Loweth , Anne - Keele University - School of Life Sciences

个人简介

I was appointed as a Lecturer at Keele University in 2003 and was promoted to Senior Lecturer in 2006. Having worked in the pharmaceutical industry for a number of years, I took a career break to have my family in 1985 before coming to Keele in 1989, as a mature undergraduate student. I obtained a BSc (Hons) in Biochemistry in 1992 and enjoyed the academic environment so much that I stayed on to complete my PhD, on the mechanisms of cell death in the endocrine pancreas, in 1995. I then spent a further three years at Keele as a postdoctoral research fellow, continuing my research in the field of diabetes mellitus, before taking up a lectureship at Liverpool John Moores University in 1998. Five years later I came back to Keele – there’s obviously something about the place that I like!

近期论文

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Watson D and Loweth AC. 2009. Oxidative and nitrosative stress in beta-cell apoptosis: their contribution to beta-cell loss in type 1 diabetes mellitus. Br J Biomed Sci, vol. 66(4), 208-215. link> doi> WATSON D, HOSKER BS, HAZLEWOOD SA, SCARPELLO JHB, LOWETH AC. 2008. A bioinformatics approach to assessing the functional and structural role of protein S-nitrosylation in beta cell apoptosis. Diabetic Medicine, vol. 25(Suppl 1), 49. Watson D, Kinsey E, Hoskert BS, Hazlewood SA, Scarpello JHB, Loweth AC. 2007. A role for mitochondrial calcium uptake in oxidant-induced beta-cell death. DIABETIC MEDICINE, vol. 24, 34. link> WATSON D, HAZELWOOD SA, SCARPELLO JHB, LOWETH AC. 2007. Differential use of calcium stores in reactive oxygen species-dependent pancreatic beta cell death. Diabetologia, vol. 50(Suppl 1), Article S182. Hosker BS, Bilton RF, Lowe GM, Loweth AC. 2003. Sequential nitrosylation, p38MAPK activation and apoptosis in RINm5F beta-cells in response to nitric oxide. DIABETOLOGIA (vol. 46, pp. A185-A186). link>