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Synthetic “Plastic Antibodies” based on Molecular Imprinting Technology Sensors and assays Polymer and surface engineering

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Warwick, C., Guerreiro, A., Gomez-Caballero, A., Wood, E., Kitson, J., Robinson, J., Soares, A. Conductance based sensing and analysis of soluble phosphates in wastewater, Biosensors and Bioelectronics, 2014, 52, 173-179, DOI: 10.1016/j.bios.2013.08.048 Poma, A., Guerreiro, A., Caygill, S., Moczko, E., Piletsky, S, Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water, RSC Advances, 2014, 4 (8), 4203-4206, DOI: 10.1039/C3RA46838K Chianella, I. , Guerreiro, A., Moczko, E., Caygill, J.S., Piletska, E.V., De Vargas Sansalvador, I.M.P., Whitcombe, M.J., Piletsky, S.A, Direct replacement of antibodies with molecularly imprinted polymer nanoparticles in ELISA - Development of a novel assay for vancomycin, Analytical Chemistry, 2013, 85 (17), 8462-8468, DOI: 10.1021/ac402102j Poma, A., Guerreiro, A., Whitcombe, M.J., Piletska, E.V., Turner, A.P.F., Piletsky, S.A., Solid-Phase Synthesis of Molecularly Imprinted Polymer Nanoparticles with a Reusable Template - "Plastic Antibodies", Advanced Functional Materials, 2013, 23 (22), 2821-2827, DOI: 10.1002/adfm.201202397 Moczko, E., Guerreiro, A., Piletska, E., Piletsky, S. PEG-stabilized core-shell surface-imprinted nanoparticles, Langmuir, 2013, 29 (31), 9891-9896, DOI: 10.1021/la401891f Moczko, E., Poma, A., Guerreiro, A., Perez De Vargas Sansalvador, I., Caygill, S., Canfarotta, F., Whitcombe, M.J., Piletsky, S. Surface-modified multifunctional MIP nanoparticles, Nanoscale, 2013, 5 (9), 3733-3741, DOI: 10.1039/c3nr00354j Ivanova-Mitseva, P., Guerreiro, A., Piletska, E.V., Whitcombe, M.J., Zhou, Z., Mitsev, P.A., Davis, F., Piletsky, S.A. Cubic molecularly imprinted polymer nanoparticles with a fluorescent core, Angewandte Chemie International Edition, 2012, 51 (21), 5196-5199, DOI: 10.1002/anie.201107644 Gomez-Caballero, A., Guerreiro, A., Karim, K., Piletsky, S., Goicolea, M.A., Barrio, R.J. Chiral imprinted polymers as enantiospecific coatings of stir bar sorptive extraction devices, Biosensors and Bioelectronics, 2011, 28, 25-32, DOI: 10.1016/j.bios.2011.06.048 Kyprianou, D., Guerreiro, A.R., Nirschl, M., Chianella, I., Subrahmanyam, S., Turner, A.P.F., Piletsky, S. The application of polythiol molecules for protein immobilisation on sensor surfaces, Biosensors and Bioelectronics, 2010, 25 (5), 1049-1055, DOI: 10.1016/j.bios.2009.09.030 Guerreiro, A.R., Chianella, I., Piletska, E., Whitcombe, M.J., Piletsky, S.A. Selection of imprinted nanoparticles by affinity chromatography, Biosensors and Bioelectronics, 2009, 24 (8), 2740-2743, DOI: 10.1016/j.bios.2009.01.013

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