Wendlandt, Alison E. - Massachusetts Institute of Technology

个人简介

Education Harvard University NIH Postdoctoral Fellow (2015-2018) Advisor: E. N. Jacobsen University of Wisconsin – Madison Ph.D. Chemistry (2015) Advisor: S. S. Stahl University of Chicago B.S. Chemistry; Biological Chemistry (2007) Advisor: S. Kozmin

研究领域

design of new catalysts and catalytic transformations identification of important applications for selective catalytic processes elucidation of new mechanistic principles to expand powerful existing catalytic reaction manifolds

近期论文

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Wendlandt A. E., Vangal, P., Jacobsen, E. N. “Quarternary Stereocentres via an Enantioconvergent Catalytic SN1 Reaction” Nature, 2018, 556, 447-451. Kwiatkowski, S., Sviripa, V. M., Zhang, Z., Wendlandt, A. E., Hobartner, C., Watt, D. S., Stamm, S. "Synthesis of a Norcantharidin-Tethered Guanosine: Protein phosphatase-1 inhibitors that change alternative splicing" Bioorg. Med. Chem. Lett. 2016, 26, 965-968. Wendlandt, A. E., Stahl, S. S. “Quinone-Catalyzed Selective Oxidation of Organic Molecules" Angew. Chem. Int. Ed. 2015, 54, 14638-14658. Wendlandt, A. E., Stahl, S. S. “Modular o-Quinone Catalyst System for Dehydrogenation of Tetrahydroquinolines under Ambient Conditions" J. Am. Chem. Soc. 2014, 136, 11910-11913. Wendlandt, A. E., Stahl, S. S. “Bioinspired Aerobic Oxidation of Secondary Amines and Nitrogen Heterocycles with a Bifunctional Quinone Catalyst” J. Am. Chem. Soc. 2014, 136, 506-512. Wendlandt, A. E., Stahl, S. S. “Chemoselective Organocatalytic Aerobic Oxidation of Primary Amines to Secondary Imines” Org. Lett. 2012, 14, 2850-2853. Wendlandt, A. E., Stahl, S.S. “Copper(II)-Mediated Oxidative Cyclization of Enamides to Oxazoles” Org. Biomol. Chem. 2012, 10, 3866-3870. Wendlandt, A. E., Suess, A. M., Stahl, S.S. “Copper-Catalyzed Aerobic Oxidative C-H Functionalizations: Trends and Mechanistic Insights” Angew. Chem. Int. Ed. 2011, 50, 11062-11087. Zhang, Z., Kelemen, O., van Santen, M. A., Yelton, S.M., Wendlandt, A. E., Sviripa, V. M., Bollen, M., Beullens, M., Urlaub, H., Lührmann, R. Watt, D.S., Stamm, S. “Synthesis and Characterization of Pseudocantharidins, Novel Phosphatase Modulators that Promote the Inclusion of Exon 7 into the SMN (Survival of Motorneuron) Pre-mRNA” J. Biol. Chem. 2011, 286, 10126-10136. Wendlandt, A. E., Yelton, S. M., Lou, D., Watt, D.S., Noonan, D. J. “Synthesis and Functional Analysis of Novel Bivalent Estrogens” Steroids 2010, 75, 825-833.