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个人简介

余家会,男,1971年10月生,研究员,博士生导师;1990-2000年于武汉大学获理学学士,硕士及博士学位;2000-2003年于中科院上海有机化学研究所完成博士后研究;2003年受聘为中科院上海应用物理研究所副研究员、硕士生导师、博士生指导小组成员;2005年起任华东师范大学任副研究员、研究员、博士生导师;2007-2008选聘为“中韩青年交流学者”于首尔国立大学农学与生命科学学院访问。该教授一直从事抗肿瘤药物递释体系、分子影像对比剂、组织工程材料研究。主持参与科技部863,973计划项目、国家自然科学基金、教育部留学回国人员基金、上海市纳米专项项目、上海市国际合作项目等多项。发表研究论文100多篇,授权发明专利20多项,参与5部中、英文专著章节撰写。 教育经历 1997/09 - 2000/06,武汉大学,博士 1994/09 - 1997/06,武汉大学,硕士 1990/09 - 1994/06,武汉大学,学士 工作经历 研究单位任职 2012/12 - 至今,华东师范大学,化学与分子工程学院,研究员 2005/04 - 2012/12,华东师范大学,科学与技术跨学科高等研究院,副研究员 2003/09 - 2005/04,中科院上海应用物理研究所,副研究员 研究单位博士后 2007/03-2008/03,首尔国立大学,农学与生命科学学院,“中韩青年交流学者” 博士后 2000/07 - 2003/08,中科院上海有机化学研究所,博士后 地方挂职 2017/09-2018/08,江苏如东高新区副主任 2016/09-2017/08, 江苏宜兴高塍镇副镇长,宜兴市环保局副局长

研究领域

抗肿瘤药物递释系统、分子影像对比剂、组织工程材料 专题1:分子药物递释体系(ADC, Pseudo-ADC, AOC, PDC, SMDC) 专题2:纳米药物及高分子药物 专题3:组织工程材料 专题4:磁共振分子影像诊断对比剂

近期论文

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Xing Jiang, Lingyi Zhu, Qingyu Wei, Wei Lu, Jiahui Yu*, Shulei Zhu*, Enhancing SN38 prodrug delivery using a self-immolative linker and endogenous albumin transport, Journal of Controlled Release, 369,622-629, 2024. Danqing Zhou, Jiahui Yu*, Qiuhua Zhao,* and Lidong Zhang*, In-situ permeation of liquid cationic polymer into solid anionic polymer film enabling self-adaptive adhesion of hydrogel biosensors, Materials Horizon, 10, 3622–3630, 2023. Yang He, Yanyun Xu, Yushu Huang, Hao Quang, Xiaoyan Xia, Hongbo Zhao, Yi Xiao, Wei Lu, Jiahui Yu*, Redox sensitive nano-capsules self-assembled from hyaluronic acid-hydroxychloroquine conjugates for cd44-targeted delivery of hydroxychloroquine to combat breast cancer metastasis in vitro and in vivo, Colloids and Surfaces B: Biointerfaces, 210, 112249, 2022. Mengda Xu, Yan Miao, Xiaxin Qiu,Xiaodong Song, Qiuhua Zhao, Jiahui Yu,* and Lidong Zhang*, Swelling-induced information camouflage and optical decryption on a transparent recoverable hydrogel surface, ACS Applied Materials & Interfaces, 14, 2, 3591–3600, 2022. Mengda Xu, Yan Miao,Jiahui Yu*, Lidong Zhang*, Physiologically-regulated adhesion of hydrogels for wound dressing, Advanced Materials Interfaces. 2101131, 8(20), 2021. Na Li, Yiwei Wang, Yuqi Guo, Zhenyu Ji, Zhuangli Zhang, Jiahui Yu*, Lianzhong Zhang*, Surface modified cellulose nanocrystalline hybrids actualizing efficient and precise delivery of doxorubicin into nucleus with: In vitro and in vivo evaluation, Journal of Applied Polymer Science, 138,e51536,2021. Hao Quan, Li Fan (first coauthor), Yushu Huang, Xiaoyan Xia, Yang He, Shiyuan Liu*, Jiahui Yu*, Hyaluronic acid-decorated carborane-TAT conjugation nanomicelles: A potential boron agent with enhanced selectivity of tumor cellular uptake, Colloids and Surfaces B: Biointerfaces, 204, 111826,2021. Yushu Huang, Yang He, Xiaoyan Xia, Hao Quan,Jiahui Yu*, Phenylboronic acid-functionalized co-delivery micelles with synergistic effect and down-regulation of HIF-1alpha to overcome multidrug resistance, Journal of Drug Delivery Science and Technology, 62, 102346, 2021. Yan Miao, Mengda Xu, Jiahui Yu*, Lidong Zhang*, Conductive cold-resistant and elastic hydrogel: A potential bionic skin for human-machine interaction control over artificial limbs, Sensors & Actuators: B. Chemical, 327, 128916, 2021. Yushu Huang, Wanli Zhang, Yanyun Xu, Shulei Zhu, Yanqian Wu, Tiandong Chen, Yi Xiao, Wei Lu, Xiongwen Zhang, Jiahui Yu*, Dynamic core crosslinked camptothecin prodrug micelles with reduction sensitivity and boronic acid-mediated enhanced endocytosis: an intelligent tumor-targeted delivery nanoplatform, International Journal of Pharmaceutics, 580, 119250-119261, 2020. Yuliu Zhang, Yi Xiao, Yushu Huang, Yang He, Yanyun Xu, Wei Lu, Jiahui Yu*, Poly(ethylene glycol) shell-sheddable TAT-modified core cross-linked nano-micelles: TAT-enhanced cellular uptake and lysosomal pH-triggered doxorubicin release, Colloids and Surfaces B: Biointerfaces, 188, 110772-110780, 2020. Yanyun Xu, Yushu Huang, Wei Lu, Shiyuan Liu, Yi Xiao*, Jiahui Yu*, 4-Carboxyphenylboronic acid-decorated, redox-sensitive rod-shaped nano-micelles fabricated through co-assembling strategy for active targeting and synergistic co-delivery of camptothecin and gemcitabine, European Journal of Pharmaceutics and Biopharmaceutics, 144, 193-206,2019. Yushu Huang, Yanyun