Miller , Gavin - Keele University - School of Physical and Geographical Sciences, Chemistry and Medicinal Chemistry

个人简介

Gavin returned to academia and the University of Manchester in 2009, firstly as a PDRA in the Manchester Institute of Biotechnology developing chemical synthesis approaches to heparan sulfate oligosaccharides and secondly as a fixed-term lecturer, in 2013, within the School of Chemistry. He took up his current lectureship in chemistry at Keele in 2015.

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Miller GJ, Hansen SU, Avizienyte E, Rushton G, Cole C, Jayson GC, Gardiner JM. 2013. Efficient chemical synthesis of heparin-like octa-, deca- and dodecasaccharides and inhibition of FGF2-and VEGF(165)-mediated endothelial cell functions. CHEMICAL SCIENCE, vol. 4(8), 3218-3222. link> doi> full text> Hansen SU, Miller GJ, Cliff MJ, Jaysonc GC, Gardiner JM. 2015. Making the longest sugars: a chemical synthesis of heparin-related [4](n) oligosaccharides from 16-mer to 40-mer. CHEMICAL SCIENCE, vol. 6(11), 6158-6164. link> doi> full text> Takemoto N, Suehara T, Frisco HL, Sato S-I, Sezaki T, Kusamori K, Kawazoe Y, Park SM, Yamazoe S, Mizuhata Y, Inoue R, Miller GJ, Hansen SU, Jayson GC, Gardiner JM, Kanaya T, Tokitoh N, Ueda K, Takakura Y, Kioka N, Nishikawa M, Uesugi M. 2013. Small-Molecule-Induced Clustering of Heparan Sulfate Promotes Cell Adhesion. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 135(30), 11032-11039. link> doi> Jayson GC, Hansen SU, Miller GJ, Cole CL, Rushton G, Avizienyte E, Gardiner JM. 2015. Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology. CHEMICAL COMMUNICATIONS, vol. 51(72), 13846-13849. link> doi> full text> Hansen SU, Miller GJ, Cole C, Rushton G, Avizienyte E, Jayson GC, Gardiner JM. 2013. Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies. NATURE COMMUNICATIONS, vol. 4, Article ARTN 2016. link> doi>