Jobling, Mark A. - University of Leicester - School of Biological Sciences

个人简介

I was brought up and educated in Durham, and went to the University of Oxford to study Biochemistry in 1981. I then did a DPhil at the Genetics Laboratory there, where I developed an interest in human Y chromosomes. In 1992 I moved to the Department of Genetics in Leicester to study human Y chromosome diversity, under an MRC Training Fellowship, where I have remained until today, including a series of three Wellcome Trust Senior Fellowships.

近期论文

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Maisano Delser, P., Neumann, R., Ballereau, S., Hallast, P., Batini, C., Zadik, D. and JOBLING, M.A. (2017) Signatures of human European Paleolithic expansion shown by resequencing of non-recombining X-chromosome segments. Eur. J. Hum. Genet., in press. Hallast, P., Maisano Delser, P., Batini, C., Zadik, D., Rocchi, M., Schempp, W., Tyler-Smith, C. and JOBLING, M.A. (2016) Great-ape Y-chromosome and mitochondrial DNA phylogenies reflect sub-species structure and patterns of mating and dispersal. Genome Res., 26, 427-439. doi:10.1101/gr.198754.115. (PubMed). JOBLING, M.A., Rasteiro, R., and Wetton, J.H. (2016) In the blood: the myth and reality of genetic markers of identity. Ethnic Racial Stud., 39, 142-161. doi:10.1080/01419870.2016.1105990. Sun, M., JOBLING, M.A., Taliun, D., Pramstaller, P.P., Egeland, T. and Sheehan, N.A. (2016) On the use of dense SNP marker data for the identication of distant relative pairs. Theor. Popul. Biol. 107, 14-25. doi: 10.1016/j.tpb.2015.10.002. (PubMed) Batini, C., Hallast, P., Zadik, D., Maisano Delser, P., Benazzo, A., Ghirotto, S., Arroyo-Pardo, E., Cavalleri, G.L., de Knijff, P., Myhre Dupuy, B., Eriksen, H.A, King, T.E., López de Munain, A., López-Parra, A.M., Loutradis, A., Milasin, J., Novelletto, A., Pamjav, H., Sajantila, A., Tolun, A., Winney, B., and JOBLING, M.A. (2015) Large-scale recent expansion of European patrilineages shown by population resequencing. Nature Commun., 6, 7152. doi:10.1038/ncomms8152. (PubMed) Balaresque, P., Poulet, N., Cussat-Blanc, S., Gerard, P., Quintana-Murci, L., Heyer, E., and JOBLING, M.A. (2015) Y-chromosome descent clusters and male differential reproductive success: Young lineage expansions dominate Asian pastoral nomadic populations. Eur. J. Hum. Genet., 23, 1413-1422. doi: 10.1038/ejhg.2014.285. (PubMed) Hallast, P., Batini, C., Zadik, D., Maisano Delser, P., Wetton, J.H., Arroyo-Pardo, E., Cavalleri, G.L., de Knijff, P., Destro Bisol, G., Myhre Dupuy, B., Eriksen, H.A, Jorde, L.B., King, T.E., Larmuseau, M.H., López de Munain, A., López-Parra, A.M., Loutradis, A., Milasin, J., Novelletto, A., Pamjav, H., Sajantila, A., Schempp, W., Sears, M., Tolun, A., Tyler-Smith, Van Geystelen, A., Watkins, S., Winney, B., and JOBLING, M.A. (2015) The Y-chromosome tree bursts into leaf: 13,000 high-confidence SNPs covering the majority of known clades. Mol. Biol. Evol., 32, 661-673. doi: 10.1093/molbev/msu327 (PubMed). You can download the vcf for this dataset here. Balaresque, P., King, T.E., Parkin, E.J., Heyer, E., Carvalho-Silva, D., Kraaijenbrink, T., de Knijff, P., Tyler-Smith, C. and JOBLING, M.A. (2014) Gene conversion violates the stepwise mutation model for microsatellites in Y-chromosomal palindromic repeats. Hum. Mut., 35, 609-617. (PubMed) Hallast, P., Balaresque, P., Bowden, G.R., Ballereau, S. and JOBLING, M.A. (2013) Recombination dynamics of a human Y-chromosomal palindrome: rapid GC-biased gene conversion, multi-kilobase conversion tracts, and rare inversions. PLoS Genet., 9: e1003666. doi:10.1371/journal.pgen.1003666. (PubMed) Balaresque, P., Bowden, G.R., Adams, S.M., Leung, H.-Y., King, T.E., Rosser, Z.H., Goodwin, J., Moisan, J.-P., Richard, C., Millward, A., Demaine, A.G., Barbujani, G., Previderè, C., Wilson, I.J., Tyler-Smith, C. and JOBLING, M.A. (2010) A predominantly Neolithic origin for European paternal lineages. PLoS Biol., 8, e1000285. doi:10.1371/journal.pbio.1000285. (PubMed) (LRA) Rosser, Z.H., Balaresque, P. and JOBLING, M.A. (2009) Gene conversion between the X chromosome and the male-specific region of the Y chromosome at a translocation hotspot. Am. J. Hum. Genet., 85, 130-134. (PubMed) (LRA) King, T.E. and JOBLING, M.A. (2009) Founders, drift and infidelity: the relationship between Y chromosome diversity and patrilineal surnames. Mol. Biol. Evol., 26, 1093-1102. (PubMed) (LRA) Adams, S.M., Bosch, E., Balaresque, P.L., Ballereau, S.J., Lee, A.C., Arroyo, E., López-Parra, A.M., Aler, M., Gisbert-Grifo, M.S., Carracedo, A., Lavinha, J., Martínez-Jarreta, B., Quintana-Murci, L., Picornell, A., Ramon, M., Skorecki, K., Behar, D.M., Calafell, F. and JOBLING, M.A. (2008) The genetic legacy of religious diversity and intolerance: paternal lineages of Christians, Jews and Muslims in the Iberian Peninsula. Am. J. Hum. Genet., 83, 725-736. (PubMed) (LRA) Bowden, G.R., Balaresque, P., King, T.E., Hansen, Z., Lee, A.C., Pergl-Wilson, G., Hurley, E., Roberts, S.J., Waite, P., Jesch, J., Jones, A.L., Thomas, M.G., Harding, S.E. and JOBLING, M.A. (2008) Excavating past population structures by surname-based sampling: the genetic legacy of the Vikings in northwest England. Mol. Biol. Evol., 25, 301-309. (PubMed) (LRA) King, T.E., Parkin, E.J., Swinfield, G., Cruciani, F., Scozzari, R., Rosa, A., Lim, S.-K., Xue, Y., Tyler-Smith, C. and JOBLING, M.A. (2007) Africans in Yorkshire? - the deepest-rooting clade of the Y phylogeny within an English genealogy. Eur. J. Hum. Genet., 15, 288-293. (PubMed) (LRA)