Xu, Yanqian Wu, Tiandong Chen, Wei Lu, Jiahui Yu*, Bioinspired nanoplatform for enhanced delivery efficiency of doxorubicin into nucleus with fast endocytosis, lysosomal pH-triggered drug release, and reduced efflux, Colloids and Surfaces B: Biointerfaces, 183, 110413, 2019. Yanqian Wu, Yi Xiao (first coauthor), Yushu Huang, Yanyun Xu, Donglei You, Wei Lu, Jiahui Yu*,Rod-shaped micelles based on PHF-g-(PCL-PEG) with pH-triggered doxorubicin release and enhanced cellular uptake, Biomacromolecules, 20, 1167–1177, 2019. Na Li, Han Zhang, Yi Xiao, Yushu Huang, Mengda Xu, Donglei You, Wei Lu, Jiahui Yu*, Fabrication of cellulose nanocrystals-based folate targeted nanomedicine via layer-by-layer assembly with lysosomal pH-controlled drug release into nucleus, Biomacromolecules, 20, 937–948, 2019. Yanyun Xu, Yushu Huang, Xiongwen Zhang, Wei Lu, Jiahui Yu*, Shiyuan Liu, Carrier-free Janus nano-prodrug based on camptothecin and gemcitabine: Reduction-triggered drug release and synergistic in vitro antiproliferative effect in multiple cancer cells, International Journal of Pharmaceutics, 550, 45–56, 2018. Na Li, Wei Lu, Jiahui Yu*, Yi Xiao, Shiyuan Liu, Lin Gan, Jin Huang*, Rod-like cellulose nanocrystal/cis-aconityl-doxorubicin prodrug: A fluorescence-visible drug delivery system with enhanced cellular uptake and intracellular drug controlled release, Materials Science & Engineering C, 91, 179-189, 2018. Li Cao, Yi Xiao (first coauthor), Wei Lu, Shiyuan Liu, Lin Gan, Jiahui Yu* and Jin Huang, Nanomicelle drug with acid-triggered doxorubicin release and enhanced cellular uptake ability based on mPEG-graft-poly(N-(2-aminoethyl)-Laspartamide)-hexahydrophthalic acid copolymers, Journal of Biomaterials Applications, 32, 826–838, 2018. Tiandong Chen, Yi Xiao (first coauthor), Wei Lu, Shiyuan Liu, Lin Gan, Jiahui Yu*, Jin Huang, Facile preparation of core cross-linked nanomicelles based on graft copolymers with pH responsivity and reduction sensitivity for doxorubicin delivery, Colloids and Surfaces B: Biointerfaces, 161, 606–613, 2018. Ya Gao, Yi Xiao (first coauthor), Shiyuan Liu and Jiahui Yu*,Camptothecin prodrug nanomicelle based on a boronate ester-linked diblock copolymer as the carrier of doxorubicin with enhanced cellular uptake, Journal of Biomaterials Science: Polymer Edition, 29, 160-180, 2018. Yushu Huang, Ya Gao, Tiandong Chen, Yanyun Xu, Wei Lu, Jiahui Yu*, Yi Xiao**, and Shiyuan Liu, reduction-triggered release of CPT from acid-degradable polymeric prodrug micelles bearing boronate ester bonds with enhanced cellular uptake, ACS Biomater. Sci. Eng., 3, 3364-3375, 2017. Yanyun Xu, Xin Zhong, Xiongwen Zhang, Wei Lv, Jiahui Yu*, Yi Xiao**, Shiyuan Liu, Jin Huang, Preparation of intravenous injection nanoformulation via co-assemble between cholesterylated gemcitabine and cholesterylated mPEG: Enhanced cellular uptake and intracellular drug controlled release, Journal of Microencapsulation, 34, 185-194, 2017. Yan Xu, Yuanyuan Lu, Lei Wang, Wei Lu, Jin Huang, Ben Muir, Jiahui Yu* Nanomicelles based on a boronate ester-linked diblock copolymer as the carrier of doxorubicin with enhanced cellular uptake,Colloids and Surfaces B: Biointerfaces, 141, 318-326, 2016. Jiahui Yu*, Haijing Meng, Fang Du, Jin Huang, WeiLu, Yu Luo, Enhanced solubility, stability, and antitumor activity of the VESylated gemcitabine prodrug by co-assembly with TPGS, Journal of Controlled Release, 213, e48, 2015. Yanyun Xu, Haijing Meng, Fang Du, Wei Lu, Shiyuan Liu, Jin Huang, Jiahui Yu*, Preparation of intravenous injection nanoformulation of VESylated gemcitabine by co-assembly with TPGS and its anti-tumor activity in pancreatic tumor-bearing mice, International Journal of Pharmaceutics, 495, 792-797, 2015. Haitao Huang, Jianqi Geng, Jafar Golzarian, Jin Huang*, Jiahui Yu**,Fabrication of doxorubicin-loaded ellipsoid micelle based on diblock copolymer with a linkage of enzyme-cleavable peptide, Colloids and Surfaces B: Biointerfaces, 133, 362-369, 2015. Haitao Huang, Tao Yue, Yanyun Xu, Ke Xu, Haibo Xu, Shiyuan Liu, Jiahui Yu*, Jin Huang**, PEGylation of MnO nanoparticles via catechol–Mn chelation to improving T1-weighted magnetic resonance imaging application, Journal of Applied Polymer Science, 132, 42360, 2015. Haitao Huang, Tao Yue, Ke Xu, Jafar Golzarian, Jiahui Yu*, Jin