfamily member RANKL. Open biology, 3 (1). pp. 120150. ISSN: 2046-2441 McKelvey, Laura and Gutierrez, Humberto and Nocentini, Giuseppe and Crampton, Sean J. and Davies, Alun M. and Riccardi, Carlo R. and O'keeffe, Gerard W. (2012) The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling. Biology Open, 1 (10). pp. 1016-1023. ISSN: 2046-6390 Gutierrez, Humberto and Castillo, Atahualpa and Monzon, Jimena and Urrutia, Araxi O. (2011) Protein amino acid composition: a genomic signature of encephalization in mammals. PloS One, 6 (11). pp. e27261. ISSN: 1932-6203 Gutierrez, Humberto and Davies, Alun M. (2011) Regulation of neural process growth, elaboration and structural plasticity by NF-κB. Trends in Neurosciences, 34 (6). pp. 316-25. ISSN: 0166-2236 Moubarak, Rana S and Solé, Carme and Pascual, Marta and Gutierrez, Humberto and Llovera, Marta and Pérez-García, M José and Gozzelino, Raffaella and Segura, Miguel F. and Iglesias-Guimarais, Victoria and Reix, Stéphanie and Soler, Rosa M. and Davies, Alun M. and Soriano, Eduardo and Yuste, Victor J. and Comella, Joan X. (2010) The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 30 (17). pp. 6094-9105. Gavaldà, Núria and Gutierrez, Humberto and Davies, Alun M. (2009) Developmental switch in NF-kappaB signalling required for neurite growth. Development (Cambridge, England), 136 (20). pp. 3405-3412. ISSN: 0950-1991 Gavaldà, Núria and Gutierrez, Humberto and Davies, Alun M. (2009) Developmental regulation of sensory neurite growth by the tumor necrosis factor superfamily member LIGHT. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 29 (6). pp. 1599-1607. Gutierrez, Humberto and O'Keeffe, Gerard W and Gavaldà, Núria and Gallagher, Denis and Davies, Alun M (2008) Nuclear factor kappa B signaling either stimulates or inhibits neurite growth depending on the phosphorylation status of p65/RelA. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 28 (33). pp. 8246-8256. Vizard, Thomas N. and O'Keeffe, Gerard W. and Gutierrez, Humberto and Kos, Claudine H. and Riccardi, Daniela and Davies, Alun M. (2008) Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor. Nature Neuroscience, 11 (3). pp. 285-291. ISSN: 1097-6256 O'Keeffe, Gerard W. and Gutierrez, Humberto and Pandolfi, Pier Paolo and Riccardi, Carlo and Davies, Alun M. (2008) NGF-promoted axon growth and target innervation requires GITRL-GITR signaling.. Nature Neuroscience, 11 (2). pp. 135-42. ISSN: 1097-6256 Gallagher, Denis and Gutierrez, Humberto and Gavalda, Nuria and O'Keeffe, Gerard and Hay, Ron and Davies, Alun M. (2007) Nuclear factor-kappaB activation via tyrosine phosphorylation of inhibitor kappaB-alpha is crucial for ciliary neurotrophic factor-promoted neurite growth from developing neurons. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 27 (36). pp. 9664-9669. Gutierrez, Humberto and Davies, Alun M. (2007) A fast and accurate procedure for deriving the Sholl profile in quantitative studies of neuronal morphology. Journal of Neuroscience Methods, 163 (1). pp. 24-30. ISSN: 0165-0270 Gutierrez, Humberto and Hale, Valerie A. and Dolcet, Xavier and Davies, Alun (2005) NF-kappaB signalling regulates the growth of neural processes in the developing PNS and CNS.. Development (Cambridge, England), 132 (7). pp. 1713-26. ISSN: 0950-1991 Sole, Carme and Dolcet, Xavier and Segura, Miguel F. and Gutierrez, Humberto and Diaz-Meco, Maria-Teresa and Gozzelino, Raffaella and Sanchis, Daniel and Bayascas, Jose R. and Gallego, Carme and Moscat, Jorge and Davies, Alun M. and Comella, Joan X. (2004) The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling. The Journal of Cell Biology, 167 (3). pp. 479-92. ISSN: 0021-9525 Gutierrez, Humberto and Dolcet, Xavier and Tolcos, Mary and Davies, Alun (2004) HGF regulates the development of cortical pyramidal dendrites. Development (Cambridge, England), 131 (15). pp. 3717-3726. ISSN: 0950-1991 González, Claudia L. and Miranda, Maria Isabel and Gutierrez, Humberto and Ormsby, Christopher and Bermúdez-Rattoni, Federico (2000) Differential participation of the NBM in the acquisition and retrieval of conditioned taste aversion and Morris water maze. Behavioural Brain Research, 116 (1). pp. 89-98. ISSN: 0166-4328 Gutierrez, Humberto and Gutiérrez, Ranier and Ramírez-Trejo, Luis and Silva-Gandarias, Ricardo and Ormsby, Christopher E. and Miranda, Maria Isabel and Bermúdez-Rattoni, Federico (1999) Redundant basal forebrain modulation in taste aversion memory formation. The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 19 (17). pp. 7661-7669.