Shearman, Gemma - Kingston University - School of Pharmacy and Chemistry

研究领域

1. Engineering principles in membrane biophysics 2. Designer lipids and mesoscale materials for future drug delivery 3. Tools and technologies for health-related applications Aligned with the above is a side interest in the democratisation of science. Pedagogic research interests include curriculum design and revision technique.

近期论文

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F.L. Lopez, G.C. Shearman, S. Gaisford, G.R. Williams, Amorphous formulations of indomethacin and griseofulvin prepared by electrospinning. Mol. Pharmaceutics, 2014, DOI: 10.1021/mp500391y. U.E. Illangakoon, H. Gill, G.C. Shearman, M. Parhizkar, S. Mahalingam, N.P. Chatterton, G.R. Williams, Fast dissolving paracetamol / caffeine nanofibers prepared by electrospinning. Int. J. Pharm, 2014, 477(1-2), 369-379. V.D. Gordon, P.A. Beales, G.C. Shearman, Z. Zhao, J.M. Seddon, W.C.K. Poon, S.U. Egelhaaf, Solid-like domains in mixed lipid bilayers: effect of membrane lamellarity and transition pathway. In Advances in Planar Lipid Bilayers and Liposomes, eds. A. Iglic, C.V. Kulkarni, ADPLAN, UK: Academic Press, 2014, 20, 137-154. G.C. Shearman, Taking 'Concepts in Chemistry' to completion: redesigning a first-year undergraduate module, Investigations in University Teaching and Learning, 2014, 9, 36-42. G.C. Shearman, N.J. Brooks, G.J.T. Tiddy, M. Sztucki, R.H. Templer, R.V. Law, O. Ces, J.M. Seddon, A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects. Soft Matter, 2011, 7(9), 4386-4390. A.I.I. Tyler, G.C. Shearman, N.J. Brooks, H. Delacroix, R.V. Law, R.H. Templer, O. Ces, J.M. Seddon, Hydrostatic pressure effects on a hydrated lipid inverse micellar Fd3m cubic phase. Phys. Chem. Chem. Phys., 2011, 13(8), 3033-3038. G.C. Shearman, A.I.I. Tyler, N.J. Brooks, R.H. Templer, O. Ces, R.V. Law, J.M. Seddon, Ordered micellar and inverse micellar lyotropic phases. Liq. Cryst., 2010, 37(6-7), 679-694. G.C. Shearman, O. Ces, R.H. Templer, Towards an understanding of phase transitions between inverse bicontinuous cubic lyotropic liquid crystalline phases. Soft Matter, 2010, 6, 256-262. G.C. Shearman, A.I.I. Tyler, N.J. Brooks, R.H. Templer, O. Ces, R.V. Law, J.M. Seddon, A 3-D hexagonal inverse micellar lyotropic phase. J. Am. Chem. Soc., 2009, 131(5), 1678-1679. G.C. Shearman, S. Ugazio, L. Soubiran, J. Hubbard, O. Ces, J.M. Seddon, R.H. Templer, Factors controlling the stability of a kinetically hindered lamellar-lamellar transition. J. Phys. Chem. B, 2009, 113(7), 1948-1953. G.C. Shearman, S. Ugazio, L. Soubiran, J. Hubbard, O. Ces, J.M. Seddon, R.H. Templer, The lyotropic phase behaviour of ester quaternary surfactants. J. Coll. Interface Sci., 2009, 331(2), 463-469. G.C. Shearman, G. Yahioglu, J. Kirstein, L.R. Milgrom, J.M. Seddon, Synthesis and phase behaviour of ?-octaalkyl porphyrins. J. Mat. Chem., 2009, 19(5), 598-604. D.P. Lydon, D. Albesa-Jove, G.C. Shearman, J.M. Seddon, J.A.K. Howard, T.B. Marder, P.J. Low, The synthesis and liquid crystalline behaviour of alkoxy-substituted derivatives of 1,4-bis(phenylethynyl)benzene. Liq. Cryst., 2009, 35(2), 119-132. D.R. Casey, S.C. Sebai, G.C. Shearman, O. Ces, R.V. Law, R.H. Templer, A.D. Gee, Formulation affects the rate of membrane degradation catalyzed by cationic amphiphilic drugs. Ind. Eng. Chem. Res., 2008, 47(3), 650-655. G.C. Shearman, B.J. Khoo, M.-L. Motherwell, K.A. Brakke, O. Ces, C.E. Conn, J.M. Seddon, R.H. Templer, Calculations of and evidence for chain packing stress in inverse lyotropic bicontinuous cubic phases. Langmuir, 2007, 23(13), 7276-7285. G.C. Shearman, G.S. Attard, A.N. Hunt, S. Jackowski, M. Baciu, S.C. Sebai, X. Mulet, J.A. Clarke, R.V. Law, C. Plisson, C.A. Parker, A. Gee, O. Ces, R.H. Templer, Using membrane stress to our advantage. Biochem. Soc. Trans., 2007, 35(3), 498-501. M. Baciu, S.C. Sebai, O. Ces, X. Mulet, J.A. Clarke, G.C. Shearman, R.V. Law, R.H. Templer, C. Plisson, C.A. Parker, A. Gee, Degradative transport of cationic amphiphilic drugs across phospholipid bilayers. Phil. Trans. R. Soc. A, 2006, 364(1847), 2597-2614. J.M. Seddon, A.M. Squires, C.E. Conn, O. Ces, A.J. Heron, X. Mulet, G.C. Shearman, R.H. Templer, Pressure-jump X-ray studies of liquid crystal transitions in lipids. Phil. Trans. R. Soc. A, 2006, 364(1847), 2635-2655. G.C. Shearman, O. Ces, R.H. Templer, J.M. Seddon, Inverse lyotropic phases of lipids and membrane curvature. J. Phys. Condens. Matter, 2006, 18(28), S1105-S1124. D.S. Valkovska, G.C. Shearman, C.D. Bain, R.C. Darton, J. Eastoe, Adsorption of ionic surfactants at an expanding air-water interface. Langmuir, 2004, 20(11), 4436-4445. T. Battal, G.C. Shearman, D. Valkovska, C.D. Bain, R.C. Darton, J. Eastoe, Determination of the dynamic surface excess of a homologous series of cationic surfactants by ellipsometry. Langmuir, 2003, 19(4), 1244-1248.