Huang**, Fabrication and evaluation of tumor-targeted positive MRI contrast agent based on ultrasmall MnO nanoparticles, Colloids and Surfaces B: Biointerfaces, 131, 148-154, 2015. Yanfen Fang, Fang Du, Haijing Meng, Jin Huang, Xiongwen Zhang, Wei Lu, Jiahui Yu*, Enhanced cellular uptake and intracellular drug controlled release of VESylated gemcitabine prodrug nanocapsules, Colloids and Surfaces B: Biointerfaces, 128, 357-362, 2015. Yanyun Xu, Jianqi Geng, Ping An, Yan Xu, Jin Huang, Wei Lu, Shiyuan Liu, Jiahui Yu*, Cathepsin B-sensitive cholesteryl hemisuccinate-gemcitabine prodrug nanoparticles: Enhanced cellular uptake and intracellular drug controlled release, RSC Advance, 5, 6985-6992, 2015. Haijing Meng, Ke Xu, Yanyun Xu, Ping Luo, Fang Du, Jin Huang, Wei Lu, Jiahui Yu*, Shiyuan Liu, Ben Muir, Nanocapsules based on mPEGylated artesunate and its cytotoxicity, Colloids and Surfaces B: Biointerfaces, 115, 164-169, 2014. Fang Du, Haijing Meng, Ke Xu, Yanyun Xu, Ping Luo, Yu Luo, Wei Lu, Jin Huang, Shiyuan Liu, Jiahui Yu*, CPT loaded nanoparticles based on beta-cyclodextrin-grafted poly(ethylene glycol)/poly (L-glutamic acid) diblock copolymer and their inclusion complexes with CPT, Colloids and Surfaces B: Biointerfaces, 113, 230-236, 2014. Ping Luo, Yu Luo, Jin Huang, Wei Lu, Dajun Luo, Jiahui Yu*, Shiyuan Liu**, Incorporation of camptothecin into reduction-degradable supramolecular micelles for enhancing its stability, Colloids and Surfaces B: Biointerfaces, 109, 167-175, 2013. Jiahui Yu*, Xiangyang Li, Yu Luo, Wei Lu, Jin Huang **, Shiyuan Liu***, Poly(ethylene glycol) shell-sheddable magnetic nanomicelle as the carrier of doxorubicin with enhanced cellular uptake, Colloids and Surfaces B: Biointerfaces, 107, 213-219, 2013. Qinge Wu, Fang Du, Yu Luo, Wei Lu, Jin Huang, Jiahui Yu*, Shiyuan Liu**, Poly(ethylene glycol) shell-sheddable nanomicelle prodrug of camptothecin with enhanced cellular uptake, Colloids and Surfaces B: Biointerfaces, 105, 294-302, 2013. Dawei Yong, Yu Luo, Fang Du, Jin Huang, Wei Lu, Zhaoyun Dai, Jiahui Yu*, Shiyuan Liu**, CDDP supramolecular micelles fabricated from adamantine terminated mPEG and b-cyclodextrin based seven-armed poly (L-glutamic acid)/CDDP complexes, Colloids and Surfaces B: Biointerfaces, 105, 31-36, 2013. Qian Guo, Ping Luo, Yu Luo, Fang Du, Wei Lu, Shiyuan Liu, Jin Huang, Jiahui Yu*, Fabrication of biodegradable micelles with sheddable poly(ethylene glycol) shells as the carrier of 7-ethyl-10-hydroxy-camptothecin, Colloids and Surfaces B: Biointerfaces, 100, 138-145, 2012. Xuzhu Zhang, Fang Du, Jin Huang, Wei Lu, Shiyuan Liu, Jiahui Yu*, Fabrication of biodegradable micelles with reduction-triggered release of 6-mercaptopurine profile based on disulfide-linked graft copolymer conjugate, Colloids and Surfaces B: Biointerfaces, 100, 155-162, 2012. Liang Ding, Guangda Yang, Meiran Xie*, Danyi Gao, Jiahui Yu* Yiqun Zhang, More insight into tandem ROMP and ADMET polymerization for yielding reactive long-chain highly branched polymers and their transformation to functional polymer nanoparticles, Polymer, 53, 333-341, 2012. Jiahui Yu, Honglei Fan, Jin Huang*, Jinghua Chen, Fabrication and evaluation of reduction-sensitive supramolecular hydrogel based on cyclodextrin/polymer inclusion for injectable drug-carrier application, Soft matter, 7, 7386 – 7394, 2011. Yake Xue, Xiaoxing Tang, Jin Huang, Xuzhu Zhang, Jiahui Yu*, Yazhuo Zhang*, Songbai Gui, Anti-tumor efficacy of polymer–platinum (II) complex micelles fabricated from folate conjugated PEG-graft-α, β-poly [(N-amino acidyl)-aspartamide] and cis-dichlorodiammine platinum (II) in tumor-bearing mice, Colloids and Surfaces B: Biointerfaces, 85, 280-288, 2011. Yanyun Liu, Yun Liu, Zhongshi Liang, Xiangyang Li, Shunying Liu*, JiahuiYu*, Enhanced sensitivity and selectivity of chemosensor for malonate by anchoring on gold nanoparticles,Chinese Journal of Chemistry, 29, 531-538, 2011. Weilu Zhang, Na Li, Jin Huang, Shufang Luo, Mingxia Fan, Shiyuan Liu, Ben Muir, Jiahui Yu*, Gadolinium-conjugated folate-poly(ethylene glycol)-polyamidoamine dendrimer-carboxyl nanoparticles as potential tumor-targeted, circulation-prolonged macromolecular magnetic resonance imaging contrast agents (II), Journal of Applied Polymer Science, 121, 3175-3184, 2011. Weilu