Aida, Takuzo - The University of Tokyo - Department of Chemistry and Biotechnology

个人简介

In 1996, he was appointed as a researcher of JST PRESTO Project "Fields and Reactions". In 2000, he then held an appointment as the leader of ERATO Project on "NANOSPACE", followed by ERATO–SORST Project in 2006. In 2008, he was also appointed as a director for RIKEN Institute. Since 2013, he has been serving as the deputy director for Riken Center for Emergent Matter Science (CEMS). Education BS. Faculty of Engineering, Yokohama National University (1979) MS. Graduate School of Engineering, The University of Tokyo (1981) Ph.D Graduate School of Engineering, The University of Tokyo (1984) Antecedents 1984–1989: Research Assistant, Faculty of Engineering, The University of Tokyo 1985: Visiting Scientist, IBM Almaden Research Center, San Jose, USA 1989–1991: Lecturer, Faculty of Engineering, The University of Tokyo 1991–1996: Associate Professor, Faculty of Engineering, The University of Tokyo 1996–2022: Professor, School of Engineering, The University of Tokyo 2021–Present: Exective Fellow, Kao Corporation 2022–Present: Distinguished Professor, School of Engineering, The University of Tokyo

研究领域

(1) controlled macromolecular synthesis with mesoporous inorganic materials, (2) photo and supramolecular chemistry of dendritic macromolecules, (3) mesoscopic materials sciences, and (4) bio-related molecular recognitions and catalyses.

近期论文

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Simulating Assembly Landscapes for Comprehensive Understanding of Supramolecular Polymer–Solvent Systems Stef A.H. Jansen, Elisabeth Weyandt, Tsubasa Aoki, Takayoshi Akiyama, Yoshimitsu Itoh, Ghislaine Vantomme, Takuzo Aida, and E.W. Meijer J. Am. Chem. Soc., 2023, in press. Blending to Make Nonhealable Polymers Healable: Nanophase Separation Observed by CP/MAS 13C NMR Analysis Yuta Fujisawa, Yiling Nan, Atsushi Asano, Yu Yanagisawa, Keiichi Yano, Yoshimitsu Itoh, Takuzo Aida Angew. Chem. Int. Ed. 2023, 62, e202214444. [DOI:10.1002/anie.202214444] Reconstitution of Microtubule into GTP-Responsive Nanocapsules Noriyuki Uchida, Ai Kohata, Kou Okuro, Annalisa Cardellini, Chiara Lionello, Eric A. Zizzi, Marco A. Deriu, Giovanni M. Pavan, Michio Tomishige, Takaaki Hikima, and Takuzo Aida Nature Commun. 2022, 13, 5424. [DOI:10.1038/s41467-022-33156-5] Ultrafast Water Permeation through Nanochannels with A Densely Fluorous Interior Surface Yoshimitsu Itoh, Shuo Chen, Ryota Hirahara, Takeshi Konda, Tsubasa Aoki, Takumi Ueda, Ichio Shimada, James J. Cannon, Cheng Shao, Junichiro Shiomi, Kazuhito V. Tabata, Hiroyuki Noji, Kohei Sato, and Takuzo Aida Science, 2022, 376, 738–743 (highlighted by Science and C&EN). [DOI:10.1126/science.abd0966] Supramolecular Polymerization of a Photo-Fluttering Chiral Monomer: A Temporarily Suspendable Chain Growth by Light Tsubasa Aoki, Michihisa Ueda, Takuzo Aida, Yoshimitsu Itoh J. Am. Chem. Soc., 2022, 144, 7080–7084. [DOI:10.1021/jacs.2c02176] Anomalous Chiral Transfer: Supramolecular Polymerization in a Chiral Medium of a Mesogenic Molecule Xu-Jie Zhang, Daiki Morishita, Tsubasa Aoki, Yoshimitsu Itoh, Keiichi Yano, Fumito Araoka, and Takuzo Aida Chem. Asian J., 2022, e202200223. [DOI:10.1002/asia.202200223] Expanding Quasiperiodicity in Soft Matter: Supramolecular Decagonal Quasicrystals by