Zhang, Shuai - Pacific Northwest National Laboratory -

个人简介

Shuai Zhang is currently a research scientist at Pacific Northwest National Laboratory (PNNL). He is also affiliate faculty in the Department of Materials Science and Engineering at the University of Washington. His research delves into the design of biomolecular materials through assembly mechanisms, with a particular focus on elucidating the principles governing assembly dynamics, structures, and hierarchies, employing cutting-edge in situ/operando scanning probe microscopies. Additionally, he spearheads investigations in mineralization and surface sciences, with applications in clean energy technologies. He received his PhD, with a PhD prize awarded by the Danish Academy of Natural Sciences, from Aarhus University in Denmark. His doctoral research focused on understanding amyloid assembly with atomic force microscopy-based nanomechanical mapping. Throughout his career, Zhang has gained extensive experience in materials science, biophysics, and nanotechnology, developing a highly interdisciplinary approach to achieving rational design and assembly of biomimetic materials. Zhang has published more than 70 papers. Education PhD in nanoscience, Aarhus University, Denmark BS in materials chemistry, Jilin University, China

研究领域

Scanning probe micriscopy Atomic force microscopy Biomolecular materials Self-assembly 2D VdW materials Surface science Crystalization Automated synthesis Biocatalysis

近期论文

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Yadav Schmid S., X. Ma, J.A. Hammons, S.T. Mergelsberg, B.S. Harris, T.J. Ferron, and W. Yang, et al. 2024. "Influence of Peptoid Sequence on the Mechanisms and Kinetics of 2D Assembly." ACS Nano. PNNL-SA-192033. doi:10.1021/acsnano.3c10810 Yadav S.B., K. Lachowski, H.T. Chiang, L.D. Pozzo, J.J. De Yoreo, and S. Zhang. 2023. "Mechanisms of biomolecular self-assembly investigated through in situ observations of structures and dynamics." Angewandte Chemie International Edition 62, no. 48:Art. No. e202309725. PNNL-SA-181358. doi:10.1002/ange.202309725 Zhao M., S. Zhang, R. Zheng, S. Alamdari, C.J. Mundy, J. Pfaendtner, and L.D. Pozzo, et al. 2023. "Computational and Experimental Determination of the Properties, Structure, and Stability of Peptoid Nanosheets and Nanotubes." Biomacromolecules. PNNL-SA-183646. doi:10.1021/acs.biomac.3c00107 Davila Hernandez F.A., B. Jin, H. Pyles, S. Zhang, Z. Wang, T. Huddy, and A.K. Bera, et al. 2023. "Directing polymorph specific calcium carbonate formation with de novo protein templates." Nature Communications 14. PNNL-SA-186141. doi:10.1038/s41467-023-43608-1 Akkineni S., G. Doerk, C. Shi, B. Jin, S. Zhang, S. Habelitz, and J.J. De Yoreo. 2023. "Biomimetic mineral synthesis by nanopatterned supramolecular-block copolymer templates." Nano Letters 23, no. 10:4290-4297. PNNL-SA-184702. doi:10.1021/acs.nanolett.3c00480 Alberstein R.G., J.L. Prelesnik, E. Nakouzi, S. Zhang, J.J. De Yoreo, W.J. Pfaendtner, and F.A. Tezcan, et al. 2023. "Discrete orientations of interfacial waters direct crystallization of mica-binding proteins." The Journal of Physical Chemistry Letters 14, no. 1:80-87. PNNL-SA-178070. doi:10.1021/acs.jpclett.2c02948 Lachowski K., H.T. Chiang, W. Zhou, K. Torkelson, S. Zhang, J. Pfaendtner, and L.D. Pozzo. 2023. "Anisotropic Gold Nanomaterial Synthesis Using Peptide Facet Specificity and Timed Intervention." Langmuir. PNNL-SA-186539. doi:10.1021/acs.langmuir.3c01577 Balistreri G., I.R. Campbell, X. Li, J. Amorim, S. Zhang, E. Nance, and E. Roumeli. 2023. "Bacterial cellulose nanoparticles as a sustainable drug delivery platform for protein-based therapeuticsery platform for protein-based therapeutics." RSC Applied Polymers. PNNL-SA-191106. doi:10.1039/D3LP00184A Felsted R.G., A. Pant, A. Bard, X. Xia, D. Luntz-Martin, S. Dadras, and S. Zhang, et al. 2022. "Chemically Tunable Aspect Ratio Control and Laser Refrigeration of Hexagonal Sodium Yttrium Fluoride Upconverting Materials." Crystal Growth & Design 22, no. 6:3605-3612. PNNL-SA-172021. doi:10.1021/acs.cgd.1c01174 Zhang S., R. Sadre, B.A. Legg, H. Pyles, T. Perciano, E.W. Bethel, and D. Baker, et al. 2022. "Rotational Dynamics and Transition Mechanisms of Surface-Adsorbed Proteins." Proceedings of the National Academy of Sciences of the United States of America 119, no. 16:Art. No. e2020242119. PNNL-SA-171180. doi:10.1073/pnas.2020242119 Monahan M.C., M. Homer, S. Zhang, R. Zheng, C. Chen, J.J. De Yoreo, and B.M. Cossairt. 