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个人简介

耿轶群,研究员,助理教授,博士生导师。先后于北京大学药学院获得药学学士(2005)和化学生物学博士学位(2011)。2011-2019年在德国康斯坦茨大学化学系和英国牛津大学化学系从事博士后研究工作。2020年入选海外高层次人才引进计划青年项目,加入中国医学科学院药物研究所担任课题组长。兼任中国化学会糖化学专业委员会、中国生物物理学会糖生物学分会和中国疫苗行业协会糖疫苗专业委员会委员,及北京国际医药促进会理事。

研究领域

1. 糖化学和化学糖生物学 2. 糖代谢重塑相关疾病的机制和干预策略 3. 基于内源性活性物质的创新药物发现

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Tian Li, Anhui Wang, Yanling Zhang, Wei Chen, Yanshen Guo, Xia Yuan, Yuan Liu, Yiqun Geng*. Chemoproteomic Profiling of Signaling Metabolite Fructose-1,6-Bisphosphate Interacting Proteins in Living Cells. J. Am. Chem. Soc. 2024, 146, 15155−15166. Tianlu Li*, Tong Li, Yue Yang, Haoru Zhuang, Jianwu Lv, Ning Zhou, Miaomiao Zhang, Fengshan Wang, Yiqun Geng*, Richard R. Schmidt*, Peng Peng*. Concise Synthesis of Lactococcus garvieae Lipoteichoic Acids through an Additive Modulated Preactivation Protocol and the Immunological Studies. CCS Chem. 2024, 6, 403−414. Yingxin Shi#, Sheng Yan#, Guang-Can Shao#, Jinglong Wang, Yong-Ping Jian, Bo Liu, Yanqiu Yuan, Ke Qin, Shanshan Nai, Xiahe Huang, Yingchun Wang, Zhenghui Chen, Xing Chen, Meng-Qiu Dong, Yiqun Geng*, Zhi-Xiang Xu*, Jing Li*. O-GlcNAcylation stabilizes the autophagy-initiating kinase ULK1 by inhibiting chaperone-mediated autophagy upon HPV infection. J. Biol. Chem. 2022, 298, 102341. Cara A. Griffiths#, Ram Sagar#, Yiqun Geng#, Lucia F. Primavesi, Mitul K. Patel, Melissa K. Passarelli, Ian S. Gilmore, Rory T. Steven, Josephine Bunch, Matthew J. Paul*, Benjamin G. Davis*. Chemical intervention in plant sugar-signalling increases yield and resilience. Nature 2016, 540, 574−578. Yiqun Geng#, Amit Kumar#, Hassan M. Faidallah, Hassan A. Albar, Ibrahim, A. Mhkalid, Richard R. Schmidt*. Cooperative Catalysis in Glycosidation Reactions with O-Glycosyl Trichloroacetimidates as Glycsoyl Donors. Angew. Chem. Int. Ed. 2013, 52, 10089−10092.

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