Binary Giant Molecule Blends Yuchu Liu, Tong Liu, Xiao-Yun Yan, Qing-Yun Guo, Huanyu Lei, Zongwu Huang, Rui Zhang, Jing Wang, Wang Yu, Feng Liu, Fenggang Bian, E.W. Meijer, Takuzo Aida, Mingjun Huang, and Stephen Z.D. Cheng Proc. Natl. Acad. Sci. USA, 2022, 19, e21153041119. [DOI:10.1073/pnas.2115304119] Tuning the Donor–Acceptor Interactions in Phase-Segregated Block Molecules Brigitte Lamers, Martin van Son, Freek V. de Graaf, Bart Bersselaar, Bas de Waal, Kazuki Komatsu, Hiroshi Sato, Takuzo Aida, Jose Berrocal, Anja Palmans, Ghislaine Vantomme, Stefan Meskers, and Egbert W. Meijer Material Horizons 2022, 9, 294–302. [DOI: 10.1039/d1mh01141c] Supramolecular Polymerization: Personal History and Outlook Kiyoshi Morishita, Takuzo Aida Asia Chem., 2021, 12, 20–25. [DOI:10.5167/acm00019] Propagating Wave in a Fluid by Coherent Motion of 2D Colloids Koki Sano, Xiang Wang, Zhifang Sun, Satoshi Aya, Fumito Araoka, Yasuo Ebina, Takayoshi Sasaki, Yasuhiro Ishida, and Takuzo Aida Nature Communications 2021, 12, 6771. [DOI: 10.1038/s41467-021-26917-1] Ultralong Organic Phosphorescent Foams with High Mechanical Strength Suzhi Cai, Zhifang Sun, He Wang, Xiaokang Yao, Huili Ma, Wenyong Jia, Shuxu Wang, Zhihao Li, Huifang Shi, Zhongfu An, Yasuhiro Ishida, Takuzo Aida,and Wei Huang J. Am. Chem. Soc. 2021, 143, 16256–16263. [DOI: 10.1021/jacs.1c07674] An Elastic Metal–Organic Crystal with a Densely Catenated Backbone Wenjing Meng, Shun Kondo, Takuji Ito, Kazuki Komatsu, Jenny Pirillo, Yuh Hijikata, Yuichi Ikuhara, Takuzo Aida, and Hiroshi Sato Nature 2021, 598, 298–303 (highlighted by C&EN). [DOI: 10.1038/s41586-021-03880-x] Solvent-Free Autocatalytic Supramolecular Polymerization Zhen Chen, Yukinaga Suzuki, Ayumi Imayoshi, Xiaofan Ji, Kotagiri Venkata Rao, Yuki Omata, Daigo Miyajima, Emiko Sato, Atsuko Nihonyanagi, and Takuzo Aida Nature Materials 2022, 22, 253–261. [DOI: 10.1038/s41563-021-01122-z] Accumulated Lattice Strain as an Internal Trigger for Spontaneous Pathway Selection Hubiao Huang, Hiroshi Sato, Jenny Pirillo, Yuh Hijikata, Yong Sheng Zhao, Stephen Z. D. Cheng, and Takuzo Aida J. Am. Chem. Soc. 2021, 143, 15319–15325 (highlighted by JACS Spotlights). [DOI: 10.1021/jacs.1c06854] Mechanically Robust, Self-Healable Polymers Usable under High Humidity: Humidity-Tolerant Noncovalent Cross-Linking Strategy Yuta Fujisawa, Atsushi Asano, Yoshimitsu Itoh, and Takuzo Aida J. Am. Chem. Soc. 2021, 143, 15279–15285 (selected as “Cover Picture”). [DOI: 10.1021/jacs.1c06494] Photoreactive Molecular Glue for Enhancing the Efficacy of DNA Aptamers by Temporary-to-Permanent Conjugation with Target Proteins Ai Kohata, Ryosuke Ueki, Kou Okuro, P. K. Hashim, Shinsuke Sando, and Takuzo Aida J. Am. Chem. Soc. 2021, 143, 13937–13943 (highlighted by JACS Spotlights). [DOI: 10.1021/jacs.1c06816] Alternating Heterochiral Supramolecular Copolymerization Michihisa Ueda, Tsubasa Aoki, Takayoshi Akiyama, Takayuki Nakamuro, Keitaro Yamashita, Haruaki Yanagisawa, Osamu Nureki, Masahide Kikkawa, Eiichi Nakamura, Takuzo Aida, and Yoshimitsu Itoh J. Am. Chem. Soc. 2021, 143, 5121–5126. [DOI: 10.1021/jacs.1c00823] Bio-Adhesive Nanoporous Module : Toward Autonomous Gating Hyuna Jo, Takashi Kitao, Ayumi Kimura, Yoshimitsu Itoh, Takuzo Aida, and Kou Okuro Angew. Chem. Int. Ed. 2021, 60, 8932–8937 (selected as “Cover Picture”). [DOI: 10.1002/anie.202017117] A Structural Parameter to Link Molecular Geometry to Macroscopic Orientation in Discotic Liquid Crystals: Study of Metalloporphyrin Tapes Yoshiyuki Kobayashi, Atsuya Muranaka, Kenichi Kato, Akinori Saeki, Takayuki Tanaka, Masanobu Uchiyama, Atsuhiro Osuka, Takuzo Aida, and Tsuneaki Sakurai Chem. Commun. 