Mukamolova, Galina - University of Leicester - School of Biological Sciences

研究领域

Molecular mechanisms of bacterial dormancy and resuscitation. Role of serine-threonine kinase in growth, cell wall remodelling and dormancy. Antimicrobial tolerance. Biomarkers of non-replicating persistence.

近期论文

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Turapov O, O’Connor BD, Sarybaeva AA, Williams C, Patel H, Kadyrov AS, Sarybaev AS, Woltmann G, Barer MR, Mukamolova GV. 2016. Phenotypically adapted Mycobacterium tuberculosis populations from ?sputum are tolerant to first line drugs. Antimicrob Agents Chemother, 2016 Feb 16. pii: AAC.01380-15. [Epub ahead of print]. O’Connor BD, Woltmann G, Patel H; Turapov O, Haldar P, Mukamolova GV. 2015. Can Resuscitation-promoting factors be used to improve culture rates of extrapulmonary tuberculosis? Int J Tuberc Lung Dis. 19(12): 1556-7. Turapov O, Loraine J, Jenkins CH, Barthe P, McFeely D, Forti F, Ghisotti D, Hesek D, Lee M, Bottrill AR, Vollmer W, Mobashery S, Cohen-Gonsaud M, Mukamolova GV. 2015. The external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growth. Open Biology, 5(7): 150025. Turapov O, Glenn S, Kana B, Makarov V, Andrew PW, Mukamolova GV. 2014. The in vivo environment accelerates generation of Resuscitation-promoting factor–dependent mycobacteria. Am J Respir Crit Care Med. 190: 1455-7. Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young D, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV. 2014. Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria. J Biol Chem. 289: 25241-9. Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young D, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV. 2014. Antimicrobial treatment improves mycobacterial survival in non-permissive growth conditions. Antimicrob Agents Chemother 58: 2798-806. Kaprelyants AS, Mukamolova GV, Ruggiero A, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA. 2012. Resuscitation-promoting factors (Rpf): in search of inhibitors. Protein Pept Lett. 19: 1026-34. Mukamolova GV, Turapov O, Malkin J, Woltmann G, Barer MR. 2010 Resuscitation-promoting factors reveal an occult population of tubercle bacilli in sputum. Am J Respir Crit Care Med 181: 174-80. Barthe P, Mukamolova GV, Roumestand C, Cohen-Gonsaud M. 2010. The structure of the PknB extracellular PASTA domain from Mycobacterium tuberculosis suggests a ligand-dependent kinase activation. Structure 18: 606-15. Ryadnov MG, Mukamolova GV, Hawrani AS, Spencer J, Platt R. 2010. RE coil: an antimicrobial peptide regulator. Angew Chem Int Ed Engl. 48: 9676-9. Young M, Artsatbanov V, Beller HR, Chandra G, Chater KF, Dover LG, Goh EB, Kahan T, Kaprelyants AS, Kyrpides N, Lapidus A, Lowry SR, Lykidis A, Mahillon J, Markowitz V, Mavromatis K, Mukamolova GV, Oren A, Rokem JS, Smith MC, Young DI, Greenblatt CL. 2010. Genome sequence of the Fleming strain of Micrococcus luteus, a simple free-living actinobacterium. J Bacteriol. 192: 841-60