Rosato, Ezio - University of Leicester - School of Biological Sciences

个人简介

I was born and grew-up in Mestre (Italy), which is part of the Venetian “dry-land” (terraferma). I studied at the University of Padova for my first degree. After military service in Rome, I won a national competition and obtained a PhD scholarship in Genetics. Although my ‘Dottorato’ was awarded by the University of Ferrara, my laboratory work was carried out in the Department of Biology at the University of Padova and in the Department of Genetics at the University of Leicester. I moved to Leicester permanently in 1994

研究领域

We are interested in the genes that regulate the clock and we study them by characterising their function, by examining their evolution, and by analysing their expression. We are also engaged in understanding how clock neurons (neurons expressing clock genes) are organised and how circadian information flow through their network. More recently we have started analysing other complex behaviours such as learning and memory, courtship and sleep.

近期论文

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Seear PJ, Tarling GA, Burns G, Goodall-Copestake WP, Gaten E, ?zkaya ?, Ezio Rosato (2010). Differential gene expression during the moult cycle of Antarctic krill (Euphausia superba) BMC Genomics, 11:582. Seear P J, Tarling GA, Teschke M, Meyer B, Thorne MAS , Clark MS, Gaten E, Ezio Rosato (2009) Effects of simulated light regimes on gene expression in Antarctic krill (Euphausia superba Dana) Journal of Experimental Marine Biology and Ecology, 381: 57-64. Sandrelli F., Costa R., Kyriacou C.P., Rosato E. (2008) Comparative analysis of circadian clock genes in insects. Insect Molecular Biology. 17: 447-463 Codd V., Dolezel D., Stehlik J., Piccin A., Garner K., Seth R., Straatman K., Louis E., Costa R., Sauman I., Kyriacou C.P., Rosato E. (2007). Circadian rhythm gene regulation in the housefly, Musca domestica. Genetics, 177: 1539-1551. Tauber E, Zordan M, Sandrelli F, Pegoraro M, Daga A, Osterwalder N, Selmin A, Etournay R, Monger K, Rosato E, Costa R, Kyriacou CP. (2007). Natural selection favours a newly derived timeless allele in Drosophila melanogaster. Science, 316: 1895-1898. Sandrelli F, Tauber E, Pegoraro M, Mazzotta G, Cisotto P, Landskron J, Stanewsky R, Piccin A, Rosato E, Zordan M, and Kyriacou CP Costa R. (2007). Molecular basis for natural selection at the timeless locus in Drosophila melanogaster. Science. 316: 1898-1900. Rosato E, Kyriacou CP (2006) Analysis of locomotor activity rhythms in Drosophila. Nature Protocols, 1: 559-568 Collins BH, Dissel S, Gaten E, Rosato E, Kyriacou CP. (2005) Disruption of Cryptochrome partially restores circadian rhythmicity to the arrhythmic period mutant of Drosophila. Proc. Natl. Acad. Sci. USA, 102: 19021-19026 Dissel S, Codd V, Fedic R, Garner K, Costa R, Kyriacou CP, Rosato E (2004) A constitutively active Drosophila CRYPTOCHROME. Nature Neuroscience. 7: 834-840 Rosato E, Codd, V., Mazzotta, G, Piccin, A., Zordan, M., Costa, R. & Kyriacou, C.P. (2001) Light-dependent interaction between Drosophila CRY and the clock protein PER mediated by the carboxy terminus of CRY. Current Biology 11: 909-917.