Zhang, Dawei Yong, Jin Huang, Jiahui Yu*, Shiyuan Liu and Mingxia Fan*, Fabrication of polymer-gadolinium (III) complex nanomicelle from poly(ethylene glycol)-polysuccinimide conjugate and diethylenetriaminetetraacetic acid-gadolinium as magnetic resonance imaging contrast agents, Journal of Applied Polymer Science, 120, 2596-2605, 2011. Honglin Chen, Jin Huang, Jiahui Yu*, Shiyuan Liu*, Ping Gu, Electrospun chitosan-graft-poly (ε-caprolactone)/poly (ε-caprolactone) cationic nanofibrous mats as potential scaffolds for skin tissue engineering, International Journal of Biological Macromolecules, 48, 13-19, 2011. Jingwei Liu, Yang Liao, Xiaohua He, Jiahui Yu*, Liang Ding, Meiran Xie*, Facile one-pot approach for preparing functionalized polymeric nanoparticle via ring-opening metathesis polymerization, Macromolecular Chemistry and Physics, 212, 55-63, 2011. Liya Zhang, Chunmei Song, Jiahui Yu*, Dan Yang, Meiran Xie*, One-pot synthesis of polymeric nanoparticle by ring-opening metathesis polymerization,Journal of Polymer Science Part A-Polymer Chemistry, 48, 5231-5238, 2010. Dan Yang? Wei Huang? Jiahui Yu*? Jisen Jiang? Liya Zhang? Meiran Xie*? A novel shape memory polynorbornene functionalized with poly(ε-caprolactone) side chain and cyano group through ring-opening metathesis polymerization? Polymer? 51? 5100-5106? 2010. Honglei Fan? Jin Huang*? Yaping Li? Jiahui Yu*? Jinghua Chen? Fabrication of reduction-degradable micelle based on disulfide-linked graft copolymer-camptothecin conjugate for enhancing solubility and stability of camptothecin? Polymer? 51, 5107-5114, 2010. Jin Huang? Feng Gao? Xiaoxin Tang? Jiahui Yu*? Daxin Wang? Shiyuan Liu*? Yaping Li? Liver-targeting doxorubicin-conjugated polymeric prodrug with pH-triggered drug release profile? Polymer International? 59? 1390-1396? 2010. Weilu Zhang? Jin Huang? Naiqian Fan? Jiahui Yu*? Yongbiao Liu? Shiyuan Liu*? Daxin Wang? Yaping Li? Nanomicelle with long-term circulation and enhanced stability of camptothecin based on mPEGylated α?β-Poly (L-aspartic acid)-camptothecin conjugate? Colloids and Surfaces B: Biointerfaces, 81, 297-303, 2010. Xiaolan Zhang? Zhongying Hui? Daxin Wang? Haitao Huang? Jin Huang*? Hong Yuan? Jiahui Yu*? Alginate microspheres filled with carbon nanotube as a drug carrier? International Journal of Biological Macromolecules? 47? 389-395? 2010. Weilu Zhang? Na Li? Jin Huang? Jiahui Yu*? Daxin Wang? Yaping Li? Shiyuan Liu*? Gadolinium-conjugated FA-PEG-PAMAM-COOH nanoparticles as potential tumor-targeted circulation-prolonged macromolecular MRI contrast agents? Journal of Applied Polymer Science? 118? 1805-1814? 2010. Kongrong Duan? Xiaolan Zhang? Xiaoxing Tang? Jiahui Yu*? Shiyuan Liu? Daxin Wang? Yaping Li? Jin Huang*? Fabrication of cationic nanomicelle from chitosan-graft-polycaprolactone as the carrier of 7-ethyl-10-hydroxy-camptothecin? Colloids and Surfaces B: Biointerfaces? 76? 475-482? 2010. Kongrong Duan? Honglin Chen? Jin Huang? Jiahui Yu*? Shiyuan Liu? Daxin Wang? Yaping Li? One-step synthesis of amino-reserved chitosan-graft-polycaprolactone as a promising substance of biomaterial? Carbohydrate Polymers? 80? 499-504? 2010. Naiqian Fan? Kongrong Duan? Chengyun Wang? Shunying Liu? Shufang Luo? Jiahui Yu*? Jin Huang? Yaping Li? Daxin Wang? Fabrication of nanomicelle with enhanced solubility and stability of camptothecin based on α? β-poly [(n-carboxybutyl)-l-aspartamide]-camptothecin conjugate? Colloids and Surfaces B: Biointerfaces? 79? 543-549? 2010. Jiahui Yu? Jin Huang? Jaewoon Nah? Myunghaing Cho ? Chongsu Cho*? Degradable poly (ether amine) based on poly (ethylene glycol) dimethacrylate and polyethylenimine as a gene carrier? Journal of Applied Polymer Science? 115, 1189–1198? 2010. Jiahui Yu? Jishan Quan? Jin Huang? Bo Sun? Hulin Jiang? Youkyoung Kim? Jaewoon Nah? Myunghaing Cho? Chongsu Cho? Degradable poly(amino ester) based on poly(ethylene glycol) dimethacrylate and polyethylenimine as a gene carrier: molecular weight of PEI affects transfection efficiency? Journal of Materials Science: Materials in Medicine? 20? 2501-2510? 2009. Jiahui Yu? Chengyun Wang? Jun Hong? Jin Huang*?Resolution of (D? L)-phenylalanine in biphasic system by α-chymotrypsin immobilized on superparamagnetic nanogels? Journal of Macromolecular Science? Part A: Pure and Applied Chemistry? 