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炎症及免疫反应:主攻朊蛋白对各种细胞炎症及免疫反应的调节作用,以及最终对相关疾病发生发展的影响,比如肿瘤、自身免疫性疾病 肿瘤的免疫治疗:通过改造特定基因的表达来改善免疫细胞的抗肿瘤作用 神经发育相关疾病:研究某些神经发育相关临床综合征的发病机制

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Tang Z, Ma J, Zhang W, Gong C, He J, Wang Y, Yu G, Yuan C, Wang X, Sun Y, Ma J, Liu F*, Zhao Y*. The Role of Prion Protein Expression in Predicting Gastric Cancer Prognosis. J Cancer. 2016 May 20;7(8):984-90. He J, Zhu J, Gong C, Qi J, Xiao H, Jiang B*, Zhao Y*. Label-Free Direct Detection of miRNAs with Poly-Silicon Nanowire Biosensors. PLoS One. 2015 Dec 28;10(12):e0145160. Gong C, Wei D, Wang Y, Ma J, Yuan C, Zhang W, Yu G, Zhao Y*. A Meta-Analysis of C-Reactive Protein in Patients With Alzheimer's Disease. Am J Alzheimers Dis Other Demen. 2016 May;31(3):194-200. He X*, Yin W, Ding Y, Cui SJ, Luan J, Zhao P, Yue X, Yu C, Laing X*, Zhao Y*. Higher Serum Angiotensinogen Is an Indicator of IgA Vasculitis with Nephritis Revealed by Comparative Proteomes Analysis. PLoS One. 2015 Jun 22;10(6):e0130536. Yu G, Liu H, Zhou W, Zhu X, Yu C, Wang N, Zhang Y, Ma J, Zhao Y, Xu Y, Liao L, Ji H, Yuan C, Ma J*. In vivo protein targets for increased quinoprotein adduct formation in aged substantia nigra. Exp Neurol. 2015 Sep;271:13-24. He J, Zhang F, Wu Y, Zhang W, Zhu X, He X, Zhao Y, Zhang W, Zhao Y*. Prognostic role of microRNA-155 in various carcinomas: results from a meta-analysis.Dis Markers. 34(6):379-86, 2013. Zhu X, Zhang F, Zhang W, He J, Zhao Y*, Chen X*. Prognostic role of epidermal growth factor receptor in head and neck cancer: a meta-analysis. J Surg Oncol. 108(6):387-97, 2013. Zhao D, Zhang F, Zhang W, He J, Zhao Y*, Sun J*. Prognostic role of hormone receptors in ovarian cancer: a systematic review and meta-analysis. Int J Gynecol Cancer. 23(1):25-33, 2013. Zhang W, He J, Zhang F, Huang C, Wu Y, Han Y, Zhang W, Zhao Y*. Prognostic role of C-reactive protein and interleukin-6 in dialysis patients: a systematic review and meta-analysis. J Nephrol. 26(2):243-53, 2013. He X, Zhao Y, Li Y, Kang S, Ding Y, Luan J, Zhao P, Liu N, Yin W. Serum amyloid A levels associated with gastrointestinal manifestations in Henoch-Sch?nlein purpura. Inflammation. 35(4):1251-5012, 2012.(共同第一作者) Han Y, Mao F, Wu Y, Fu X, Zhu X, Zhou S, Zhang W, Sun Q, Zhao Y*. Prognostic role of C-reactive protein in breast cancer: a systematic review and meta-analysis. Int J Biol Markers. 2011 Dec 2:0. doi: 10.5301/JBM.2011.8872. Fu X, Han Y, Wu Y, Zhu X, Lu X, Mao F, Wang X, He X, Zhao Y, Zhao Y*. Prognostic role of microRNA-21 in various carcinomas: a systematic review and Meta-analysis. Eur J Clin Invest. 41(11):1245-53,2011. Wu Y, Zhao Y*. Editorial Comment to Erythrocyte sedimentation rate kinetics as a marker of treatment response and predictor of prognosis in Chinese metastatic renal cell carcinoma patients treated with sorafenib. Int J Urol. 18(6):430-1,2011. Li D, Zhao Y, Liu C, Chen X, Qi Y, Jiang Y, Zou C, Zhang X, Liu S, Wang X, Zhao D, Sun Q, Zeng Z, Dress A, Lin MC, Kung HF, Rui H, Liu LZ, Mao F, Jiang BH, Lai L*. Analysis of miR-195 and miR-497 expression, regulation and role in breast cancer. Clin Cancer Res. 17(7):1722-30,2011.(共同第一作者) Wu Y, Fu X, Zhu X, He X, Zou C, Han Y, Xu M, Huang C, Lu X, Zhao Y*. Prognostic role of systemic inflammatory response in renal cell carcinoma: a systematic review and meta-analysis. J Cancer Res Clin Oncol. 137(5):887-96, 2011. Li H, Zhao Y, Zhou S, Heng CK. Serum amyloid A activates peroxisome proliferator-activated receptor γ through extracellularly regulated kinase 1/2 and COX-2 expression in hepatocytes. Biochemistry. 2010 Nov 9;49(44):9508-17. Zhao Y, Chan MY, Zhou S, Heng CK. Effects of atherogenic diet and atorvastatin treatment on gene expression profiles in the C57BL/6J mouse liver. Gene Expr. 2008;14(3):149-58. Zhao Y, Zhou S, Heng CK. Celecoxib inhibits serum amyloid a-induced matrix metalloproteinase-10 expression in human endothelial cells. J Vasc Res. 2009;46(1):64-72 Chan MY, Zhao Y, Heng CK. Sequential responses to high-fat and high-calorie feeding in an obese mouse model. Obesity (Silver Spring). 2008 May;16(5):972-8. Zhao Y, Zhou S, Heng CK. Impact of serum amyloid A on tissue factor and tissue factor pathway inhibitor expression and activity in endothelial cells. Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1645-50. 石学桂,赵宇岚*,王秋杰。血清淀粉样蛋白A通过NFκB途径诱导人脐静脉内皮细胞E-选择素的表达。《南京医科大学学报(自然科学版)》2010,(10):1393-1396。

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