2022. "Impact of nanoparticle size and surface chemistry on peptoid self-assembly." ACS Nano 16, no. 5:8095–8106. PNNL-SA-172561. doi:10.1021/acsnano.2c01203 Kalinin S.V., S. Zhang, M. Valleti, H. Pyles, D. Baker, J.J. De Yoreo, and M. Ziatdinov. 2021. "Disentangling Rotational Dynamics and Ordering Transitions in a System of Self-Organizing Protein Nanorods via Rotationally Invariant Latent Representations." ACS Nano 15, no. 4:6471-6480. PNNL-SA-161461. doi:10.1021/acsnano.0c08914 Ma J., B. Cai, S. Zhang, T. Jian, J.J. De Yoreo, C. Chen, and F. Baneyx. 2021. "Nanoparticle-Mediated Assembly of Peptoid Nanosheets Functionalized with Solid-Binding Proteins: Designing Heterostructures for Hierarchy." Nano Letters 21, no. 4:1636-1642. PNNL-SA-159754. doi:10.1021/acs.nanolett.0c04285 Monahan M.C., B. Cai, T. Jian, S. Zhang, G. Zhu, C. Chen, and J.J. De Yoreo, et al. 2021. "Peptoid-Directed Assembly of CdSe Nanoparticles." Nanoscale 13, no. 2:1273-1282. PNNL-SA-158881. doi:10.1039/D0NR07509D Wang M., Y. Song, S. Zhang, X. Zhang, X. Cai, Y. Lin, and J.J. De Yoreo, et al. 2021. "Programmable two-dimensional nanocrystals assembled from POSS-containing peptoids as efficient artificial light-harvesting systems." Science Advances 7, no. 20:eabg1448. PNNL-SA-154183. doi:10.1126/sciadv.abg1448 Zhang S., J. Chen, J. Liu, H. Pyles, D. Baker, C. Chen, and J.J. De Yoreo. 2021. "Engineering Biomolecular Self-Assembly at Solid-Liquid Interfaces." Advanced Materials 33, no. 23:Article No. 1905784. PNNL-SA-153256. doi:10.1002/adma.201905784 Ziatdinov M., S. Zhang, O. Dollar, J. Pfaendtner, C.J. Mundy, X. Li, and H. Pyles, et al. 2021. "Quantifying the Dynamics of Protein Self-Organization Using Deep Learning Analysis of Atomic Force Microscopy Data." Nano Letters 21, no. 1:158-165. PNNL-SA-158524. doi:10.1021/acs.nanolett.0c03447 Cui W., X. Zhang, C.I. Pearce, Y. Chen, S. Zhang, W. Liu, and M.H. Engelhard, et al. 2019. "Cr(III) adsorption by cluster formation on boehmite nanoplates in highly alkaline solution." Environmental Science & Technology 53, no. 18:11043-11055. PNNL-SA-143650. doi:10.1021/acs.est.9b02693 Jiao F., X. Wu, T. Jian, S. Zhang, H. Jin, P. He, and C. Chen, et al. 2019. "Hierarchical Assembly of Peptoid-Based Cylindrical Micelles Exhibiting Efficient Resonance Energy Transfer in Aqueous Solution." Angewandte Chemie International Edition 58, no. 5:12223-12230. PNNL-SA-148211. doi:10.1002/anie.201904598 Pyles H., S. Zhang, J.J. De Yoreo, and D. Baker. 2019. "Controlling protein assembly on inorganic crystals through designed protein interfaces." Nature 571, no. 7764:251-256. PNNL-SA-142804. doi:10.1038/s41586-019-1361-6 Tuladhar A., Z.A. Jessamy-Chase, M.D. Baer, B.A. Legg, J. Tao, S. Zhang, and A.D. Winkelman, et al. 2019. "Direct Observation of the Orientational Anisotropy of Buried Hydroxyl Groups Inside Muscovite Mica." Journal of the American Chemical Society 141, no. 5:2135-2142. PNNL-SA-140259. doi:10.1021/jacs.8b12483 Chen J., E. Zhu, J. Liu, S. Zhang, Z. Lin, X. Duan, and H. Heinz, et al. 2018. "Building Two-Dimensional Materials One Row at a Time: Avoiding the Nucleation Barrier." Science 362, no. 6419:1135-1139. PNNL-SA-139351. doi:10.1126/science.aau4146 Jiang Z., S. Zhang, L. Hyldgaard Klausen, J. Song, Q. Li, Z. Wang, and B. Torger Stokke, et al. 2018. "In vitro single-cell dissection revealing the interior structure of cable bacteria." Proceedings of the National Academy of Sciences (PNAS) 115, no. 34:8517-8522. PNNL-SA-136014. doi:10.1073/pnas.1807562115 Liu L., S. Zhang, M.E. Bowden, J. Chaudhuri, and J.J. De Yoreo. 2018. "In Situ TEM and AFM Investigation of Morphological Controls during the Growth of Single Crystal BaWO4." Crystal Growth & Design 18, no. 3:1367-1375. PNNL-SA-132351. doi:10.1021/acs.cgd.7b01216 Ma X., S. Zhang, F. Jiao, C.J. Newcomb, Y. Zhang, A. Prakash, and Z. Liao, et al. 2017. "Tuning crystallization pathways through sequence-engineering of biomimetic polymers." Nature Materials 16, no. 7:767-774. PNNL-SA-123850. doi:10.1038/nmat4891