46? 943-948? 2009. Jiahui Yu? Jishan Quan? Chengxiong Xu? Jin Huang? Chengyun Wang? Bo Sun? Jaewoon Nah? Myunghaing Cho? Chongsu Cho? Fabrication of a novel core-shell gene delivery system based on a brush-like polycation of α? β–poly (L-aspartate-graft-PEI)? Pharmaceutical Research? 26, 2152-63? 2009. Jiahui Yu? Jishan Quan? Jin Huang? Chengyun Wang? Bo Sun? Jaewoon Nah? Myunghaing Cho? Chongsu Cho? α? β–poly (L-aspartate-graft-PEI): a pseudo-branched PEI as a gene carrier with low toxicity and high transfection efficiency? Acta Biomaterialia? 5? 2485–2494? 2009. Yanbao Gong? Mingxia Fan? Feng Gao? Jun Hong? Shunying Liu? Shufang Luo? Jiahui Yu*? Jin Huang? Preparation and characterization of amino-functionalized magnetic nanogels via photopolymerization for MRI applications? Colloids and Surfaces B: Biointerfaces?71?243-247? 2009. Chengyun Wang? Yanbao Gong? Naiqian Fan? Shunying Liu? Shufang Luo? Jiahui Yu*? Jin Huang? Fabrication of polymer-Platinum (II) complex nanomicelle from mPEG-g-α? β-poly [(N-amino acidyl)-DL-aspartamide] and cis-dichlorodiammine Platinum (II) and Its cytotoxicity? Colloids and Surfaces B: Biointerfaces?70? 84-90? 2009. Jiahui Yu? Jin Huang? Hulin Jiang? Jishan Quan? Myunghaing Cho? Chongsu Cho*? Guanidinylated poly (allyl amine) as a gene carrier? Journal of Applied Polymer Science? 112? 926-933? 2009. Jun Hong? Jin Huang? Shunying Liu? Jiahui Yu*? Shufang Luo? Stability and activity of chymotrypsin immobilized on magnetic nanogels covered with carboxyl groups? Journal of Applied Polymer Science? 111? 2844-2850? 2009. Ziyan Zhou? Haitao Huang? Peihu Xu? Lihong Fan? Jiahui Yu*? Jin Huang? Simultaneous enhancement in strength and elongation of polycaprolactone: Role of chitosan-graft- polycaprolactone? Journal of Applied Polymer Science? 112? 692-699? 2009. Jiahui Yu, Fujin Ai, Alain Dufresne, Shanjun Gao, Jin Huang, Peter R. Chang,Structure and mechanical properties of poly(lactic acid) filled with (starch nanocrystal)-graft-poly(ε-caprolactone), Macromolecular Materials and Engineering, 293(9), 763-770, 2008. Jiahui Yu, Guojuan Cui, Ming Wei, Jin Huang, Facile exfoliation of rectorite nanoplatelets in soy protein matrix and reinforced bionanocomposites thereof, Journal of Applied Polymer Science, 104, 3367-3377, 2007. Jiahui Yu, Zhengrong Lu, Hua Zheng and Renxi Zhuo, Synthesis and characterization of new ointment–like poly(ortho esters), European Polymer Journal, 38, 971-975, 2001. Jiahui Yu, Yumin Du and Hua Zheng. Properties and interfacial bonding for regenerated cellulose-polyurethane/amylose acetate SIPN composite films (I), Polymer Composites, 21, 872-877, 2000. Jiahui Yu, Yumin Du and Fangyu Cheng, Study on the properties and interfacial structure between regenerated cellulose film and polyurethane/poly(methyl acrylate) IPN coating, Journal of Macromolecular Science-Pure and Applied Chemistry, 36, 1259-1270, 1999. Chengyun Wang, Yanbao Gong, Shunying Liu, Shufang Luo, Jin Huang, Jiahui Yu*, Synthesis of α, β-poly [(N-succinyl)-l-aspartamide] and in vitro cytotoxicity of its cis-dichlorodiammine platinum macromolecular prodrug, Chemical Journal of Chinese University, 8, 1665-1670, 2008. Jun Li, Feng Qiu, Shufang Luo, Jiahui Yu*, Synthesis and characterization of novel poly (ethylene glycol)-poly (glutamic acid) copolymers, Chemical Engineering and Equipment, 3, 19-20, 2008. Yanbao Gong, Chengyun Wang, Shunying Liu, Shufang Luo, Jiahui Yu*, Shiyuan Liu, Controllable synthesis and characterization of amino-functionalized magnetic nanogels via photopolymerization, Nuclear Techniques, 31,751-755,2008. Jie Shu, Jianqi Li, Min Xu, Shufang Luo, Shunying Liu, Jiahui Yu*, Rong Cong, Bing Du, Preparation and evaluation of liver specific non-ionic polymeric contrast agent, Acta Polymerica Sinica, 2, 116-122,2008. Jie Shu, Min Peng, Jiahui Yu*, Shufang Luo, Lei Yu, Qun Chen, The synthesis of polyacetals and the characterization of its degradation behavior with NMR, Chemical Journal of Chinese University, 28, 1398-1402, 2007. Jiahui Yu*, Shufang Luo, Lei Yu, Qun Chen, New process for preparation of L-lactide by nitrogen bubbling method, Guangdong Chemical Industry, 33, 42-43, 2006. Jiahui Yu, Yumin Du and Hua Zheng. Studies on the preparation, characterization and properties of nylon1010-chitosan blend