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D-Ala2-GIP-glu-PAL is neuroprotective in a chronic Parkinson's disease mouse model and increases BNDF expression while reducing neuroinflammation and lipid peroxidationLi, Y., Liu, W., Li, L., Holscher, C. 15/02/2017 In: European Journal of Pharmacology. 797, p. 162-172. 11 p.
Lixisenatide attenuates the detrimental effects of amyloid β protein on spatial working memory and hippocampal neurons in ratsCai, H., Wang, Z., Holscher, C., Yuan, L., Zhang, J., Sun, P., Li, J., Yang, W., Wu, M., Qi, J. 1/02/2017 In: Behavioural Brain Research. 318, p. 28-35. 8 p.
A novel bioresorbable device as a controlled release system for protecting cells from oxidative stress from Alzheimer’s DiseaseSalles, G.N., Pereira, F.A.d.S., Pacheco-Soares, C., Marciano, F.R., Holscher, C., Webster, T.J., Lobo, A.O. 20/10/2016 In: Molecular Neurobiology. 12 p.
Incretin-based therapy for type 2 diabetes mellitus is promising for treating neurodegenerative diseasesLi, Y., Li, L., Holscher, C. 10/2016 In: Reviews in the Neurosciences. 27, 7, p. 689-711. 23 p.
Novel incretin analogues improve autophagy and protect from mitochondrial stress induced by rotenone in SH-SY5Y cellsJalewa, J., Sharma, M.K., Holscher, C. 10/2016 In: Journal of Neurochemistry. 139, 1, p. 55-67. 13 p.
Therapeutic potential of genipin in central neurodegenerative diseasesLi, Y., Li, L., Holscher, C. 10/2016 In: CNS Drugs. 30, 10, p. 889-897. 9 p.
Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide analogues as novel treatments for Alzheimer's and Parkinson's diseaseH?lscher, C. 09/2016 In: Cardiovascular Endocrinology . 5, 3, p. 93-98. 6 p.
A novel dual GLP-1 and GIP incretin receptor agonist is neuroprotective in a mouse model of Parkinson’s disease by reducing chronic inflammation in the brainLijun, C., Li, D., Feng, P., Li, L., Xue, G., Li, G., Holscher, C. 13/04/2016 In: NeuroReport. 27, 6, p. 384-391. 8 p.
Neuroprotective role of (Val8)GLP-1-Glu-PAL in an in vitro model of Parkinson’s diseaseLi, L., Liu, K., Holscher, C., Li, G., Liu, Y. 16/03/2016 In: Neural Regeneration Research. 11, 2, p. 326-331. 6 p.
A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson′s disease by increasing expression of BNDFJi, C., Xue, G., Lijun, C., Feng, P., Li, D., Li, L., Li, G., Holscher, C. 1/03/2016 In: Brain Research. 1634, p. 1-11. 11 p.
Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathologyOlmos-Alonso, A., Schetters, S.T.T., Sri, S., Askew, K., Mancuso, R., Vargas-Caballero, M., Holscher, C., Perry, V.H., Gomez-Nicola, D. 1/03/2016 In: Brain. 139, 3, p. 891-907. 17 p.
Alzheimer's disease–like pathology has transient effects on the brain and blood metabolomePan, X., Nasaruddin, M.B., Elliott, C.T., McGuinness, B., Passmore, A.P., Kehoe, P.G., Holscher, C., McClean, P.L., Graham, S.F., Green, B.D. 02/2016 In: Neurobiology of Aging. 38, p. 151-163. 13 p.
Neuroprotective effects of a GIP analogue in the MPTP Parkinson's disease mouse modelLi, Y., Liu, W., Li, L., Holscher, C. 02/2016 In: Neuropharmacology. 101, p. 255-263. 9 p.
Wide-ranging alterations in the brain fatty acid complement of subjects with late Alzheimer’s disease as detected by GC-MSNasaruddin, M.L., Holscher, C., Kehoe, P., Graham, S.F., Green, B. 30/01/2016 In: American Journal of Translational Research. 8, 1, p. 154-165. 12 p.
A novel dual-glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptor agonist is neuroprotective in transient focal cerebral ischemia in the ratHan, L., Holscher, C., Xue, G., Li, G., Li, D. 6/01/2016 In: NeuroReport. 27, 1, p. 23-32. 10 p.
Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's diseaseJi, C., Xue, G., Li, G., Li, D., Holscher, C. 01/2016 In: Reviews in the Neurosciences. 27, 1, p. 61-70. 10 p.
Neuroprotective effects of geniposide in the MPTP mouse model of Parkinson's diseaseChen, Y., Zhang, Y., Li, L., Holscher, C. 5/12/2015 In: European Journal of Pharmacology. 768, p. 21-27. 7 p.
Neuroprotective effects of (Val8)GLP-1-Glu-PAL in the MPTP Parkinson's disease mouse modelZhang, Y., Chen, Y., Li, L., Holscher, C. 15/10/2015 In: Behavioural Brain Research. 293, p. 107-113. 7 p.
Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 miceMcClean, P.L., Jalewa, J., Holscher, C. 15/10/2015 In: Behavioural Brain Research. 293, p. 96-106. 11 p.
Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's diseaseLiu, W., Jalewa, J., Sharma, M., Li, G., Li, L., Holscher, C. 10/09/2015 In: Neuroscience. 303, p. 42-50. 9 p.
Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's diseaseLiu, W., Li, Y., Jalewa, J., Saunders-Wood, T., Li, L., H?lscher, C. 21/08/2015 In: European Journal of Pharmacology. 765, p. 284-290. 7 p.
Neuroprotective effects of geniposide on Alzheimer's disease pathologyLiu, W., Li, G., Holscher, C., Li, L. 08/2015 In: Reviews in the Neurosciences. 26, 4, p. 371-383. 13 p.
Pharmacological inhibition of CSF1R blocks microglial proliferation and prevents the progression of Alzheimer's-like pathologyOlmos-Alonso, A., Schetters, S.T., Sri, S., Askew, K., Vargas-Caballero, M., Holscher, C., Perry, V.H., Gomez-Nicola, D. 08/2015
Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's diseaseGraham, S.F., Chevallier, O.P., Elliott, C.T., Holscher, C., Johnston, J., McGuinness, B., Kehoe, P.G., Passmore, A.P., Green, B.D. 24/03/2015 In: PLoS ONE. 10, 3, 16 p.
Restoration of cerebral and systemic microvascular architecture in APP/PS1 transgenic mice following treatment with Liraglutide?Kelly, P., McClean, P.L., Ackermann, M., Konerding, M.A., Holscher, C., Mitchell, C.A. 12/02/2015 In: Microcirculation. 22, 2, p. 133-145. 13 p.