个人简介
2016 - present
1996 - 2000 DPhil in Medical Molecular Microbiology at the University of Oxford
1993 - 1996 BSc Hons in Biological Sciences, specialising in Molecular Biology, at the University of Exeter
近期论文
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The role of apolipoprotein N-acyl transferase (Lnt) in the lipidation of vaccine antigen, Factor H binding protein, of Neisseria meningitidis strain MC58 and its potential as a novel drug target. da Silva RAG, Churchward CP, Karlyshev AV, Eleftheriadou O, Snabaitis AK, Longman MR, Ryan A, Griffin R* British Journal of Pharmacology 2016 doi:10.1111/bph.13660
Insight into proteomic investigations of Neisseria meningitidis serogroup C strain L91543 from analysis of its genome sequence. Karlyshev AV, Snyder LA, McFadden J, Griffin R*. FEMS Microbiol Lett. 2015 362(9).
The Future of Tuberculosis Vaccinology. Thole, J, Griffin R, Young DB. (2010) Lung Biology in Health and Disease, vol 237. Tuberculosis Fourth Edition The Essentials edited by Raviglione MC @ Informa Healthcare USA Inc., New York.
Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Rosas-Magallanes V, Stadthagen-Gomez G, Rauzier J, Barreiro LB, Tailleux L, Boudou F, Griffin R, Nigou J, Jackson M, Gicquel B, Neyrolles O. Infect Immun. 2007 75(1):504-7.
Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives. Stadthagen G, Jackson M, Charles P, Boudou F, Barilone N, Huerre M, Constant P, Liav A, Bottova I, Nigou J, Brando T, Puzo G, Daffé M, Benjamin P, Coade S, Buxton RS, Tascon RE, Rae A, Robertson BD, Lowrie DB, Young DB, Gicquel B, Griffin R*. Microbes Infect. 2006 8(8):2245-53.
The Future of Tuberculosis Vaccinology. Griffin R*, Young DB. (2006) Lung Biology in Health and Disease, vol 219; Reichman and Hershfield's Tuberculosis. A Comprehensive, International Approach Third Edition edited by Raviglione MC @ Informa Healthcare USA Inc., New York.
p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis. Stadthagen G, Korduláková J, Griffin R, Constant P, Bottová I, Barilone N, Gicquel B, Daffé M, Jackson M. J Biol Chem. 2005 9;280(49):40699-706.
Digalactoside expression in the lipopolysaccharide of Haemophilus influenzae and its role in intravascular survival. Griffin R*, Bayliss CD, Herbert MA, Cox AD, Makepeace K, Richards JC, Hood DW, Moxon ER. Infect Immun. 2005 73(10):7022-6.
Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of Haemophilus influenzae and its role in bacterial resistance to complement-mediated killing. Griffin R*, Cox AD, Makepeace K, Richards JC, Moxon ER, Hood DW. Infect Immun. 2005 73(4):2213-21.
The role of lex2 in lipopolysaccharide biosynthesis in Haemophilus influenzae strains RM7004 and RM153. Griffin R, Cox AD, Makepeace K, Richards JC, Moxon ER, Hood DW. Microbiology. 2003 149 (Pt 11):3165-75.
Pathogenesis Due to Type b Haemophilus influenzae (2003). Aubrey, R* and Tang, C. Methods in Molecular Medicine, vol 71: Haemophilus influenzae Protocols edited by Herbert M @ Humana Press Inc., Totowa, N. J.(Published under maiden name)