个人简介
After completing her PhD from the National Chemical Laboratory (NCL), Pune, India Pallavi joined the research group of Dr John E Moses at The University of Nottingham, UK in 2007. Her independent research career started (2012) at the University of Lincoln where she was appointed as a Lecturer in Organic Chemistry within The School of Life Sciences, and later moved to The School of Chemistry. Her current research interest includes Synthetic Organic Chemistry and Chemical Biology.
Department Responsibilities
Year 1 Tutor
Module Leader in UG and PG Degree Programme
Subject Specialism
Synthetic Organic Chemistry and Chemical Biology
Qualifications
PhD — National Chemical Laboratory, University of Pune, India, 2007
Awards
Royal Society Research Grant — Royal Society, 2014
Senior Research Fellowship, 2003-2006 — CSIR, India, 2003
Junior Research Fellowship, 2001-2003 — CSIR, India, 2001
Professional Affiliations
HEA — Fellow
研究领域
Cyanamides: Exploring New Approaches Towards Heterocyclic Scaffolds — Awarded £124,363 by EPSRC in 2015
The development of continuous flow & photochemical syntheses of complex antimalarial natural products — Awarded £15,000 by Royal Society in 2014
Syntheses of complex antimalarial natural products — Awarded £10,119 by University of Lincoln Research Investment Fund in 2013
Targeting Helicase-Primase: A Fragment Based Approach towards New Inhibitors of Herpes Simplex Virus — Awarded £60,000 by University of Lincoln, College of Science, Studentship in 2013
近期论文
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Bhat, Shreesha V. and Robinson, David and Moses, John E. and Sharma, Pallavi (2016) Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides. Organic Letters, 18 (5). pp. 1100-1103. ISSN: 1523-7060
Roe, S. and Gunaratnam, M. and Spiteri, C. and Sharma, Pallavi and Alharthy, R. D. and Neidle, S. and Moses, J. E. (2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Organic and Biomolecular Chemistry, 13. pp. 8500-8504. ISSN: 1477-0520
Cousins, Alex R. O. and Ritson, Dougal and Sharma, Pallavi and Stevens, Malcolm F. G. and Moses, John E. and Searle, Mark S. (2014) Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences. Chemical Communications, 50. pp. 15202-15205. ISSN: 1359-7345
Moore, Jonathan C. and Davies, E. Stephen and Walsh, Darren A. and Sharma, Pallavi and Moses, John E. (2014) Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels–Alder reaction. Chemical communications, 50 (83). pp. 12523-12525. ISSN: 1359-7345
Powell, Kimberley J. and Han, Li-Chen and Sharma, Pallavi and Moses, John E. (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Organic Letters, 16 (8). pp. 2158-2161. ISSN: 1523-7060
Borreguero, Ana M. and Sharma, Pallavi and Spiteri, Christian and Velencoso, María M. and Carmona, Manuel S. and Moses, John E. and Rodríguez, Juan F. (2013) A novel click-chemistry approach to flame retardant polyurethanes. Reactive and Functional Polymers, 73 (9). pp. 1207-1212. ISSN: 1381-5148
Powell, Kimberley J. and Sharma, Pallavi and Richens, Joanna L. and Daviss, Benjamin M. and Moses, John E. and O'Shea, Paul (2012) Interactions of marine-derived γ-pyrone natural products with phospholipid membranes. Physical Chemistry Chemical Physics, 14 (42). pp. 14489-14491. ISSN: 1463-9076
Sharma, Pallavi and Powell, Kimberley J. and Burnley, James and Moses, John E. and Awaad, Amani S. (2011) Total synthesis of polypropionate derived y-pyrone natural products. Synthesis, 18. pp. 2865-2892. ISSN: 0039-7881
Sharma, Pallavi and Ritson, Dougal J. and Burnley, James and Moses, John E. (2011) A synthetic approach to Kingianin A based upon biosynthetic speculation. Chemical Communications, 47 (38). pp. 10605-10607. ISSN: 1359-7345
Sharma, Pallavi and Moorhouse, Adam D. and Moses, John E. (2011) Microwave enhanced tandem azidation-amidation of anilines. Synlett, 2011 (16). pp. 2384-2386. ISSN: 0936-5214
Moorhouse, Adam D. and Spiteri, Christian and Sharma, Pallavi and Zloh, Mire and Moses, John E. (2011) Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5. Chemical Communications, 47 (1). pp. 230-232. ISSN: 1359-7345
Sharma, Pallavi and Moses, John E. (2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and click linker. Org. Lett., 12 (12). pp. 2860-2863. ISSN: 1523-7060
Spiteri, Christian and Mason, Christopher and Zhang, Fengzhi and Ritson, Dougal J. and Sharma, Pallavi and Keeling, Steve and Moses, John E. (2010) An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne. Organic and Biomolecular Chemistry Articles, 8 (11). pp. 2537-2542. ISSN: 1477-0520
Sharma, Pallavi and Moses, John E. (2010) Photochemical studies of the tridachiahydropyrones. Synlett, 2010 (4). pp. 525-528. ISSN: 0936-5214
Spiteri, Christian and Sharma, Pallavi and Zhang, Fengzhi and Macdonald, Simon J. F. and Keeling, Steve and Moses, John E. (2010) An improved synthesis of 1,2-benzisoxazoles: TBAF mediated 1,3-dipolar cycloaddition of nitrile oxides and benzyne. Chemical Communications, 46 (8). pp. 1272-1274. ISSN: 1359-7345
Sharma, Pallavi and Lygo, Barry and Williams, Lewis and Moses, John E. (2009) Biomimetic synthesis and structural reassignment of the tridachiahydropyrones. Journal of the American Chemical Society, 131 (16). pp. 5966-5972. ISSN: 0002-7863
Sharma, Pallavi and Griffiths, Nicholas and Moses, John E. (2008) Biomimetic synthesis and structural revision of tridachiahydropyrone. Organic Letters, 10 (18). pp. 4025-4027. ISSN: 1523-7060
Chavan, Subhash P. and Sharma, Pallavi and Sivappa, Rasapalli and Kalkote, Uttam R. (2007) A practical and facile approach towards indole alkaloids: (-)-mitralactonine. Synlett, 2007 (1). pp. 79-82. ISSN: 0936-5214
Chavan, Subhash P. and Sharma, Pallavi and Sivappa, R. and Kalkote, Uttam R. (2006) A ring closing metathesis approach to the indole alkaloid mitralactonine. Tetrahedron Letters, 47 (52). pp. 9301-9303. ISSN: 0040-4039
Chavan, Subhash P and Praveen, Cherukupally and Sharma, Pallavi and Kalkote, U. R. (2005) An efficient stereoselective synthesis of (2S,4S,5R)-(-)- and (2R,4R,5S)-(+)-bulgecinine. Tetrahedron Letters, 46 (3). pp. 439-441. ISSN: 0040-4039
Chavan, Subhash P. and Sharma, Pallavi and Sivappa, Rasapalli and Bhadbhade, Mohan B. and Gonnade, Rajesh G. and Kalkote, Uttam R. (2003) Enantioselective synthesis of L-CCG-I. Journal of the American Chemical Society, 68 (17). pp. 6871-6819. ISSN: 0002-7863
Chavan, Subhash P. and Sharma, Pallavi and Ramakrishna, G. and Thakkar, Mahesh (2003) Iodine as an efficient catalyst in ionic Diels–Alder reactions of α,β-unsaturated acetals. Tetrahedron Letters, 44 (14). pp. 3001-3003. ISSN: 0040-4039