Gutekunst, Will - Georgia Institute of Technology

个人简介

Education 2008 B.S. in Chemistry, University of Oklahoma 2013 Ph.D. in Organic Chemistry, The Scripps Research institute Employment 2022 – present Associate Professor, School of Chemistry and Biochemistry, Georgia Institute of Technology, School of Materials Science and Engineering (courtesy) 2016 – 2022 Assistant Professor, School of Chemistry and Biochemistry, Georgia Institute of Technology 2013 – 2016 NIH Postdoctoral Fellow with Professor Craig J. Hawker, University of California Santa Barbara 2008 – 2013 Graduate Student with Professor Phil S. Baran, The Scripps Research Institute Honors and Awards ACS PMSE Doolittle Award, 2022 3M Nontenured Faculty Award, 2020 Thieme Chemistry Journal Award, 2020 NIH Maximizing Investigators’ Research Award, 2019 Blanchard Professorship, 2019 ACS PMSE Young Investigator, 2019 ACS Petroleum Research Fund Doctoral New Investigator, 2018 NIH Ruth L. Kirschtein Postdoctoral Fellowship, 2013 BSF Travel Grant for Young Scientists, Prof. Doron Shabat – Tel Aviv University, 2013 Bristol-Myers Squibb Graduate Fellowship in Synthetic Organic Chemistry, 2013 Roche Excellence in Chemistry Award, 2012 NSF Predoctoral Fellowship, 2009