2021, 57, 1206. [DOI: 10.1039/D0CC07241A] Mesoatom Alloys via Self-Sorting Approach of Giant Molecules Blends Yuchu Liu, Tong Liu, Xiao-Yun Yan, Qing-Yun Guo, Jian Wang, Rongchun Zhang, Shuailin Zhang, Zebin Su, Jiahao Huang, Geng-Xin Liu, Wei Zhang, Wei Zhang, Takuzo Aida, Kan Yue, Mingjun Huang, and Stephen Z.D. Cheng Giant 2020, 4, 100031. [DOI: 10.1016/j.giant.2020.100031] Boron Carbon Nitride Thin Films: From Disordered to Ordered Conjugated Ternary Materials Paolo Giusto, Hiroki Arazoe, Daniel Cruz, Paola Lova, Tobias Heil, Takuzo Aida, and Markus Antonietti J. Am. Chem. Soc. 2020, 142, 20883–20891 (highlighted by Science). [DOI: 10.1021/jacs.0c10945] A Mechanically Adaptive Hydrogel with a Reconfigurable Network Consisting Entirely of Inorganic Nanosheets and Water Koki Sano, Naoki Igarashi, Yasuo Ebina, Takayoshi Sasaki, Takaaki Hikima, Takuzo Aida, and Yasuhiro Ishida Nature Commun. 2020, 11, 6026. [DOI: 10.1038/s41467-020-19905-4] Anomalously Slow Conformational Change Dynamics of Polar Groups Anchored to Hydrophobic Surfaces in Aqueous Media Tengfei Fu, Hao Xing, Eric S. Silver, Yoshimitsu Itoh, Shuo Chen, Takuya Masuda, Kohei Uosaki, Feihe Huang, and Takuzo Aida Chem. Asian J. 2020, 15, 3321–3325. [DOI: 10.1002/asia.202000742] Photochemically Crushable and Regenerative Metal–Organic Framework Hiroshi Sato, Toshiya Matsui, Zhiyi Chen, Jenny Pirillo, Yuh Hijikata, and Takuzo Aida J. Am. Chem. Soc. 2020, 142, 14069–14073. [DOI: 10.1021/jacs.0c06615] Molecularly Engineered “Janus GroEL”: Application to Supramolecular Copolymerization with a Higher Level of Sequence Control Daiki Kashiwagi, Hao K. Shen, Seunghyun Sim, Koki Sano, Yasuhiro Ishida, Ayumi Kimura, Tatsuya Niwa, Hideki Taguchi, and Takuzo Aida J. Am. Chem. Soc. 2020, 142, 13310–13315. [DOI: 10.1021/jacs.0c05937] Supramolecular Polymerization: A Conceptual Expansion for Innovative Materials P. K. Hashim, Julian Bergueiro, Egbert W. Meijer, and Takuzo Aida Prog. Polym. Sci. 2020, 101250. [DOI: 10.1016/j.progpolymsci.2020.101250] Intracellular Photoactivation of Caspase-3 by Molecular Glues for Spatiotemporal Apoptosis Induction Nina B. Hentzen, Rina Mogaki, Saya Otake, Kou Okuro, and Takuzo Aida J. Am. Chem. Soc. 2020, 142, 8080–8084 (selected as “Cover Picture”). [DOI: 10.1021/jacs.0c01823] Supramolecular Polymers — we've Come Full Circle Takuzo Aida and Egbert W. Meijer Isr. J. Chem. (Rosarium Philosophorum Macromolecules), 2020, 60, 1–16. [DOI: 10.1002/ijch.201900165] Distinct Pathways in “Thermally Bisignate Supramolecular Polymerization”:Spectroscopic and Computational Studies K. Venkata Rao, Mathijs Mabesoone, Daigo Miyajima, Atsuko Nihonyanagi, Egbert W. Meijer, and Takuzo Aida J. Am. Chem. Soc. 2020, 142, 598–605. [DOI: 10.1021/jacs.9b12044] Shine Bright Like a Diamond: New Light on an Old Polymeric Semiconductor Paolo Giusto, Daniel Cruz, Tobias Heil, Paola Lova, Hiroki Arazoe, Takuzo Aida, Davide Comoretto, Maddalena Patrini, and Markus Antonietti Adv. Mater. 