Fullwood, Nigel - Lancaster University - The Division of Biomedical and Life Sciences

个人简介

BSc Joint Hons. Genetics and Cell Biology. University of Manchester. 1982 MPhil Physiology. CNAA. 1989 PhD Biophysics. Oxford Research Unit, Open University. 1992

近期论文

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Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptideGregori, M., Taylor, M.N., Salvati, E., Re, F., Mancini, S., Balducci, C., Forloni, G., Zambelli, V., Sesana, S., Michael, M., Michail, C., Kolosov, O.V., Tinker-Mill, C.L., Sherer, M., Harris, S., Fullwood, N.J., Masserini, M., Allsop, D. 02/2017 In: Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 2, p. 723-732. 10 p. Development of functional human oral mucosal epithelial stem/progenitor cell sheets using a feeder-free and serum-free culture system for ocular surface reconstructionNakamura, T., Yokoo, S., Bentley, A.J., Nagata, M., Fullwood, N.J., Inatomi, T., Sotozono, C., Yamagami, S., Kinoshita, S. 14/11/2016 In: Scientific Reports. 6, 11 p. Using Raman spectroscopy to characterize biological materialsButler, H.J., Ashton, L., Bird, B., Cinque, G., Curtis, K., Dorney, J., Esmonde-White, K., Fullwood, N.J., Gardner, B., Martin-Hirsch, P.L., Walsh, M.J., McAinsh, M.R., Stone, N., Martin, F.L. 04/2016 In: Nature Protocols. 11, 4, p. 664-687. 24 p. Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylationLi, J., Tian, M., Cui, L., Dwyer, J., Fullwood, N.J., Shen, H., Martin, F.L. 2/02/2016 In: Scientific Reports. 6, 11 p. Rho-associated kinase inhibitor eye drop (Ripasudil) transiently alters the morphology of corneal endothelial cellsOkumura, N., Okazaki, Y., Inoue, R., Nakano, S., Fullwood, N.J., Kinoshita, S., Koizumi, N. 30/11/2015 In: Investigative Ophthalmology and Visual Science. 56, 12, p. 7560-7567. 8 p. A preliminary electron microscopic investigation into the interaction between Aβ1-42 peptide and a novel nanoliposome- coupled retro-inverso peptide inhibitor, developed as a potential treatment for Alzheimer's diseaseSherer, M., Fullwood, N.J., Taylor, M., Allsop, D. 1/10/2015 In: Journal of Physics: Conference Series. 644, 1, 4 p. Distinguishing nuclei-specific benzo[a]pyrene-induced effects from whole-cell alterations in MCF-7 cells using Fourier-transform infrared spectroscopyObinaju, B., Fullwood, N., Martin, F. 1/09/2015 In: Toxicology. 335, p. 27-34. 8 p. Gold nanoparticles as a substrate in bio-analytical near-infrared surface-enhanced Raman spectroscopyButler, H.J., Fogarty, S.W., Kerns, J.G., Martin-Hirsch, P.L., Fullwood, N.J., Martin, F.L. 17/03/2015 In: The Analyst. 140, 9, p. 3090-3097. 8 p. Ocular surface reconstruction with a tissue-engineered nasal mucosal epithelial cell sheet for the treatment of severe ocular surface diseasesKobayashi, M., Nakamura, T., Yasuda, M., Hata, Y., Okura, S., Iwamoto, M., Nagata, M., Fullwood, N.J., Koizumi, N., Hisa, Y., Kinoshita, S. 01/2015 In: Stem Cells Translational Medicine. 4, 1, p. 99-109. 11 p. Characterisation of the stem cell population in human endometriumAfami, M.E., Martin, F.L., Fullwood, N.J., Martin-Hirsch, P.L. 11/2014 Development of stem cell therapies for the treatment of ocular surface stem cell diseaseChrysostomou, E., Fullwood, N.J., Martin, F.L. 11/2014 Mapping the 3-D location of the stem cells in the human prostateAntoniou, A., Fullwood, N.J., Martin, F.L. 11/2014 Surface-enhanced Raman spectroscopy of the endothelial cell membraneFogarty, S.W., Patel, I.I., Martin, F.L., Fullwood, N.J. 4/09/2014 In: PLoS ONE. 9, 9, 7 p. Human periodontal ligament cell sheets cultured on amniotic membrane substrateAdachi, K., Amemiya, T., Nakamura, T., Honjyo, K., Kumamoto, S., Yamamoto, T., Bentley, A., Fullwood, N., Kinoshita, S., Kanamura, N. 09/2014 In: Oral Diseases. 