李文军 - 青岛大学

个人简介

副教授，青岛大学特聘教授，泰山学者青年专家，硕士研究生导师，山东省优青。2006年本科毕业于郑州大学制药工程专业，获工学学士学位；2011年研究生毕业于华东理工大学药物化学专业，获医学博士学位。2012年01月至2015年06月分别在新加坡国立大学、南洋理工大学和清华大学从事博士后研究，博士及博士后期间主要从事有机小分子催化领域的研究。2015年7月受聘于青岛大学药学院，担任不对称催化与药物合成团队负责人。

研究领域

有机合成化学：开展高选择性、高效经济、环境友好的合成方法学研究药物合成化学：应用有机催化的方法合成活性药物分子并进行活性研究过程化学：手性药物及中间体、天然药物的合成新方法研究及其过程化学开发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Ziyang Wang, Xiao Lin, Xuling Chen, Pengfei Li,*Wenjun Li*. Organocatalytic Stereoselective 1,6-Addition of Thiolacetic Acids to Alkynyl Indole Imine Methides: Access to Axially Chiral Sulfur-containing Tetrasubstituted Allenes.Org. Chem. Front.,2021,8, 3469-3474. (IF = 5.28) FushuaiLi, Zhihong Yang,Yanyan Yang,Qiuhong Huang,Xuling Chen,Pengfei Li,*Mingxin Dong,*Wenjun Li*.OrganocatalyticEnantioselectiveaza-Michael Addition of Arylaminesto 7-Methide-7H-indoles.Adv. Synth. Catal.2021,363, 2557-2561. (IF = 5.85) Fushuai Li, Shuai Liang,Yepeng Luan,Xuling Chen,Hanhui Zhao, Anqi Huang,Pengfei Li,*Wenjun Li*.OrganocatalyticRegio-,Diastereo- andEnantioselective γ-Additions ofIsoxazol-5(4H)-ones to β,γ-Alkynyl-α-iminoEsters for theSynthesis ofAxiallyChiralTetrasubstituted α-AminoAllenoates.Org. Chem. Front.,2021,8,1243-1248. (IF = 5.28) Fushuai Li, Xuling Chen,Shuai Liang, Zhenyan Shi, Pengfei Li,*Wenjun Li*.OrganocatalyticSite- andStereoselective1,6-Additions ofN-aryl-3-oxobutanamides toPropargylic aza-p-Quinone methides.Org. Chem. Front.,2020,7, 3446-3451. (IF = 5.15) Qianqian Song, Pei Zhang, Shuai Liang, Xuling Chen, Pengfei Li,*Wenjun Li*.Organocatalytic Regio- and Enantioselective 1,8-Additions ofNitrogen and Sulfur Nucleophiles to 6‑Methylene‑6H‑indoles.Org. Lett.,2020,22, 7859-7863. (IF = 6.56) Ziyang Wang, Anqi Huang, Fang Fang, Pengfei Li,* Guokai Liu,*Wenjun Li*.Non-hydrogenBondCatalyst-mediatedDiastereoselectiveConjugateAdditions of 5H-oxazol-4-ones too-Hydroxyphenyl-substitutedp-QuinoneMethides.Org. Biomol. Chem.,2020,18, 6807-6811. (IF = 3.49) Anqi Huang, Xing Guo, Pengfei Li,*Wenjun Li*.Recent Advances in Catalytic Asymmetric Reactions ofThiazolones, Rhodanines and Their Derivatives.Adv. Synth. Catal.2020,362, 3542-3557. (IF = 5.85) Xiao Lin, Fang Fang, Wei Lin, Zhantao Liu, Xiaoyong Chang, Pengfei Li,*Wenjun Li*.Organocatalytic Enantioselective α-Amination by ConjugateAddition of 5H-Thiazol-4-ones to Arylazocarboxylates: Access toChiralN,S-acetals.Asian J. Org. Chem.2020,9, 1187-1191. (IF = 3.13) Chen Zhang, Yuyu Cheng, Fushuai Li, Yepeng Luan, Pengfei Li*,Wenjun Li*.Organocatalytic Enantioselective RegiodivergentC-H BondFunctionalization of 1-Naphthols with 1-Azadienes.Adv. Synth. Catal.2020,362, 1286-1291. (IF = 5.85) Huijun Yuan,Yao Li, Hanhui Zhao, Zhihong Yang, Xin Li*,Wenjun Li*.AsymmetricSynthesis ofAtropisomericPyrazoleviaanEnantioselectiveReaction ofAzonaphthalene withPyrazolone.Chem. Commun.,2019,55, 12715-12718.(IF =6.16) Chen Zhang, Xinye Shang, Yuyu Cheng, Fushuai Li, Hanhui Zhao,Pengfei Li*,Wenjun Li*.EnantioselectiveConstruction of 3-Substituted3-amino-2-oxindolesContaining anN,N-ketalSkeleton viaOrganocatalyzedAza-addition ofIsatinImines.Org. Biomol. Chem.,2019,17,8374-8378. (IF = 3.49) Lili Zhang, Yuzhe Han, Anqi Huang, Pei Zhang, Pengfei Li*,Wenjun Li*.Organocatalytic Remote Stereocontrolled 1,8-Additions ofThiazolones to Propargylic Aza‑p‑quinone Methides.Org. Lett.,2019,21, 7415-7419. (IF = 6.56) Hanhui Zhao, Huijun Yuan, Yanru Zhang, Rongshi Li*,Wenjun Li*.Enamine Catalytic Annulation of Azonaphthalenes: An Access toIndole Derivatives.Org. Lett.,2019,21, 6557-6561. (IF = 6.56) Yipeng Luan, Anqi Huang, Yuyu Cheng, Xiaohong Liu, Pengfei Li*,WenjunLi*.Organocatalytic Enantioselective Michael Addition ofOxazolones to 2-EnoylpyridineN-Oxides for Assembling ofPyridineN-Oxides