个人简介
教育经历
2000.9-2003.12 厦门大学|动物学专业|博士
1994.9-1997.6 厦门大学|微生物学专业|硕士
1990.9-1994.6 湖南科技大学|生物学专业|学士
工作经历
2005.8-至今 集美大学|海洋食品与生物工程学院|教授（2010年）
2018.7-2018.9 香港中文大学|生命科学学院|高级访问学者-荣誉副研究员
1997.7-2005.7 厦门出入境检验检疫局|技术中心|高级工程师（2004年）
2014.5-2014.7 英国诺丁汉大学|食品营养学系|高级访问学者
2011.1-2011.3 台湾大学|生化科技学系|高级访问学者
2008.9-2009.3 美国农业部|南方农业研究中心食品化学研究室|访问学者
2004.6-2006.5 汕头大学|基础医学博士后科研流动站|博士后
近期论文
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Cloning, expression, and epitope identification of myosin light chain 1: An allergen in mud crab. J. Agric. Food Chem., 2019, 67(37): 10458~10469 （通讯作者）
Crystal structure analysis and conformational epitope mutation of triosephosphate isomerase, a mud crab allergen. J. Agric. Food Chem., 2019, 67(46): 12918~12926 （通讯作者）
Reducing allergenicity to arginine kinase from mud crab using site-directed mutagenesis and peptide aptamers. J. Agric. Food Chem., 2019, 67(17): 4958~4966 （通讯作者）
Effects of thermal processing on digestion stability and immunoreactivity of the Litopenaeus vannamei matrix. Food & Func., 2019, 10(9): 5374~5385 （通讯作者）
A comprehensive analysis of the allergenicity and IgE epitopes of myosinogen allergens in Scylla paramamosain. Clin. Exp. Allergy, 2019, 49(1): 108~119 （通讯作者）
Reducing allergenicity to arginine kinase from mud crab using site-directed mutagenesis and peptide aptamers. J Agric Food Chem., 2019, 67(17): 4958~4966 （通讯作者）
Cloning, expression and comparison of the properties of Scy p 9, a Scylla paramamosain allergen. Food & Func., 2020, 11(4): 3006~3019 （通讯作者）
Identification and cross-reactivity analysis of sarcoplasmic -calcium-binding protein: A novel allergen in Crassostrea angulata. J. Agric. Food Chem., 2020, 68(18): 5221~5231 （通讯作者）
Site-directed mutations of calcium-binding sites contribute to reducing the immunoreactivity of the EF-hand sarcoplasmic calcium-binding protein in Scylla paramamosain. J. Agric. Food Chem., 2020, 68(24): 428~436 （通讯作者）
Combination processing method reduced IgE-binding activity of Litopenaeus vannamei by modifying lysine, arginine, and cysteine on multiple allergen epitopes. J. Agric. Food Chem., 2021, 69(16): 4865~4873 （通讯作者）
Effects of thermal processing on the allergenicity, structure, and critical epitope amino acids of crab tropomyosin. Food & Func., 2021, 12(5): 2032~2043 （通讯作者）
Identification and characterization of Crassostrea angulata arginine kinase, a novel allergen that causes cross-reactivity among shellfish. Food & Func., 2021, 12(20): 9866~9879 （通讯作者）
IgE epitope analysis of sarcoplasmic-calcium binding protein, a heat-resistant allergen in Crassostrea angulata. Food & Func., 2021, 12(18): 8570~8582 （通讯作者）
Linear epitopes play an important role in the Immunoglobulin G (IgG)/Immunoglobulin E (IgE) binding capacity of Scy p 4. J. Agric. Food Chem., 2021, 69(43): 12870~12879 （通讯作者）
Mapping and IgE-binding capacity analysis of heat/digested stable epitopes of mud crab allergens. Food Chem., 2021, 344: 128735~128735 （通讯作者）
Two allergens from Scylla paramamosain share common epitopes showed different allergenic potential in Balb/c mice. Food Chem., 2021, 371: 131132 （通讯作者）
Analysis of immunoreactivity of α/α2-tropomyosin from Haliotis discus hannai, based on IgE epitopes and structural characteristics. J. Agric. Food Chem., 2021, 69(50): 15403~15413 （通讯作者）
Site-directed mutations of calcium-binding sites contribute to reducing the immunoreactivity of the EF-hand sarcoplasmic calcium-binding protein in Scylla paramamosain. J Agric Food Chem., 2021, 69(1): 428~436 （通讯作者）
Identification of linear epitopes and the major role in the Immunoglobulin E-binding capacity of tropomyosin from Alectryonella plicatula. Food Funct., 2022, 13(17): 9078~9090 （通讯作者）
Characterization, epitope identification, and cross-reactivity analysis of tropomyosin: An important allergen of Crassostrea angulata. J. Agric. Food Chem., 2022, 70(29): 9201~9213 （通讯作者）
IgE epitope analysis for Scy p 1 and Scy p 3, the heat-stable myofibrillar allergens in mud crab. J. Agric. Food Chem., 2022, 70(38): 12189~12202 （通讯作者）
Two hypo-allergenic derivatives lacking the dominant linear epitope of Scy p 1 and Scy p 3. Food Chem., 2022, 373: 131588 （通讯作者）
IgE epitope analysis and hypo-immunoreactivity derivative of arginine kinase in mantis shrimp (Oratosquilla oratoria). J Agric Food Chem., 2023, 71(24):9508~9518 （通讯作者）
Comparative analysis of tropomyosin allergenicity for three different species of molluscs Insights into the role of amino acids composition in IgE epitopes. Food & Func., 2024, Accepted （通讯作者）
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