20, 6, p. 582-590. 9 p. Using Fourier transform IR spectroscopy to analyze biological materialsBaker, M.J., Trevisan, J., Bassan, P., Bhargava, R., Butler, H.J., Dorling, K.M., Fielden, P.R., Fogarty, S.W., Fullwood, N.J., Heys, K.A., Hughes, C., Lasch, P., Martin-Hirsch, P.L., Obinaju, B., Sockalingum, G.D., Sulé-Suso, J., Strong, R., Walsh, M.J., Wood, B.R., Gardner, P., Martin, F.L. 08/2014 In: Nature Protocols. 9, 8, p. 1771-1791. 21 p. Infrared microspectroscopy indentifies biomelcular changes associated with chronic oxidative stress in mammary epithelium and stroma of breast tissues from healthy young women: implications for latent stages of breast carcinogenesisPatel, I., Shearer, D.A., Fogarty, S., Fullwood, N.J., Quaroni, L., Martin, F.L., Weisz, J. 1/02/2014 In: Cancer Biology and Therapy . 15, 2, p. 225-235. 11 p. LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasisNakamura, T., Hamuro, J., Takaishi, M., Simmons, S., Maruyama, K., Zaffalon, A., Bentley, A.J., Kawasaki, S., Nagata-Takaoka, M., Fullwood, N.J., Itami, S., Sano, S., Ishii, M., Barrandon, Y., Kinoshita, S. 2/01/2014 In: Journal of Clinical Investigation. 124, 1, p. 385-397. 13 p. Dose-related alterations of carbon nanoparticles in Mammalian cells detected using biospectroscopy: potential for real-world effectsLi, J., Strong, R., Trevisan, J., Fogarty, S.W., Fullwood, N.J., Jones, K.C., Martin, F.L. 3/09/2013 In: Environmental Science and Technology. 47, 17, p. 10005-10011. 7 p. Sub-cellular spectrochemical imaging of isolated human corneal cells employing synchrotron radiation-based Fourier-transform infrared microspectroscopyFogarty, S.W., Patel, I.I., Trevisan, J., Nakamura, T., Hirschmugl, C.J., Fullwood, N.J., Martin, F.L. 7/01/2013 In: The Analyst. 138, 1, p. 240-248. 9 p. Classification of test agent-specific effects in the Syrian hamster embryo assay (pH 6.7) using infrared spectroscopy with computational analysisAhmadzai, A.A., Trevisan, J., Pang, W., Patel, I.I., Fullwood, N.J., Bruce, S.W., Pant, K., Carmichael, P.L., Scott, A.D., Martin, F.L. 05/2012 In: Mutagenesis. 27, 3, p. 375-382. 8 p. The Syrian hamster embryo (SHE) assay (pH 6.7): mechanisms of cell transformation and application of vibrational spectroscopy to objectively score endpoint alterationsAhmadzai, A.A., Trevisan, J., Fullwood, N.J., Carmichael, P.L., Scott, A.D., Martin, F.L. 05/2012 Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial HomeostasisMort, R.L., Bentley, A.J., Martin, F.L., Collinson, J.M., Douvaras, P., Hill, R.E., Morley, S.D., Fullwood, N.J., West, J.D. 29/12/2011 In: PLoS ONE. 6, 12, p. -. 11 p. Combining immunolabeling and surface-enhanced Raman spectroscopy on cell membranesHodges, M., Kerns , J., Bentley, A.J., Fogarty, S., Patel, I.I., Martin, F.L., Fullwood, N.J. 12/2011 In: ACS Nano. 5, 12, p. 9535-9541. 7 p. Imaging sclera with hard X-ray microscopyFullwood, N.J., Martin, F., Bentley, A., Lee, J.P., Lee, S.J. 07/2011 Corneal epithelialisation on surface-modified hydrogel implants Artificial corneaMa, A., Zhao, B., Bentley, A.J., Brahma, A., MacNeil, S., Martin, F.L., Rimmer, S., Fullwood, N.J. 03/2011 In: Journal of Materials Science: Materials in Medicine. 22, 3, p. 663-670. 8 p.