films, Polymer Materials Science and Engineering, 17, 116-120, 2001. Jiahui Yu, Yumin Du and Hua Zheng. Studies on the preparation, characterization and properties of acetylchitin, Chemistry Acta, 7, 432-434, 2001. Jiahui Yu, Yumin Du and Hua Zheng. Blend films of chitosan-gelatin, Journal of Wuhan University (National Science Edition), 45(4), 440-444, 1999. Coauthor Publications Lei Sun, Jing-e Zhou, Tengshuo Luo, Jing Wang, Liqing Kang, Yeying Wang, Shenggen Luo, Zhehao Wang, Ziyu Zhou, Jiaxi Zhu, Jiahui Yu, Lei Yu, Zhiqiang Yan*, Nanoengineered neutrophils as cellular sonosensitizer for visual sonodynamic therapy of malignant tumors, Advanced Materials, 34, e2109969, 2022. Ying Huang, Lei Wang *, Zhiyang Cheng, Biyu Yang, Jiahui Yu, Yi Chen *, Wei Lu *, SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy,Journal of Controlled Release 339, 297-306, 2021. Shulei Zhu, Yingxin Lu, Jiyu Jin *, Jiahui Yu , Wei Lu *, An HSP90 inhibitor based fluorescent probe for selective tumor targeting, Dyes and Pigments, 196, 109783, 2021. Zhiyang Cheng, Ying Huang, Qianqian Shen, Yangrong Zhao, Lei Wang*, Jiahui Yu, Wei Lu*, A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo, European Journal of Medicinal Chemistry, 226, 113851, 2021. Ying Huang, Hong-bo Ru, Bin Bao, Jiahui Yu, Jia Li, Yi Zang*, Wei Lu*, The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells, Bioorganic & Medicinal Chemistry, 28, 115639, 2020. Ying Huang, Chen Jin, Jiahui Yu, Lei Wang?, Wei Lu?, A novel multifunctional 2-nitroimidazole-based bioreductive linker and its application in hypoxia-activated prodrugs, Bioorganic Chemistry, 101, 103975, 2020. Qiwen Zhu, Bin Bao, Qiumeng Zhang, Jiahui Yu, Wei Lu, Maleimidation of dextran and the application in designing a dextran-camptothecin conjugate, RSC Advances, 5, 2818-2823, 2018. Qiumeng Zhang, Chen Jin, Jiahui Yu, and Wei Lu*, Synthesis of new branched 2-nitroimidazole as a hypoxia sensitive linker for ligand-targeted drugs of paclitaxel, ACS Omega, 3, 8813–8818, 2018. Li Zhan, Shuyuan Chang, Ting Liu, Shanbao Yu, Hui Li, Minjie Lu, Yong Zhu, Yu Luo*, Jiahui Yu, Fan Yang, Jie Tang, A new type of pH-sensitive phospholipid, Tetrahedron Letters 58, 4724-4727, 2017. Chen Jin, Shuai Wen, Qiumeng Zhang, Qiwen Zhu, Jiahui Yu, Wei Lu*, Synthesis and biological evaluation of paclitaxel and camptothecin prodrugs on the basis of 2-nitroimidazole, ACS Medicinal Chemistry Letters, 8, 762–765, 2017. Rui Che, Qiwen Zhu, Jie Yu, Jiao Li, Jiahui Yu, Wei Lu*, Syntheses of two kinds of disaccharide subunits of antitumor antibiotic bleomycins, Tetrahedron, 73, 6172-6180, 2017.? Miao Wu, Feimin Zhang, Jiahui Yu, Hongye Zhou, Di Zhang, Chong Hu, Jin Huang*, Fabrication and evaluation of light-curing nanocomposite resins filled with surface-modified TiO2 nanoparticles for dental application, Iranian Polymer Journal, 23, 513-524, 2014. Junping Zeng, Haitao Huang, Shiyuan Liu, Haibo Xu, Jin Huang*,Jiahui Yu,Hollow nanosphere fabricated from β-cyclodextrin-grafted α, β-poly(aspartic acid) as the carrier of camptothecin, Colloid Surface B: Biointerfaces, 105, 120-127, 2013. Haitao Huang, Xiaolan Zhang, Jiahui Yu, Junping Zeng, Peter R. Chang, Haibo Xu*, Jin Huang*, Fabrication and reduction-sensitive behavior of polyion complex nano-micelles based on PEG-conjugated polymer containing disulfide bonds as a potential carrier of anti-tumor paclitaxel, Colloid Surface B: Biointerfaces, 110, 59-65, 2013. Peter R. Chang, Jingwei Zou, Wulin Shang, Jiahui Yu, Tao Xia, Jin Huang*, Effects of pea protein nanophase on structure and properties of waterborne polyurethane-based composites, Journal of Biobased Materials and Bioenergy, 6, 108-114, 2012. Dengguang Yu*, Jiahui Yu, Lan Chen, Gareth R. Williams, Xia Wang*, Modified coaxial electrospinning for the preparation of high-quality ketoprofen-loaded cellulose acetate nanofibers, Carbohydrate Polymers, 90, 1016-1023, 2012. Junping Zeng, Jiahui Yu, Jin Huang*, Peter R. Chang*, Self-assembled polymeric nanomicelles as delivery carriers for anti-tumor drug camptothecin, Journal of Dispersion Science And Technology, 33, 293-306 (Review), 2012. Zhongshi Liang, Yun Liu, Xiangyang Li, Qinge Wu, Jiahui Yu, Shufang Luo, Lihui Lai, Shunying Liu*, Surface-modified gold nanoshells for enhanced cellular uptake, J Biomed