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研究领域

My research interests lie within the field of osteoarthritis and the degeneration and turnover of cartilage and bone. My work commenced on a rare form of osteoarthritis; alkaptonuria, which is still studied in my lab. My work on this condition has lead me to also focus on arthritis and the turnover of joint tissues in response to disease(s) due to discoveries made whilst studying alkaptonuria. I also have research interest in anatomy and its delivery as part of modern medical and allied health curricula.

近期论文

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Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageingTaylor, A.M., Hsueh, M., Ranganath, L., Gallagher, J., Dillon, J., Huebner, J., Catterall, J., Byers Kraus, V. 01/2017 In: Rheumatology. 56, 1, p. 156-164. 9 p. Analysis of melanin-like pigment synthesized from homogentisic acid, with or without tyrosine, and its implications in AlkaptonuriaTaylor, A.M., Vercruysse, K. 10/12/2016 In: Journal of Inherited Metabolic Disease Reports. 7 p. Sir William Turner (1832–1916) – Lancastrian, anatomist and champion of the Victorian eraWessels, Q., Correia, J.C., Taylor, A. 11/2016 In: Journal of Medical Biography. 24, 4, p. 500-506. 7 p. The social life of the dead: the role of post-mortem examinations in medical student socialisationGoodwin, D.S., Machin, L.L., Taylor, A.M. 1/07/2016 In: Social Science and Medicine. 161, p. 100-108. 9 p. A role for interleukins in ochronosis in a chondrocyte in vitro model of alkaptonuriaMistry, J., Jackson, D., Bukhari, M., Taylor, A. 07/2016 In: Clinical Rheumatology. 35, 7, p. 1849-1856. 7 p. Tyrosinase, could it be a missing link in ochronosis in alkaptonuria?Taylor, A.M., Kammath, V., Bleakley, A. 1/06/2016 In: Medical Hypotheses. 91, p. 77-80. 4 p. Health, disease and society in nineteenth century LancasterDass, S., Wessels, Q.B., Taylor, A.M. 06/2016 In: Morecambe Bay Medical Journal. 7, 6, p. 160-165. 6 p. Health, disease and societyDass, S., Wessels, Q.B., Taylor, A.M. 30/04/2016 In: The medical pioneers of nineteenth century Lancaster. Neopubli GmbH p. 6-19. 14 p. Medicine and the evolving medical marketTaylor, A.M., Wessels, Q.B., Correia, J.C. 30/04/2016 In: The medical pioneers of nineteenth century Lancaster. Neopubli GmbH p. 20-35. 16 p. The asylums and pioneers of psychiatric careShaw, H., Wessels, Q.B., Taylor, A.M., Chin-Quee, E. 30/04/2016 In: The medical pioneers of nineteenth century Lancaster. Neopubli GmbH p. 99-121. 23 p. The educationalist and medical reformerWessels, Q.B., Correia, J.C., Taylor, A.M. 30/04/2016 In: The medical pioneers of nineteenth century Lancaster. Neopubli GmbH p. 122-136. 15 p. The sanitary reformers and public healthWessels, Q.B., Taylor, A.M., Denfhy, J. 30/04/2016 In: The medical pioneers of nineteenth century Lancaster. Neopubli GmbH p. 81-98. 18 p. Bacterial toxins in the urine of patients with rheumatoid arthritis: a cause of the condition or an opportunistic result of it?Grace, L., Bukhari, M., Lauder, R.M., Bishop, L.A., Taylor, A.M. 04/2016 Osteoarticular cells tolerate short-term exposure to nitisinone-implications in alkaptonuriaMistry, J.B., Jackson, D.J., Bukhari, M., Taylor, A. 02/2016 In: Clinical Rheumatology. 35, 2, p. 513-516. 4 p. Anecdotes to the life and times of Sir Richard Owen (1804-1892) in LancasterWessels, Q., Taylor, A.M. 28/10/2015 In: Journal of Medical Biography. Development of a technique to identify Staphylococcal Enterotoxin fragments in urine from patients with Rheumatoid ArthritisGrace, L.E., Bukhari, M.A.S., Lauder, R.M., Taylor, A.M. 20/04/2015 Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone.Preston, A.J., Keenan, C.M., Sutherland, H., Wilson, P.J., Wlodarski, B., Taylor, A., Williams, D.P., Ranganath, L.R., Gallagher, J.A., Jarvis, J.C. 01/2014 In: Annals of the Rheumatic Diseases. 73, 1, p. 284-289. 6 p. AlkaptonuriaMistry, J., Bukhari, M., Taylor, A. 18/12/2013 In: Rare Diseases. 1, 7 p. Metabolic and endocrine diseases, cartilage calcification and arthritisTaylor, A. 03/2013 In: Current Opinion in Rheumatology. 25, 2, p. 198-203. 6 p. Recent advances in understanding the pathogenesis of ochronosis: Najnowsze post?py w zrozumieniu patogenezy ochronozyGallagher, J., Taylor, A., Boyde, A., Jarvis, J., Ranganath, L. 7/09/2012 In: Reumatologia. 50, 4, p. 316–323. 8 p. Ochronosis in a murine model of alkaptonuria is synonymous to that in the human conditionTaylor, A., Preston, A.J., Paulk, N.K., Sutherland, H., Keenan, C.M., Wilson, P.J.M., Wlodarski, B., Grompe, M., Ranganath, L.R., Gallagher, J.A., Jarvis, J.C. 08/2012 In: Osteoarthritis and Cartilage. 20, 8, p. 880-886. 7 p. Identification of trabecular excrescences, novel microanatomical structures, present in bone in osteoarthropathiesTaylor, A., Boyde, A., Davidson, J.S., Jarvis, J.C., Ranganath, L.R., Gallagher, J.A. 21/04/2012 In: European Cells and Materials. 23, p. 300-309. 10 p. Primary human osteoblast culturesDillon, J.P., Waring-Green, V.J., Taylor, A., Wilson, P.J.M., Birch, M., Gartland, A., Gallagher, J.A. 31/12/2011 In: Bone research protocols . Springer p. 3-18. 16 p. Collagen atomic scale molecular disorder in ochronotic cartilage from an alkaptonuria patient, observed by solid state NMR.Chow, W.Y., Taylor, A., Reid, D.G., Gallagher, J.A., Duer, M.J. 12/2011 In: Journal of Inherited Metabolic Disease. 34, 6, p. 1137-1140. 4 p. The role of calcified cartilage and subchondral bone in the initiation and progression of ochronotic arthropathy in alkaptonuria.Taylor, A., Boyde, A., Wilson, P.J.M., Jarvis, J.C., Davidson, J.S., Hunt, J.A., Ranganath, L.R., Gallagher, J.A. 12/2011 In: Arthritis and Rheumatism. 63, 12, p. 3887-3896. 10 p.

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