Cullis, Paul M - University of Leicester

研究领域

Design and Synthesis of Molecular Probes Drug Delivery and Targeting Development of Polyamides as Tools and Therapeutic Agents

近期论文

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Huang WC, Cullis PM, Raven EL, Roberts GC. Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis.Metallomics. (2011) 3(4):410 – 416. Heyes, D. J.; Quinn, A; Cullis, P. M.; Lee, M.; Munro, A. W.; Scrutton, N. S. Internal electron transfer in multi-site redox enzymes is accessed by laser excitation of thiouredopyrene-3,6,8-trisulfonate (TUPS). Chemical Communications (2009), (9), 1124-1126. Hothi, P.; Lee, M.; Cullis, P. M.; Leys, D.; Scrutton, N. S. Catalysis by the Isolated Tryptophan Tryptophylquinone-Containing Subunit of Aromatic Amine Dehydrogenase Is Distinct from Native Enzyme and Synthetic Model Compounds and Allows Further Probing of TTQ Mechanism. Biochemistry (2008), 47(1), 183-194. Cullis, P. M., Green, R. E., Merson-Davies, L., Travis, N., Probing the mechanism of transport and compartmentalisation of polyamines in mammalian cells Chemistry & Biology (1999), 6, 717–729. Su, W., Gray, S. J., Dondi, R., G, Highly efficient synthesis of DNA-binding hairpin polyamides via the use of a new triphosgene coupling strategy Organic Letters (2009), 11(17), 3910-3913