Mater Res Part A, 98A:479–487, 2011. Jingwei Zou, Fang Zhang, Jin Huang*, Peter R Chang*, Zhongmin Su, Jiahui Yu, Effects of starch nanocrystal on structure and properties of waterborne polyurethane-based composites, Carbohydr. Polym., 85, 824-831, 2011. Ning Lin, Jin Huang*, Peter R. Chang*, Jiwen Feng, Jiahui Yu, Surface Acetylation of Cellulose Nanocrystal and Its Reinforcing Function in Poly(lactic acid), Carbohydr. Polym., 83, 1834-1842, 2011. Ning Lin, Jin Huang*, Peter R. Chang*, Liangdong Feng, Jiahui Yu, Effect of Polysaccharide Nanocrystals on Structure, Properties and Drug Release Kinetics of Alginate-Based Microspheres, Colloid Surface B: Biointerfaces, 85, 270-279, 2011. Ning Lin, Dongkuan Fan, Peter R. Chang*, Jiahui Yu, Xiaochun Cheng, Jin Huang*, Structure and Properties of Poly (Butylene Succinate) Filled with Lignin: A Case of Lignosulphonate, J. Appl. Polym. Sci., 121, 1717-1724, 2011. Jin Huang, Jingwei Zou, Peter R. Chang*, Jiahui Yu, Alain Dufresne, New Waterborne Polyurethane-Based Nanocomposites Reinforced with Low Loading Levels of Chitin Whisker, Express Polym. Lett., 5, 362-373, 2011. Ning Lin, Jiahui Yu, Peter R. Chang*, Junli Li, Jin Huang*, Poly(Butylene Succinate)-Based Biocomposites Filled with Polysaccharide Nanocrystals: Structure and Properties, Polym. Compos., 32, 472-482, 2011. Dongkuan Fan, Peter R. Chang, Ning Lin, Jiahui Yu, Jin Huang*, Structure and Properties of Alkaline Lignin Filled Poly (Butylene Succinate) Plastics, Iranian Polym. J., 20, 3-14, 2011. Ning Lin, Jin Huang*, Peter R. Chang*, Debbie P. Anderson, Jiahui Yu, Preparation, Modification, and Application of Starch Nanocrystals in Nanomaterials: A Review, J. Nanomater., 5, 736-87 (Invited Review), 2011. Honglin Chen, Xianqun Fan, Jing Xia, Ping Chen, Xiaojian Zhou, Jin Huang, Jiahui Yu, Ping Gu*, Electrospun chitosan-graft-poly (ε-caprolactone)/poly (ε-caprolactone) nanofibrous scaffolds for retinal tissue engineering, International Journal of Nanomedicine, 6, 453–461, 2011. Xiaolan Zhang, Jin Huang*, Peter R. Chang*, Junli Li, Yongming Chen, Daxin Wang, Jiahui Yu, Jinghua Chen, Structure and Properties of Polysaccharide Nanocrystal-Doped Supramolecular Hydrogels Based on Cyclodextrin Inclusion, Polymer, 51, 4398-4407, 2010. Peihu Xu, Fengfeng Guo, Jin Huang*, Shaofeng Zhou, Daxin Wang*, Jiahui Yu, Jinghua Chen, Alginate-Based Ferrofluid and Magnetic Microsphere Thereof, Int. J. Biol. Macromol., 47, 654-660, 2010. Zhongying Hui, Xiaolan Zhang, Jiahui Yu, Jin Huang*, Zhongshi Liang, Daxin Wang*, Haitao Huang, Peihu Xu, Carbon Nanotube-Hybridized Supramolecular Hydrogel Based on PEO-b-PPO-b-PEO / a-Cyclodextrin as A Potential Biomaterial, J. Appl. Polym. Sci., 116, 1894-1901, 2010. Shunying Liu, Zhongshi Liang, Shuyan Zhang, Feng Gao, Jiahui Yu, Shufang Luo*, The synthesis of silica nanoparticles with precise particle size control via modified St?ber method, Journal of East China Normal University (Natural Science Edition), 2, 112-121, 2009. Shunying Liu, Zhongshi Liang, Feng Gao, Jiahui Yu, Shufang Luo*, Jesus N. Calata, Guoquan Lu, A Facile Approach to the Synthesis of Gold Nanoshells with Near Infrared Responsive Properties, Chinese Journal of Chemistry, 6, 1079-1085, 2009. Hu-Lin Jiang, You-Kyoung Kim, Rohidas Arote, Dhananjay Jere, Ji-Shan Quan, Jia-Hui Yu, Yun-Jaie Choi, Jae-Woon Nah, Myung-Haing Cho, Chong-Su Cho* Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting,International Journal of Pharmaceutics, 375, 133-139, 2009. Jun Hong, Dongmei Xu, Peijun Gong, Jiahui Yu, Hongjuan Ma, Side Yao*. Covalent-bonded immobilization of enzyme on hydrophilic polymer covering magnetic nanogels. Microporous and Mesoporous Materials, 109, 470–477, 2008. Huijing Han, Fengxiang Chen, Jiahui Yu, Jingya Dang, Zhuo Ma, Yiqun Zhang, Meiran Xie*, Ring-opening metathesis polymerization of functionalized cyclooctene by a ruthenium-based catalyst in ionic liquid, J. Polym. Sci. Part A: Polym Chem, 45, 3986-3993, 2007. Jun Hong, Pei Jun Gong, Jiahui Yu, Dong Mei Xu, Han Wen Sun, Side Yao*. Conjugation of α-chymotrypsin on a polymeric hydrophilic nanolayer covering magnetic nanoparticles. Journal of Molecular Catalysis B: Enzymatic, 42, 99–105, 2006. Hanwen Sun, Jun Hong, Fanzong Meng, Peijun Gong, Jiahui Yu, Yanling Xue, Sufang Zhao, Dongmei Xu, Li Dong