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个人简介

教育背景 2008-2013 南开大学 理学博士(有机化学) 导师:周其林院士 2004-2008 河北大学 理学学士(材料化学) 工作履历 2016-2021 伊利诺伊大学芝加哥分校(UIC) 博士后 2013-2016 帝国理工学院 博士后

研究领域

金属有机化学、过渡金属催化、不对称催化、天然产物及手性药物分子合成等

近期论文

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Jiang, D.; Li, X.; Xiao, M.; Cheng, L.-J.* Cobalt-Catalyzed Intramolecular Markovnikov Hydrocarbonylation of Unactivated Alkenes via Hydrogen Atom Transfer. Angew. Chem. Int. Ed. 2024, e202412828. Li, W.; Wang, C.; Xiao, M.; Cheng, L.-J.* Copper-Catalyzed Protoarylation of gem-Difluoroallenes. Org. Lett. 2024, 26, 525–529. Li, W.; Jiang, D.; Wang, C.; Cheng, L.-J.* Recent Advances in Base-Metal-Catalyzed Carbonylation of Unactivated Alkyl Electrophiles. Chin. J. Chem. 2023, 41, 3419–3432. Cheng, L.-J.*; Mankad, N. P.* Copper-Catalyzed Carbonylative Coupling of Alkyl Halides. Acc. Chem. Res. 2021, 54, 2261–2274. Cheng, L.-J.; Zhao, S.; Mankad, N. P.* One-Step Synthesis of Acylboron Compounds via Cu-Catalyzed Carbonylative Borylation of Alkyl Halides. Angew. Chem. Int. Ed. 2021, 60, 2094–2098. Cheng, L.-J.; Mankad, N. P.* C-C and C-X Coupling Reactions of Unactivated Alkyl Electrophiles Using Copper Catalysis. Chem. Soc. Rev. 2020, 49, 8036–8064. Cheng, L.-J.; Mankad, N. P.* Cu-Catalyzed Carbonylative Silylation of Alkyl Halides: Efficient Access to Acylsilanes. J. Am. Chem. Soc. 2020, 142, 80–84. Cheng, L.-J.; Mankad, N. P.* Heterobimetallic Control of Regioselectivity in Alkyne Hydrostannylation: Divergent Syntheses of α- and (E)-β-Vinylstannanes via Cooperative Sn-H Bond Activation. J. Am. Chem. Soc. 2019, 141, 3710–3716. Cheng, L.-J.; Mankad, N. P.* Cu-Catalyzed Borocarbonylative Coupling of Internal Alkynes with Unactivated Alkyl Halides: Modular Synthesis of Tetrasubstituted β-Borylenones, Angew. Chem. Int. Ed. 2018, 57, 10328–10332. Cheng, L.-J.; Islam, S. M.; Mankad, N. P.* Synthesis of Allylic Alcohols via Cu-Catalyzed Hydrocarbonylative Coupling of Alkynes with Alkyl Halides, J. Am. Chem. Soc. 2018, 140, 1159–1164. Cheng, L.-J.; Brown, A. P. N.; Cordier, C. J.* From Propargylic Fluorinations to [1,3]-Rearrangements: Anion and Ligand Effects in Cu-Acetylide Chemistry. Synlett. 2018, 29, 1675–1682. Cheng, L.-J.; Mankad, N. P.* Cu-Catalyzed Hydrocarbonylative C–C Coupling of Terminal Alkynes with Alkyl Iodides, J. Am. Chem. Soc. 2017, 139, 10200–10203. Pye, D. Cheng, L.-J. Mankad, N. P.* Cu/Mn Bimetallic Catalysis Enables Carbonylative Suzuki–Miyaura Coupling with Unactivated Alkyl Electrophiles, Chem. Sci. 2017, 8, 4750–4755. Cheng, L.-J.; Brown, A. P. N.; Cordier, C. J.* Enantioselective Propargylic [1,3]-Rearrangements: Copper-catalyzed O-to-N Migrations toward C–N Bond Formation, Chem. Sci. 2017, 8, 4299–4305. Adeleke, A. F.; Brown, A. P. N., Cheng, L.-J.; Mosleh, K. A. M.; Cordier, C. J.* Recent Advances in Catalytic Transformations Involving Copper Acetylides, Synthesis 2017, 49, 790–801. Liu, Y.#; Cheng, L.-J. #; Yue, H.-T.; Che, W.; Xie, J.-H.*; Zhou, Q.-L. Divergent Enantioselective Synthesis of Hapalindole-Type Alkaloids Using Catalytic Asymmetric Hydrogenation of a Ketone to Construct the Chiral Core Structure, Chem. Sci. 2016, 7, 4725–4729 (#co-first author). Cheng, L.-J.; Cordier, C. J.* Catalytic Nucleophilic Fluorination of Secondary and Tertiary Propargylic Electrophiles with a Copper–N-Heterocyclic Carbene Complex, Angew. Chem. Int. Ed. 2015, 54, 13734–13738. Cheng, L.-J.; Xie, J.-H.*; Chen, Y.; Wang, L.-X.; Zhou, Q.-L.* Enantioselective Total Synthesis of (−)-Δ8-THC and (−)-Δ9-THC via Catalytic Asymmetric Hydrogenation and SNAr Cyclization, 
Org. Lett. 2013, 15, 764–767. Huang, K.-L.; Guo, G.; Cheng, L.-J.; Xie, L.-G.; Zhou, Q.-L.; Xu, X.-H.*; Zhu, S.-F.* Enantioselective Palladium-Catalyzed Ring-Opening Reaction of Azabenzonorbornadienes with Methyl 2-Iodobenzoate: An Efficient Access to cis-Dihydrobenzo[c]phenanthridinone, Adv. Synth. Catal. 2013, 355, 2833–2838. Cheng, L.-J.; Xie, J.-H.*; Wang, L.-X.; Zhou, Q.-L.* Enantioselective Synthesis of (−)-CP-55940 via Ruthenium-Catalyzed Asymmetric Hydrogenation of Ketone, Adv. Synth. Catal. 2012, 354, 1105–1113.

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