个人简介
男，1988年生。理学博士，副教授，硕士生导师。2010年毕业于南开大学信息技术科学学院信息安全专业，获得工学学士学位。2015年毕业于南开大学生命科学学院，获得理学博士学位师从饶子和院士。任职以来，承担及参与多项国家自然科学基金项目，目前从事金属蛋白结构与功能、蛋白结构设计与改造的研究工作。相关研究成果发表在Proc Natl Acad Sci, J Am Chem Soc, Angew Chem Int Ed, ACS Nano, Chinese Chemical Letters, Chem Commun, Inorganic Chemistry，Journal of Virology等国际权威期刊发表学术论文30余篇。
研究领域
金属蛋白结构测定与功能研究
金属蛋白结构设计与改造
近期论文
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Wang Wenming, Xi Hongfang, Fu Dan, Ma Danyang, Gong Wenjun, Zhao Yaqin, Li Xiaomei, Wu Lijie, Guo Yu, Zhao Guanghua, Hongfei Wang. The growth process of Fe-O nanoclusters with different sizes biosynthesized by protein nanocage. Journal of the American Chemical Society, 2024.
Wang wenming, Wang Yuan, Xi Hongfang, Song Zidan, Zhang Wenlong, Xie Leilei, Ma Danyang, Qin Nan, Wang Hongfei. Extension Peptide of Plant Ferritin from Setaria italica Presents a Novel Fold. J. Agric. Food Chem, 2023, 71, 934−943.
Bai Hehe, Gong Wenjun, Pang Yating, Shi Chaoyang, Zhang Zhigang, Guo Lili, Li Yafeng, Wenming Wang, Wang Hongfei. Synthesis, cytotoxicity, and biomacromolecule binding: Three isomers of nitrosylruthenium complexes with bidentate bioactive molecules as co-ligands. International Journal of Biological Macromolecules, 2023, 243:125009. (共同通讯作者)
Wang Wenming, Liu xiaojia, Wang Yajie, Wang Yuan, Fu Dan, Xi Hongfang, Zhao Yi, Wang Hongfei. Distinct structural characteristics define a new subfamily of Mycoplasma ferritin. Chinese Chemical Letters, 2022, 33: 4952–4955.
Wang Deping, Wang Meiyue, Li Yongmei, Wen Shu, Cui Wen, Jiang Fangying, Zhou Xin, Wang Wenming, Cao Jimin. Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design. Cell & Bioscience (2022) 12:44. （共同通讯作者）
Wang Wenming, Zhang Yao, Zhao Guanghua, Wang Hongfei. Ferritin with Atypical Ferroxidase Centers Takes B-Channels as the Pathway for Fe2+ Uptake from Mycoplasma. Inorganic Chemistry, 2021, 60, 10, 7207-7216.
Cui Xiaodong, Wang Ke, Wang Tingfen, Li Jiao, Li Chen, Wang Wenming, Wang Hongfei, Wang Zhuanhua. Crystal Structure Analysis of Cationic Peroxidase from Proso Millet and Identific ation of Its Phosphatase Active Sites, Journal of Agricultural and Food Chemistry, 2021, 69(22): 6251-6259. （共同通讯作者）
Wang Wenming, Wang Lele, Li Guobang, Zhao Guanghua, Zhao Xuan, Wang Hongfei. AB loop engineered ferritin nanocages for drug loading under benign experimental conditions., Chemical Communications, 2019, 55(82):12344-12347.
Wang Wenming, Wang Lele, Chen Hai, Zang Jiachen, Zhao Xuan, Zhao Guanghua, Wang Hongfei. Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings, Journal of the American Chemical Society, 2018, 140:14078-14081.
Zhou Kai, Zang Jiachen, Chen Hai, Wang Wenming, Wang Hongfei, Zhao Guanghua. On-Axis Alignment of Protein Nanocage Assemblies from 2D to 3D through the Aromatic Stacking Interactions of Amino Acid Residues. ACS Nano, 2018，12, 11323-11332.
Zhang Shengli, Zang Jiachen, Wang Wenming, Chen Hai, Zhang Xiaorong, Wang Fudi, Wang Hongfei, Zhao Guanghua. Conversion of the Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues. Angewandte Chemie International Edition, 2016, 55(52): 16064-16070.
Wang Wenming; Liu Xiang; et al. Structural and Functional Diversity of Nairovirus-Encoded Nucleoproteins. Journal Of Virology, 2015, 89(23): 11740-11749.
Guo Yu, Wang Wenming, Sun Yuna, et al. Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation. Journal Of Virology, 2016, 90(2): 1048-1061. (共同第一作者)
Guo Yu, Wang Wenming, Ji Wei, et al. Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses. Proc Natl Acad Sci USA, 2012, 109(13): 5046-5051. (共同第一作者)
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