and Side Yao*. Novel core-shell structure polyacrylamide-coated magnetic nanoparticles synthesized via photochemical polymerization. Surface and Coatings Technology, 201, 250–254, 2006. Peijun Gong, Jiahui Yu, Hanwen Sun, Jun Hong, Sufang Zhao, Dongmei Xu, Side Yao*,Preparation and Characterization of OH-Functionalized Magnetic Nanogels under UV Irradiation,Journal of Applied Polymer Science, 101, 1283–1290, 2006. Dongmei Xu, Jiahui Yu, Yongbiao Liu, Hanwen Sun, Jingying Xu, Kanglong Sheng, Side Yao*, Yuhong Xu, Huili Lu, Novel polyethylenimine nanogels as potential gene carriers produced via photochemistry in surfactant-free aqueous solution, International Journal of Nanoscience, 5(6), 753-756, 2006. Hanwen Sun, Jiahui Yu, Gongpei Gong, Dongmei Xu, Jun Hong, Chunfu Zhang, Side Yao*, Novel core-shell magnetic nanogels synthesized in an emulsion- free qusous system under Uv irradiation for potential targeted radiopharmaceutical applications, International Journal of Nanoscience, 5(2/3), 253-258, 2006. Hanwen Sun, Jiahui Yu, Peijun Gong, Dongmei Xu, Chunfu Zhang, Side Yao*.Novel core-shell magnetic nanogels synthesized in an emulsion-free aqueous system under UV irradiation for targeted radiopharmaceutical applications. Journal of magnetism and magnetic materials, 294 (3): 273-280, 2005. Hanwen Sun, Jiahui Yu, Dongmei Xu, Peijun Gong, Jun Hong, Chunfu Zhang, Side Yao*. Core-shell magnetic nanogels synthesis in aqueous solution via surfactant free photochemical reaction. Journal of Radiation Research and Radiation Processing, 23(4): 193-195, 2005. Hua Zheng, Yumin Du*, Jiahui Yu, Ronghua Huang, Lina Zhang. Preparation and Characterization of Chitosan/Poly(vinyl alcohol) Blend Fibers, Journal of Applied Polymer Science, 80(13), 2558-2565, 2001. Zhengrong Lu*, Jiahui Yu, Renxi Zhuo. Synthesis of New Ointment-like Poly (ortho esters), Chinese Chemical Letters, 8(2), 114-116, 1997. Weiwei Men, Na Li, Jiahui Yu, Shufang Luo, Jianqi Li, Mingxia Fan*. Accurate depicting metabolic process of macromolecule gadolinium magnetic resonance contrast agent, Chin J Interv Imaging Ther, 7(3), 320-324, 2010. Zhongshi Liang, Kongrong Duan, Yanyun Liu, Yun Liu, Jiahui Yu, Shunying Liu*. The study of the structure influence of surface-modified gold/silica nanoshells with the small functional molecules, Functional Materials, 9(41), 1511-1515, 2010. Peijun Gong, Shufang Zhao, Jun Hong, Side Yao*, Jiahui Yu, Liangchao Li, Photo chemical preparation of Au/Fe3O4 magnetic composite particles, Journal of Radiation Research and Radiation Processing, 26(2),108-111,2008. Jun Hong, Dongmei Xu, Peijun Gong, Jiahui Yu, Hanwen Sun, Side Yao*, Synthesis of particle size controllable carboxyl-functionalized magnetic nanogels, Journal of Radiation Research and Radiation Processing, 24(5): 280-282, 2006. Peiju Gong, Jun Hong, Xinfeng Liu, Jiahui Yu, Chunhai Fan, Li Dong, Side Yao*, Preparation of amine based magnetic nanogels with amino groups for streptavidin immobilization by photochemistry, Journal of Radiation Research and Radiation Processing, 24(6),345-350,2006. Hanwen Sun, Jiahui Yu, Chunfu Zhang, Leidong Xie, Zhengchi Hou, Dongmei Xu, Side Yao*, Preparation and characterization of Fe3O4 magnetic nano?particles modified with poly(N?isopropylacrylamide)by UV irradiation Journal of Radiation Research and Radiation Processing, 22(5): 293-296, 2004. Hua Zheng, Yumin Du*, Jiahui Yu, Ling Xiao. The Properties and Preparation of Crosslinked Chitosan Films, Chemical Journal of Chinese Universities, 21(5), 809-812, 2000. Hua Zheng, Yumin Du*, Jiahui Yu, Ling Xiao. Studies on the Preparation and Controlled Degree of Substitute for N- acylchitosan, Journal of Wuhan University (National Science Edition), 46(6), 685-688, 2000. Hua Zheng, Yumin Du*, Jiahui Yu. Structure and Preparation of Chitosan/Poly(vinyl alcohol) Blend Fibers, Journal of Wuhan University (National Science Edition), 46(2), 187-190, 2000. Zhengrong Lu*, Jiahui Yu, Renxi Zhuo, Xuli Wang, Fuhua Yang. Studies on the Preparation and in vitro Cytotoxicity of Poly (L-aspartic acid) Derivatives-cis-platin Conjugates, Chemical Journal of Chinese Universities, 19(5), 817-820, 1998.

学术兼职

中国生物医学工程学会纳米医学与工程分会 委员 上海市生物医学工程学会放射医学工程专委会 委员 中国微米纳米技术学会纳米科学技术分会会员 中国生物材料学会会员 中国化学学会员

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