2020, 32, 1908140. [DOI: 10.1002/adma.201908140] On Supramolecular Polymerization: Interview with Takuzo Aida Takuzo Aida Adv. Mater. 2019, 1905445. [DOI: 10.1002/adma.201905445] Tunable Electronic Properties by Ligand Coverage Control in PbS Nanocrystal Assemblies Liming Liu, Satria Zulkarnaen Bisri, Yasuhiro Ishida, Takuzo Aida and Yoshihiro Iwasa Nanoscale 2019, 11, 20467–20474. [DOI: 10.1039/C9NR07101F] One-Step Synthesis of an Adaptive Nanographene MOF: Adsorbed Gas-Dependent Geometrical Diversity Shun Suginome, Hiroshi Sato, Akihiro Hori, Akio Mishima, Yuki Harada, Shinpei Kusaka, Ryotaro Matsuda, Jenny Pirillo, Yuh Hijikata, and Takuzo Aida J. Am. Chem. Soc. 2019, 141, 15649–15655. [DOI: 10.1021/jacs.9b07732] Identification of a Frank–Kasper Z Phase from Shape Amphiphile Self-Assembly Zebin Su, Chih-Hao Hsu, Zihao Gong, Xueyan Feng, Jiahao Huang, Ruimeng Zhang, Yu Wang, Jialin Mao, Chrys Wesdemiotis, Tao Li, Soenke Seifert, Wei Zhang, Takuzo Aida, Mingjun Huang, and Stephen Cheng Nature Chem. 2019, 11, 899–905. [DOI: 10.1038/s41557-019-0330-x] Asymmetric Catalysis Mediated by a Mirror Symmetry-Broken Helical Nanoribbon Zhaocun Shen, Yutao Sang, Tianyu Wang, Jian Jiang, Yan Meng, Yuqian Jiang, Kou Okuro, Takuzo Aida, and Minghua Liu Nat. Commun. 2019, 10, 3976. [DOI: 10.1038/s41467-019-11840-3] Supramolecular Polymerization in Liquid Crystalline Media: Toward Modular Synthesis of Multifunctional Core-Shell Columnar Liquid Crystals Keiichi Yano, Takahiro Hanebuchi, Xu-Jie Zhang, Yoshimitsu Itoh, Yoshiaki Uchida, Takuro Sato, Keisuke Matsuura, Fumitaka Kagawa, Fumito Araoka, and Takuzo Aida J. Am. Chem. Soc. 2019, 141, 10033–10038 (selected as “Cover Picture”). [DOI: 10.1021/jacs.9b03961] Molecular Glue that Spatiotemporally Turns on Protein-Protein Interactions Rina Mogaki, Kou Okuro, Ryosuke Ueki, Shinsuke Sando, and Takuzo Aida J. Am. Chem. Soc. 2019, 141, 8035–8040 (highlighted by JACS Spotlights and Cover). [DOI: 10.1021/jacs.9b02427] An Electrochemical Cholesteric Liquid Crystalline Device for Quick and Low-Voltage Color Modulation Shoichi Tokunaga, Mengyan Zeng, Yoshimitsu Itoh, Fumito Araoka, and Takuzo Aida J. Vis. Exp. 2019, 144, e59244. [DOI: 10.3791/59244] Transferrin-Appended Nanocaplet for Transcellular siRNA Delivery into Deep Tissues Ai Kohata, P. K. Hashim, Kou Okuro, and Takuzo Aida J. Am. Chem. Soc. 2019, 141, 2862–2866 (highlighted by JACS Spotlights and Cover). [DOI: 10.1021/jacs.8b12501] Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags Rina Mogaki, Kou Okuro, Akio Arisaka, and Takuzo Aida J. Vis. Exp. 2019, 143, e58631. [DOI: 10.3791/58631] Stepwise Expansion of Layered Metal–Organic Frameworks for Nonstochastic Exfoliation into Porous Nanosheets Vonika Ka-Man Au, Kazuki Nakayashiki, Hubiao Huang, Shun Suginome, Hiroshi Sato, and Takuzo Aida J. Am. Chem. Soc. 2019, 141, 53–57. [DOI: 10.1021/jacs.8b09987] Nematic-to-Columnar Mesophase Transition by In situ Supramolecular Polymerization Keiichi Yano, Yoshimitsu Itoh, Fumito Araoka, Go Watanabe, Takaaki Hikima, and Takuzo Aida Science 2019, 363, 161–165. [DOI: 10.1126/science.aan1019] Columnar Liquid Crystalline Assembly of a U-Shaped Molecular Scaffold Stabilized by Covalent or Noncovalent Incorporation of Aromatic Molecules Yoshiki Shibuya, Yoshimitsu Itoh, and Takuzo Aida J. Polym. Sci. A, Polym. Chem. 2019, 57, 342–351. [DOI: 10.1002/pola.29186]