Featuring Vicinal Oxygen-containingTetrasubstituted Stereocenters.Adv. Synth. Catal.2019,361, 4208-4214. (IF = 5.45) Wei Lin, Xiao Lin, Yuyu Cheng, Xiaoyong Chang, San Zhou, Pengfei Li*,Wenjun Li*.OrganocatalyticEnantioselectiveDirectVinylogousMichaelAddition of γ-SubstitutedDeconjugateButenolides toAzadienes.Org. Chem. Front.,2019,6, 2452-2456. (IF = 5.08) Pei Zhang, Qiuhong Huang, Yuyu Cheng, Rongshi Li*, Pengfei Li*,Wenjun Li*. Remote Stereocontrolled Construction of Vicinal Axially Chiral Tetrasubstituted Allenes and Heteroatom-Functionalized Quaternary Carbon Stereocenters.Org. Lett.,2019,21, 503-507. (高被引论文,IF = 6.49) Pengfei Zhang, Xing Guo, Chang Liu,Wenjun Li*, Pengfei Li*. Enantioselective Construction of PyridineN-Oxides Featuring 2,3-Dihydrofuran Motifs via Phosphine-Catalyzed [4 + 1]-Annulation of 2-EnoylpyridineN-Oxides with Morita-Baylis-Hillman Carbonates.Org. Lett.,2019,21, 152-155. (IF = 6.49) Anqi Huang, Lili Zhang, Dongmei Li, Yidong Liu*, Hailong Yan*,Wenjun Li*. Asymmetric One-Pot Construction of Three Stereogenic Elements: Chiral Carbon Center, Stereoisomeric Alkenes, and Chirality of Axial Styrenes.Org. Lett.,2019,21, 95-99. (IF = 6.49) Wei Lin, Chen Zhang, Wen Xu, Yuyu Cheng, Pengfei Li*,Wenjun Li*.Organocatalytic Asymmetric Michael Addition of Rhodanines to Azadienes for Assembling of Sulfur-containing Tetrasubstituted Carbon Stereocenters.Adv. Synth. Catal.2019,361, 476-480. (IF = 5.12) Kun Liu, Xinye Shang, Yuyu Cheng, Xiaoyong Chang, Pengfei Li*,Wenjun Li*. Regioselective [3 + 2]-annulation of Hydrazonyl Chlorides with 1,3-Dicarbonyl Compounds for Assembling of Polysubstituted Pyrazoles.Org. Biomol. Chem.,2018,16, 7811-7814. (IF = 3.42) Qiuhong Huang, Yuyu Cheng, Huijun Yuan, Xiaoyong Chang, Pengfei Li*,Wenjun Li*.Organocatalytic Enantioselective Mannich-Type Addition of 5H-thiazol-4-ones to Isatin-derived Imines: Access to 3-Substituted 3-amino-2-oxindoles Featured by Vicinal Sulfur-containingTetrasubstituted Stereocenters.Org. Chem. Front.,2018,5, 3226-3230. (IF = 5.45) Yuyu Cheng, Zhiqiang Fang,Wenjun Li*, Pengfei Li*. Phosphine-mediated Enantioselective [4 + 1] Annulations betweenOrtho-quinone methides and Morita-Baylis-Hillman Carbonates.Org. Chem. Front.,2018,5, 2728-2733. (IF = 5.45) Lili Zhang, Huijun Yuan, Wei Lin, Yuyu Cheng, Pengfei Li*,Wenjun Li*. Catalyst-Controlled Diastereodivergent Construction of Vicinal Sulfur-Functionalized Quaternary and Tertiary Stereocenters.Org. Lett.,2018,20, 4970-4974. (IF = 6.49) Qiuhong Huang, Lili Zhang, Yuyu Cheng, Pengfei Li*,Wenjun Li*. Enantioselective Construction of Vicinal Sulfur-containing Tetrasubstituted Stereocenters via Organocatalyzed Mannich-Type Addition of Rhodanines to Isatin Imines.Adv. Synth. Catal.2018,360, 3266-3270. (IF = 5.12) Wenjun Li*, Xianhong. Xu, Pengfei. Zhang, Pengfei Li*. Recent Advances in Catalytic Enantioselective Reactions ofpara-Quinone Methides.Chem. Asian J.2018,13, 2350-2359. (IF = 3.69) Wenjun Li*, Huijun Yuan, Zhantao Liu, Zhongyin Zhang, Yuyu Cheng, Pengfei Li*. NHC-catalyzed Enantioselective [4 + 3] Cycloaddition ofortho-Hydroxyphenyl Substitutedpara-Quinone Methides with Isatin-Derived Enals.Adv. Synth. Catal.2018,360, 2460-2464. (高被引论文,IF = 5.12) Wenjun Li*, Xianhong Xu, Yang Liu, Hua Gao, Yuyu Cheng, Pengfei Li*. Enantioselective Organocatalytic 1,6-Addition of Azlactones topara-Quinone Methides: An Access to α,α-Disubstituted and β,β-Diaryl-α-amino acid Esters.Org. Lett.,2018,20, 1142-1145. (高被引论文,IF = 6.49) Xinye Shang, Kun Liu, Zhongyin Zhang, Xianhong Xu, Pengfei Li*,Wenjun Li*. Direct Access to Spirobiisoxazoline via the Double 1,3-Dipolar Cycloaddition of Nitrile Oxide with Allenoate.Org. Biomol. Chem.,2018,16, 895-898. (IF = 3.42)