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Evaluation of the transferability of skills learnt using simulation into real life practiceHorrocks, J.L., Curtis, F., Grant, K. 2014 Proteomic insights into parasite biologyGinger, M.L., McKean, P.G., Burchmore, R., Grant, K.M. 08/2012 In: Parasitology. 139, 9, p. 1101-1102. 2 p. High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent KinaseWalker, R.G., Thomson, G., Malone, K., Nowicki, M.W., Brown, E., Blake, D.G., Turner, N.J., Walkinshaw, M.D., Grant, K., Mottram, J.C. 5/04/2011 In: PLoS Neglected Tropical Diseases. 5, 4, 11 p. Recombinant Leishmania mexicana CRK3:CYCA has protein kinase activity in the absence of phosphorylation on the T-loop residue Thr178.Gomez, F.C., Ali, N.O.M., Brown, E., Walker, R.G., Grant, K.M., Mottram, J.C. 06/2010 In: Molecular and Biochemical Parasitology. 171, 2, p. 89-96. 8 p. 6-Br-5methylindirubin-3′oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like death: Exploitation of GSK-3 for treating leishmaniasisXingi, E., Smirlis, D., Myrianthopoulos, V., Prokopios, M., Grant, K., Meijer, L., Mikros, E., Skaltsounis, A., Soteriadou, K. 10/2009 In: International Journal for Parasitology. 39, 12, p. 1289-1303. 15 p. Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro.Arambage, S.C., Grant, K.M., Pardo, I., Ranford-Cartwright, L., Hurd, H. 15/07/2009 In: Parasites and Vectors. 2, 1, 16 p. Trypanosomatid protein kinases as potential drug targets.Wiese, M., Morris, A., Grant, K.M. 2009 In: Antiparasitic and antibacterial drug discovery : from molecular targets to drug candidates.. Weinheim : Wiley-VCH p. 227-247. 21 p. ISBN: 978-3-527-32327-2. Targeting the Cell Cycle in the Pursuit of Novel Chemotherapies against Parasitic Protozoa.Grant, K.M. 2008 In: Current Pharmaceutical Design. 14, 9, p. 917-924. 8 p. Apoptosis-like death as a feature of malaria infection in mosquitoes.Hurd, H., Grant, K.M., Arambage, S.C. 03/2006 In: Parasitology. 132, Supple, p. S33-S47. The selective biological activity of indirubin-based inhibitors : applications in parasitology.Wells, C., McNae, I., Walkinshaw, M., Westwood, N.J., Grant, K.M. 2006 In: Indirubin, the red shade of indigo. Roscoff, France : Life in Progress Editions p. 259-267. 9 p. ISBN: 2951802900. Inhibitors of Leishmania mexicana CRK3 Cyclin-Dependent Kinase: Chemical Library Screen and Antileishmanial Activity.Grant, K.M., Dunion, M.H., Yardley, V., Skaltsounis, A., Marko, D., Eisenbrand, G., Croft, S.L., Meijer, L., Mottram, J.C. 08/2004 In: Antimicrobial Agents and Chemotherapy. 48, 8, p. 3033-3042. 10 p. Intracellular targets of paullones : identification by affinity chromatography using immobilized inhibitor.Knockaert, M., Wieking, K., Schmitt, S., Leost, M., Grant, K.M., Mottram, J.C., Kunick, C., Meijer, L. 12/07/2002 In: Journal of Biological Chemistry. 277, 28, p. 25493-25501. 9 p. The CRK3 protein kinase is essential for cell cycle progression of Leishmania mexicana.Hassan, P., Fergusson, D., Grant, K.M., Mottram, J.C. 6/04/2001 In: Molecular and Biochemical Parasitology. 113, 2, p. 189-198. 10 p. Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.Knockaert, M., Gray, N., Damiens, E., Chang, Y., Grellier, P., Grant, K.M., Fergusson, D., Mottram, J.C., Soete, M., Dubremetz, J., Le Roch, K., Doerig, C., Schultz, P.G., Meijer, L. 1/06/2000 In: Chemistry and Biology. 7, 6, p. 411-422. 12 p.

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