研究领域

The Gutekunst Lab is interested in pushing the limits of complexity in macromolecular systems using innovative concepts from synthetic organic chemistry. Specific projects in the lab will explore the design of novel monomers for the construction of functional polyamides, the development of small molecule reagents for the dynamic modulation of branched polymer architectures, and the investigation of new concepts for creating covalent bonds in challenging contexts. Each of these research projects will enable the generation of new functional materials with structures or assemblies that were previously inaccessible for study. Prospective students will obtain extensive training in synthetic organic chemistry, as well as polymer synthesis and characterization.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Xu, M.; Bullard, K. K.; Bacsa, J.; Gutekunst, W. R. Halide Abstraction-Mediated Synthesis of a Highly Twisted Amide. J. Org. Chem. 2024. Tran, V. T.; Ravn, A. K.; Rubel, C. Z.; Xu, M.; Fu, Y.; Wagner, E. M.; Wisniewski, S. R.; Liu, P.; Gutekunst, W. R.; Engle, K. M. Ni-catalysed dicarbofunctionalization for the synthesis of sequence-encoded cyclooctene monomers. Nat. Synth. 2024. Su, Y-L; Xiong, W.; Yue, L.; Paul, M. K.; Otte, K. S.; Basca, J.; Qi, H. J.; Gutekunst, W. R. Michael Addition–Elimination Ring-Opening Polymerization. J. Am. Chem. Soc. 2024, 146, 18074–18082. Su, Y-L.; Yue, L.; Tran, H.; Xu, M.; Engler, A.; Ramprasad, R.; Qi, H. J.; Gutekunst, W. R. Chemically Recyclable Polymer System Based on Nucleophilic Aromatic Ring-Opening Polymerization. J. Am. Chem. Soc. 2023. Sui, X.; Wang, C.; Gutekunst, W.R. Sequestration of ruthenium residues via efficient fluorous-enyne termination. Polymer Chemistry. 2023. Stellmach, K.A.; Paul, M.K.; Xu, M.; Su, Y.; Fu, L.; Toland, A.R.; Tran, H.; Chen, L.; Ramprasad, R.; Gutekunst, W.R. Modulating Polymerization Thermodynamics of Thiolactones Through Substituent and Heteroatom Incorporation. ACS Macro Letters. 2022, 11, 895-901. Sui, X.; Gutekunst, W.R. Cascade Alternating Metathesis Cyclopolymerization of Diynes and Dihydrofuran. ACS Macro Letters. 2022, 11, 630-635. Zhang, T.; Sui, X.; Gutekunst, W.R. Convergent Synthesis of Branched Metathesis Polymers with Enyne Reagents. Macromolecules. 2021, 54, 8435-8442. Xu, M.; Paul, M. K.; Bullard, K. K.; DuPre, C.; Gutekunst, W.R. Modulating Twisted Amide Geometry and Reactivity Through Remote Substituent Effects. J. Am. Chem. Soc. 2021, 143, 14657-14666. Bamford, J. T.; Smith, R. A.; Leng, C. Z.; Gutekunst, W. R.; Losego, M. D. Measuring the Glass Transition Temperature of Vapor-Phase-Infiltrated AlOx-PS-r-PHEMA Organic–Inorganic Hybrid Thin-Film Materials. Macromolecules. 2021, 54, 6790-6798. Yi, D.; Acharya, A.; Gumbart, J. C.; Gutekunst, W. R.; Agarwal, V. Gatekeeping Ketosynthases Dictate Initiation of Assembly Line Biosynthesis of Pyrrolic Polyketides. J. Am. Chem. Soc. 2021, 143, 7617-7622. Marks, M. A.; Kalaitzidou, K.; Gutekunst, W. R. Synthesis and Characterization of Cationic Dendrimer-PDMS Hybrids. Macromol. Rapid Commun. 2020, 2000652. Bullard, K. K.; Srinivasarao, M.; Gutekunst, W. R. Modification of Cellulose Nanocrystal Surface Chemistry with Diverse Nucleophiles for Materials Integration. J. Mater. Chem. A, 2020, 8, 18024-18031. Sui, X.; Zhang, T.; Pabarue, A. B.; Gutekunst, W. R. Alternating Cascade Metathesis Polymerization of Enynes and Cyclic Enol Ethers with Active Ruthenium Fischer Carbenes. J. Am. Chem. Soc. 2020, 142, 12942–12947. Levi, A. E.; Fu, L.; Lequieu, J.; Horne, J. D.; Blankenship, J.; Mukherjee, S.; Zhang, T.; Fredrickson, G. H.; Gutekunst, W. R.; Bates, C. M. Efficient Synthesis of Asymmetric Miktoarm Star Polymers. Macromolecules, 2020, 53, 2, 702–710. Fu, L.; Sui, X.; Crolais, A. E.; Gutekunst, W. R. Modular Approach to Degradable Acetal Polymers Using Cascade Enyne Metathesis Polymerization. Angew. Chem. Int. Ed. 2019, 58, 15726-15730. Xu, M.; Bullard, K. K.; Nicely, A. M.; Gutekunst, W. R. Resonance promoted ring-opening metathesis polymerization of twisted amides. Chem. Sci., 2019, 10, 9729-9734. Zhang, T.; Gutekunst, W. R. Pulsed-addition ring-opening metathesis polymerization with functional enyne reagents. Polym. Chem. 2020, 11, 259-264. Balding P.; Cueto, R.; Russo, P. S.; Gutekunst, W. R. Synthesis of Perfectly Sulfonated Sodium Polystyrene Sulfonate over a Wide Molar Mass Range via Reversible-Deactivation Radical Polymerization. J. Polym. Sci., Part A: Polym. Chem. 2019, 57, 1527-1537. Fu, L.; Xu, M.; Yu, J.; Gutekunst, W. R. Halide-Rebound Polymerization of Twisted Amides. J. Am. Chem. Soc. 2019, 141, 2906-2910. Smith, R. A.; Fu, G.; McAteer, O.; Xu, M.; Gutekunst, W. R. A Radical Approach to Thioester-Containing Polymers. J. Am. Chem. Soc. 2019, 141, 1446-1451. Fu, L. ; Zhang, T.; Fu, G.; Gutekunst, W. R. Relay Conjugation of Living Metathesis Polymers. J. Am. Chem. Soc. 2018, 140, 12181-12188. Zhang, T. ; Fu, L. ; Gutekunst, W. R. Practical Synthesis Of Functional Metathesis Initiators Using Enynes. Macromolecules. 2018, 51, 6496–6503. Lunn, D. J.; Discekici, E. H.; Read de Alaniz, J.; Gutekunst, W. R.; Hawker, C. J. Established and Emerging Strategies for Polymer Chain-End Modification. Journal of Polymer Science Part A: Polymer Chemistry2017, 55, 2903-2914. Ren, J. M.; Lawrence, J.; Knight, A. S.; Abdilla, A.; Zerdan, R. B.; Levi, A. E.; Oschmann, B.; Gutekunst, W. R.; Lee, S.; Li, Y.; McGrath, A. J.; Bates, C. M.; Qiao, G. G.; Hawker, C. J. Controlled Formation and Binding Selectivity of Discrete Olig(methylmethacrylate) Stereocomplexes.J. Am. Chem. Soc.2018, 140, 1945-1951 Kaminker, R.; Anastasaki, A.; Gutekunst, W. R.; Luo, Y.; Lee, S.; Hawker, C. J. Tunning Of Protease Resistance In Oligopeptides Through N-alkylation.Chem. Commun,2018, 54, 9631-9634. Kaminker, R.; Kaminker, I.; Gutekunst, W. G.; Luo, Y.; Lee, S.; Niu, J.; Han, S.; Hawker, C. J. Tuning Conformation And Properties Of Peptidomimetic Backbones Through Dual N/Cα-Substitution. Chem. Commun. 2018, 54, 5237-5240.