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Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARαKarwad, M.A., Macpherson, T., Wang, B., Theophilidou, E., Sarmad, S., Barrett, D.A., Larvin, M., Wright, K.L., Lund, J.N., O'Sullivan, S.E. 02/2017 In: FASEB Journal. 31, 2, p. 469-481. 13 p.
Raman spectroscopy: an evolving technique for live cell studiesSmith, R., Wright, K.L., Ashton, L. 21/06/2016
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Wright, K.L. 21/01/2016 In: Autophagy. 12, 1, 222 p.
Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epitheliumKoay, L., Rigby, R., Wright, K. 15/07/2014 In: American Journal of Physiology-Gastrointestinal and Liver Physiology. 307, p. G140-G148. 9 p.
Physiological intestinal oxygen modulates the Caco-2 cell model and increases sensitivity to the phytocannabinoid cannabidiolMacPherson, T., Armstrong, J., Criddle, D., Wright, K. 2014 In: In Vitro Cellular and Developmental Biology - Animal. 50, 5, p. 417-426. 10 p.
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeabilityAlhamoruni, A., Wright, K., Larvin, M., O'Sullivan, S.E. 04/2012 In: British Journal of Pharmacology. 165, 8, p. 2598-610. 13 p.
Safety of medicine and the use of animals in researchArchibald, K., Baxter, A.D., BéruBé, K., Bunton, D., Clotworthy, M., Coleman, B., Foster, C.S., Hillier, C., McFarlane, M., Patel, A., Pierscionek, B., Root, J., Thomas, G., Tsaioun, K., Wilkinson, J.M., Wilmut, I., Wright, K.L. 29/10/2011 In: The Lancet. 378, 9802, 1 p.
Open letter to UK Prime Minister David Cameron and Health Secretary Andrew Lansley on safety of medicinesArchibald, K., Coleman, R., Foster, C., Wright, K. 4/06/2011 In: The Lancet. 377, 9781, p. 1915. 1 p.
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability.Alhamoruni, A., Lee, A.C., Wright, K.L., Larvin, M., O'Sullivan, S.E. 10/2010 In: Journal of Pharmacology and Experimental Therapeutics. 335, 1, p. 92-102. 11 p.
Long term cannabinoid receptor (CB1) blockade in obesity : implications for the development of colorectal cancer.Wright, K.L., Robertson, D.A.F., Moyer, M.P., Ward, S.G. 15/04/2008 In: International Journal of Cancer. 122, 8, p. 1920-1921. 2 p.
Cannabinoid CB2 receptors in the gastrointestinal tract : a regulatory system in states of inflammation.Wright, K.L., Duncan, M., Sharkey, K.A. 01/2008 In: British Journal of Pharmacology. 153, 2, p. 263-270. 8 p.
Temporal variation in CB2R levels following T lymphocyte activation : evidence that cannabinoids modulate CXCL12-induced chemotaxis.Coopman, K., Smith, L.D., Wright, K.L., Ward, S.G. 03/2007 In: International Immunopharmacology. 7, 3, p. 360-371. 12 p.
Peripheral cannabinoid receptor, CB2, regulates bone mass.Ofek, O., Karsak, M., Leclerc, N., Fogel, M., Frenkel, B., Wright, K., Tam, J., Attar-Namdar, M., Kram, V., Shohami, E., Mechoulam, R., Zimmer, A., Bab, I. 17/01/2006 In: Proceedings of the National Academy of Sciences. 103, 3, p. 696-701. 6 p.
The Chemokines CXCL9, CXCL10, and CXCL11 Differentially Stimulate Gαi-Independent Signaling and Actin Responses in Human Intestinal Myofibroblasts.Kouroumalis, A., Nibbs, R.J., Aptel, H., Wright, K.L., Kolios, G., Ward, S.G. 15/10/2005 In: Journal of Immunology. 175, 8, p. 5403-5411. 9 p.
Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPARγ agonists: evidence for disparate functional effects which are independent of NF-κB and PPARγPatel, K.M., Wright, K.L., Whittaker, P., Chakravarty, P., Watson, M.L., Ward, S.G. 09/2005 In: Cellular Signalling. 17, 9, p. 1098-1110. 13 p.
Differential Expression of Cannabinoid Receptors in the Human Colon : Cannabinoids Promote Epithelial Wound Healing.Wright, K., Rooney, N., Feeney, M., Tate, J., Robertson, D., Welham, M., Ward, S. 08/2005 In: Gastroenterology. 129, 2, p. 437-453. 17 p.
Differential regulation of prostaglandin E biosynthesis by interferon-γ in colonic epithelial cells.Wright, K.L., Weaver, S.A., Patel, K., Coopman, K., Feeney, M., Kolios, G., Robertson, D.A.F., Ward, S.G. 04/2004 In: British Journal of Pharmacology. 141, 7, p. 1091-1097. 7 p.
Optimal Chemotactic Responses of Leukemic T Cells to Stromal Cell-Derived Factor-1 Requires the Activation of Both Class IA and IB Phosphoinositide 3-Kinases.Curnock, A.P., Sotsios, Y., Wright, K.L., Ward, S.G. 15/04/2003 In: Journal of Immunology. 170, 8, p. 4021-4030. 10 p.
Evidence That SHIP-1 Contributes to Phosphatidylinositol 3,4,5-Trisphosphate Metabolism in T Lymphocytes and Can Regulate Novel Phosphoinositide 3-Kinase Effectors.Freeburn, R.W., Wright, K.L., Burgess, S.J., Astoul, E., Cantrell, D.A., Ward, S.G. 15/11/2002 In: Journal of Immunology. 169, 10, p. 5441-5450. 10 p.
Regulatory role of phosphatidylinositol 3-kinase on TNF-α-induced cyclooxygenase 2 expression in colonic epithelial cells.Weaver, S.A., Russo, M.P., Wright, K.L., Kolios, G., Jobin, C., Robertson, D.A.F., Ward, S.G. 04/2001 In: Gastroenterology. 120, 5, p. 1117-1127. 11 p.
Interactions between Phosphatidylinositol 3-Kinase and Nitric Oxide: Explaining the ParadoxWright, K.L., Ward, S.G. 09/2000 In: Molecular Cell Biology Research Communications. 4, 3, p. 137-143. 7 p.
Interleukin-13 inhibits nitric oxide production in human colonic mucosa.Kolios, G., Wright, K.L., Linehan, J.D., Robertson, D.A.F., Westick, J. 2000 In: Hepato-Gastroenterology. 47, p. 714-717. 4 p.
Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation : evidence for an IL-13-driven PI3-kinase-dependent survival mechanism.Wright, K., Kolios, G., Westwick, J., Ward, S.G. 11/06/1999 In: Journal of Biological Chemistry. 274, 24, p. 17193-17201. 9 p.
C-X-C and C-C chemokine expression and secretion by the human colonic epithelial cell line, HT-29 : differential effect of T lymphocyte-derived cytokines.Kolios, G., Wright, K.L., Jordan, N.J., Leithead, J.B., Robertson, D.A.F., Westwick, J. 02/1999 In: European Journal of Immunology. 29, 2, p. 530-536. 7 p.
Activation of phosphatidylinositol 3-kinase by interleukin-13 - An inhibitory signal for inducible nitric-oxide synthase expression in the epithelial, cell line HT-29.Wright, K., Ward, S.G., Kolios, G., Westwick, J. 9/05/1997 In: Journal of Biological Chemistry. 272, p. 12626-12633. 8 p.