莫一鸣 - 浙江大学 - 化学工程与生物工程学院

个人简介

2014年本科毕业于清华大学化学工程系，被评为优秀毕业生（64/3200+）；随后直博进入MIT化学工程系师从美国两院院士Klavs F. Jensen，于2019年获得博士学位；博士毕业后在MIT进行博士后深造。主要研究为以医药制造与研发为中心的多领域交叉科研，包括电化学医药中间体合成、流动化学、高通量筛选、化学人工智能等。

研究领域

电化学有机合成：精细化学品与医药中间体流动化学与微流控无人高通量筛选体系的构建与人工智能

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Scalable decarboxylative trifluoromethylation by ion-shielding heterogeneous photoelecs trocatalysis Yixin Chen†, Yuchen He†, Yong Gao†, Jiakun Xue, Wei Qu, Jun Xuan*, Yiming Mo* Science, 2024, 384(6696):670-676. DOI: 10.1126/science.adm8902 Wireless Electrochemical Reactor for Accelerated Exploratory Study of Electroorganic Synthesis J. Chen, Y. Mo* ACS Central Science, 2023, accepted. DOI: 10.1021/acscentsci.3c00856 Accelerated Electrosynthesis Development Enabled by High-Throughput Experimentation H. Chen, Y. Mo* Synthesis, 2023, 55, 2817–2832. DOI: 10.1055/a-2072-2617 AROPS: A Framework of Automated Reaction Optimization with Parallelized Scheduling. Journal of Chemical Information and Modeling Y. Ruan, S. Lin, Y. Mo* Journal of Chemical Information and Modeling, 2023, accepted. DOI: Machine-Learning-Guided Discovery of Electrochemical Reactions A. F. Zahrt, Y. Mo, K. Y. Nandiwale, R. Shprints, E. Heid, K. F. Jensen* Journal of the American Chemical Society, 2022, 44, 22599–22610. DOI: 10.1021/jacs.2c08997 Machine-Learning-Assisted Exploration of Anion-Pillared Metal Organic Frameworks for Gas Separation J. Hu, J. Cui, B. Gao, L. Yang, Q. Ding, Y. Li, Y. Mo, H. Chen, X. Cui, H. Xing* Matter, 2022, 5, 3901–3911. DOI: 10.1016/j.matt.2022.07.029 Autonomous high-throughput screening technology for accelerating drug molecule discovery and synthesis (智能高通量筛选技术加速医药小分子合成) J. Chen#, X. Zheng#, Y. Ruan#, Y. Mo* SCIENTIA SINICA Chimica (中国科学: 化学), 2023, 53, 79–94. DOI: 10.1360/SSC-2022-0101 Continuous Stirred-Tank Reactor Cascade Platform for Self-Optimization of Reactions Involving Solids K. Y. Nandiwale, T Hart, A. F. Zahrt, A. M. K. Nambiar, P. T. Mahesh, Y. Mo, M. J. Nieves-Remacha, M. D. Johnson, P. García-Losada, C. Mateos, J. A. Rincón, K. F. Jensen* Reaction Chemistry & Engineering, 2022, Accepted. DOI: 10.1039/D2RE00054G Promotional Synergistic Effect of Fine-tuned Mordenite: Overcoming the Selectivity Limitations of Naphthalene Alkylation with Tert-butyl Alcohol M. Cai, X. Wang,* Y. Mo, Y. Chen, L. Dai* Microporous and Mesoporous Materials, 2022, 333, 111725. DOI: 10.1016/j.micromeso.2022.111725 A Scalable Light-diffusing Photochemical Reactor for Continuous Processing of Photoredox Reactions J. Zhang, Y. Mo* Chemical Engineering Journal, 2022, 435, 134889. DOI: 10.1016/j.cej.2022.134889 Continuous-Flow Microreactor-Enhanced Clean NAD+ Regeneration for Biosynthesis of 7‑Oxo-lithocholic Acid H. Li, Z. You, Y. Liu, G. Zheng, H. Gong, Y. Mo, N. Zhu, Y. Bai*, and J. Xu* ACS Sustainable Chemistry & Engineering, 2022, 10(1), 456–463. DOI: 10.1021/acssuschemeng.1c06730 Photoredox Iridium–Nickel Dual Catalyzed Cross-Electrophile Coupling: From a Batch to a Continuous Stirred-Tank Reactor via an Automated Segmented