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个人简介

教育经历 2017.10-2019.10 University of Michigan, Ann Arbor | 生物医学工程 无 2014.9-2019.12 湖南大学 | 化学 | 博士 | 博士研究生毕业 2010.9-2014.6 湖南大学 | 化学 | 学士 | 大学本科毕业 工作经历 2022.12-至今 湘雅药学院 | 中南大学 2020.4-2022.12 化学化工学院 | 上海交通大学 博士后

研究领域

智能药物递送体系的构建和应用 DNA纳米技术在疾病诊断和治疗的应用

近期论文

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Hui Lv, Nuli Xie, Mingqiang Li, Mingkai Dong, Jiang Li, Xiaolei Zuo, Haibo Chen, Fei Wang*, Chunhai Fan*. Large-scale reconfigurable DNA-based logic gate for complex DNA computing. Nature 2023, 622, 292-300. (SCI一区) Zhenxiang Liu#, Nuli Xie#, Juan Li, Xiaoxiao Fu, Kemin Wang, Hui Shi*, Jin Huang*. Self-Priming DNA Polymerization-Propelled Stochastic Walkers on Magnetic Microbeads for Amplified Detection of miRNA. Anal. Chem. 2022, 95, 9, 4529-4535. (SCI一区) Nuli Xie, Huimin Wang, Xiaoxiao Fu, Jiaoli Wang, Jing Li, Kemin Wang, Jin Huang*. Dual amplification of bio-barcode and auto-cycling primer extension for highly sensitive detection of miRNA. Chem. Commun. 2022, 58, 73, 10221-10224. (SCI一区) Nuli Xie, Mingqiang Li, Yue Wang, Hui Lv, Jiye Shi, Jiang Li, Qian Li, Fei Wang*, Chunhai Fan. Scaling up multi-bit DNA full adder circuits with minimal strand displacement reactions. J. Am. Chem. Soc. 2022, DOI: 10.1021/jacs.2c03258. (SCI一区) Nuli Xie, Shiyuan Liu, Hongmei Fang, Yanjing Yang, Ke Quan, Jing Li, Xiaohai Yang, Kemin Wang, Jin Huang*. Three-dimensional molecular transfer from DNA nanocages to inner gold nanoparticle surfaces. ACS Nano 2019, 13, 4174-4182. (SCI一区) Nuli Xie, Haiyan Wang, Ke Quan, Feng Feng, Jin Huang*, Kemin Wang*. Self-assembled DNA-Based geometric polyhedrons: construction and applications. TrAC-Trends in Anal. Chem. 2020, 126, 115844. (SCI一区) Nuli Xie, Jin Huang*, Xiaohai Yang, Xiaoxiao He, Jianbo Liu, Jiaqi Huang, Hongmei Fang, Kemin Wang*. Scallop-inspired DNA nanomachine: a ratiometric nanothermometer for intracellular temperature sensing. Anal. Chem. 2017, 89, 12115-12122. (SCI一区) Nuli Xie, Jin Huang*, Xiaohai Yang, Yanjing Yang, Ke Quan, Min Ou, Hongmei Fang, Kemin Wang*. Competition-mediated FRET-switching DNA tetrahedron molecular beacon for intracellular molecular detection. ACS Sens. 2016, 12, 1445-1452. (SCI一区) Nuli Xie, Jin Huang*, Xiaohai Yang, Yanjing Yang, Ke Quan, He Wang, Le Ying, Min Ou, Kemin Wang*. A DNA tetrahedron-based molecular beacon for tumor-related mRNA detection in living cells. Chem. Commun. 2016, 52, 2346-2349. (SCI一区) Nuli Xie, Shiyuan Liu, Xiaohai Yang, Xiaoxiao He, Jin Huang*, Kemin Wang*. DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery. Analyst 2017, 142, 3322-3332. (SCI二区) Le Ying #, Nuli Xie#, Yanjing Yang, Xiaohai Yang, Qifeng Zhou, Bincheng Yin, Jin Huang*, Kemin Wang*. A cell-surface-anchored ratiometric i-motif sensor for extracellular pH detection. Chem. Commun. 2016, 52, 7818-7821. (SCI一区) Hongmei Fang#, Nuli Xie#, Min Ou, Jin Huang, Wenshan Li, Qing Wang, Jianbo Liu, Xiaohai Yang*, Kemin Wang*. Detection of nucleic acids in complex samples via magnetic microbead-assisted catalyzed hairpin assembly and “DD-A” FRET. Anal. Chem. 2018, 90, 7164-7170. (SCI一区) Jing Li, Jiaoli Wang, Shiyuan Liu, Nuli Xie, Ke Quan, Yanjing Yang, Xiaohai Yang, Jin Huang*, Kemin Wang*. Amplified FRET nanoflares: an endogenous mRNA‐powered nanomachine for intracellular microRNA imaging. Angew. Chem. Int. Ed. 2020, 132, 20104-20111. (SCI一区) Jesús Mosquera, Yuan Zhao, Hee‐Jeong Jang, Nuli Xie, Chuanlai Xu, Nicholas A. Kotov, Luis M. Liz‐Marzán*. Plamnonic nanoparticles with supramolecular recognition. Adv. Funct. Mater. 2019, 1902082. (SCI一区) Yanjing Yang, Jin Huang, Xiaohai Yang, Ke Quan, He Wang, Le Ying, Nuli Xie, Min Ou, Kemin Wang*. FRET nanoflares for intracellular mRNA detection: avoiding false positive signals and minimizing effects of system fluctuations. J. Am. Chem. Soc. 2015, 137, 8340-8343. (SCI一区) Ke Quan, Jing Li, Jiaoli Wang, Nuli Xie, Qiaomei Wei, Jinlu Tang, Xiaohai Yang, Kemin Wang, Jin Huang*. Dual-microRNA-controlled double-amplified cascaded logic DNA circuits for accurate discrimination of cell subtypes. Chem. Sci. 2019, 10, 1442-1449. (SCI一区)

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