Benson, Fiona - Lancaster University - The Division of Biomedical and Life Sciences

个人简介

BSc (Hons) Biochemistry, Hull University, 1982 Ph.D. (Genetics) University of Nottingham, 1988 1987-1989 Postdoctoral research assistant, MRC Radiobiology Unit Harwell 1989-1992 Postdoctoral Research Fellow, Imperial Cancer Research Fund, South Mimms, Herts. 1992-1999 Chief Scientific Officer, Imperial Cancer Research Fund, South Mimms, Herts.

研究领域

My research interests focus on (i) Understanding the fundamental mechanisms associated with toxicity of aggregated proteins in neurodegenerative disorders such as Parkinson’s disease and Motor Neurone Disease.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degenerationFoulds, P., Davidson, Y., Mishra, M., Hobson, D.J., Humphreys, K.M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E.H., Benson, F.E., Allsop, D., Mann, D.M.A. 2009 In: Acta Neuropathologica. 118, 5, p. 647-658. 12 p. A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein.Tabner, B.J., Turnbull, S., King, J., Benson, F.E., El-Agnaf, O.M.A., Allsop, D. 07/2006 In: Free Radical Research. 40, 7, p. 731-739. 9 p. A strategy for designing inhibitors of α-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders.El-Agnaf, O.M.A., Paleologou, K.E., Greer, B., Abogrein, A.M., King, J., Salem, S.A., Fullwood, N.J., Benson, F.E., Hewitt, R., Ford, K.J., Martin, F., Harriott, P., Cookson, M.R., Allsop, D. 08/2004 In: FASEB Journal. 18, 11, p. 1315-1317. 3 p. Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D).Braybrooke, J.P., Li, J., Wu, L., Caple, F., Benson, F.E., Hickson, I.D. 28/11/2003 In: Journal of Biological Chemistry. 278, 48, p. 48357-48366. 10 p. XRCC3 and RAD51 modulate replication fork progression on damaged vertebrate chromosomes.Henry-Mowatt, J., Jackson, D., Masson, Y.J., Johnson, P.A., Clements, P.M., Benson, F.E., Thompson, L.H., Takeda, S., West, S.C., Caldecott, K.W. 04/2003 In: Molecular Cell. 11, 4, p. 1109-1117. 9 p. DNA damage responses : a combination of maintenance and fire-fighting.Benson, F.E., Carr, A.M. 08/2002 In: Microbiology Today. 29, 3, p. 123-124. 2 p. Identification and purification of two distinct complexes containing the five RAD51paralogs.Masson, J.Y., Tarsounas, M.C., Stasiak, A.Z., Stasiak, A., Shah, R., McIlwraith, M.J., Benson, F.E., West, S.C. 15/12/2001 In: Genes and Development. 15, 24, p. 3296-3307. 12 p. Complex formation by the human RAD51C and XRCC3 recombination repair proteins.Masson, J.Y., Stasiak, A.Z., Stasiak, A., Benson, F.E., West, S.C. 17/07/2001 In: Proceedings of the National Academy of Sciences. 98, 15, p. 8440-8446. 7 p. Identification and characterisation of a RAD51 gene from Leishmania major.McKean, P.G., Keen, J.G., Smith, D.F., Benson, F.E. 07/2001 In: Molecular and Biochemical Parasitology. 115, 2, p. 209-216. 8 p. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.Masson, J.Y., Davies, A.A., Hajibagheri, N., Van Dyck, E., Benson, F.E., Stasiak, A.Z., Stasiak, A., West, S.C. 11/1999 In: EMBO Journal. 18, 22, p. 6552-6560. 9 p. Mouse Rad 54 affects DNA conformation and DNA-damage-induced Rad51 foci formation.Tan, T.L.R., Essers, J., Citterio, E., Swagemakers, S.M.A., De Wit, J., Benson, F.E., Hoeijmakers, J.H.J., Kanaar, R. 26/03/1999 In: Current Biology. 9, 6, p. 325-328. 4 p.