Flow Reactor R. Duvadie, A. Pomberger, Y. Mo, E. I. Altinoglu, H. Hsieh, K. Y. Nandiwale, V. L. Schultz, K. F. Jensen*, R. I. Robinson* Organic Process Research & Development, 2021, 25, 10, 2323–2330. DOI: 10.1021/acs.oprd.1c00251 A High-Temperature Continuous Stirred-Tank Reactor Cascade for the Multistep Synthesis of InP/ZnS Quantum Dots I. Lignos, Y. Mo, L. Carayannopoulos, M. Ginterseder, M. G. Bawendi, K. F. Jensen* Reaction Chemistry & Engineering, 2021, 6, 459-464. DOI: 10.1039/D0SC05078D Evaluating and Clustering Retrosynthesis Pathways with Learned Strategy Y. Mo†, Y. Guan†, P. Verma, J. Guo, M. E. Fortunato, Z. Lu, C. W. Coley, K. F. Jensen* Chemical Science, 2021, 12, 1469–1478. DOI: 10.1039/D0SC05078D Towards Efficient Discovery of Green Synthesis Pathways with Monte Carlo Tree Search and Reinforcement Learning X. Wang, Y. Qian, H. Gao, C. W. Coley, Y. Mo, R. Barzilay, K. F. Jensen* Chemical Science, 2020, 11(40), 10959-10972. DOI: 10.1039/D0SC04184J Multifunctional Microfluidic Platform for High-throughput Experimentation of Electroorganic Chemistry Y. Mo, G. Rughoobur, A. M. K. Nambiar, K. Zhang, K. F. Jensen* Angewandte Chemie International Edition, 2020, 59 (47), 20890-20894. DOI: 10.1002/anie.202009819 Microfluidic Electrochemistry for Single-electron Transfer Redox-neutral Reactions Y. Mo†, Z. Lu†, G. Rughoobur, P. Patil, N. Gershenfeld, A. I. Akinwande, S. L. Buchwald*, K. F. Jensen* Science, 2020, 368, 1352–1357 DOI: 10.1126/science.aba3823 Continuous Flow Suzuki–Miyaura Couplings in Water under Micellar Conditions in a CSTR Cascade Catalyzed by Fe/ppm Pd Nanoparticles A. B. Wood†, K. Y. Nandiwale†, Y. Mo, B. Jin, A. Pomberger, V. L. Schultz, F. Gallou, K. F. Jensen*, B. H. Lipshutz* Green Chemistry, 2020, 22 (11), 3441–3444 DOI: 10.1039/D0GC00378F. A Continuous Stirred-tank Reactor (CSTR) Cascade for Handling Solid-containing Photochemical Reactions A. Pomberger, Y. Mo, K. Y. Nandiwale, V. L. Schultz, R. Duvadie, R. I. Robinson, E. I. Altinoglu, and K. F. Jensen* Organic Process Research & Development, 2019, 23 (12), 2699–2706 DOI: 10.1021/acs.oprd.9b00378. Adding Crystals to Minimize Clogging in Continuous Flow Synthesis G. Giri, L. Yang, Y. Mo, and K. F. Jensen* Crystal Growth & Design, 2019, 19 (1), 98–105 DOI: 10.1021/acs.cgd.8b00999. Scalable Thin-layer Membrane Reactor for Heterogeneous and Homogeneous Catalytic Gas-liquid Reactions Y. Mo†, J. Imbrogno†, H. Zhang, K. F. Jensen* Green Chemistry, 2018, 20 (16), 3867–3874 DOI: 10.1039/C8GC01917G. Continuous NHPI-mediated Electrochemical Aerobic Oxidation of Benzylic C-H Bonds Y. Mo, K. F. Jensen* Chemistry–A European Journal, 2018, 24 (40), 10260–10265 DOI: 10.1002/chem.201802588. High-Performance Miniature CSTR for Biphasic C-C Bond-forming Reactions Y. Mo, H. Lin, K. F. Jensen* Chemical Engineering Journal, 2018, 335, 936–944 DOI: 10.1016/j.cej.2017.10.114. A Miniature CSTR Cascade for Continuous Flow of Reactions Containing Solids Y. Mo, K. F. Jensen* Reaction Chemistry & Engineering, 2016, 1 (5), 501–507 DOI: 10.1039/C6RE00132G.