罗潇 - 华东师范大学 - 化学与分子工程学院

个人简介

教育经历 2009.09-2013.06 华东理工大学制药工程工学学士 2013.09-2018.06 华东理工大学药药学学医学博士（导师：杨有军教授）工作经历 2018.06-2021.08 华东师范大学化学与分子工程学院博士后（导师：钱旭红院士） 2021.09-至今1 华东师范大学化学与分子工程学院紫江青年研究员（博导、硕导）

研究领域

生物氧化还原的化学精准调控 1）开发活性氧探针——实现活性氧的高时空分辨原位监测——绘制生物氧化还原网络； 2）开发活性氧供体——实现活性氧的原位、精准控制释放——解析生物氧化还原机制； 3）创制活性氧淬灭剂——实现活性氧的高效、靶向清除——开发抗氧化损伤新型化学实体

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Xiaohua Chen†, Jiamin Liu†, Ming Chen†, Jie Zhou, Yuyang Zhang, Xinru Hu, Weixi Geng, Qiyue Mao, Hiroaki Kitagishi, Jinquan Chen, Xuhong Qian*, Youjun Yang*, Yuan Lei*, Xiao Luo*. Green-Light-Triggered and Self-Calibrated Cascade Release of Nitric Oxide and Carbon Monoxide for Synergistic Glaucoma Therapy. J. Am. Chem. Soc. 2024, 146, 30361−30371. Xin-Jian Guo, Lin-Yan Huang, Shi-Tong Gong, Ming Li, Wan Wang, Jie Chen, Yi-De Zhang, Xicun Lu, Xiaohua Chen, Lan Luo, Youjun Yang, Xiao Luo*, Su-Hua Qi*. Peroxynitrite-Triggered Carbon Monoxide Donor Improves Ischemic Stroke Outcome by Inhibiting Neuronal Apoptosis and Ferroptosis. Mol. Neurobiol. 2024, doi.org/10.1007/s12035-024-04238-w. Lei Yin#, Bei Zhao#, Jie Zhou#, Yunxia Huang, Hao Ma, Ting Zhou, Jie Mou, Peiru Min*, Jinquan Chen*, Guangbo Ge*, Xuhong Qian*, Xiao Luo*, Youjun Yang*. A Carbon-Caged Rhodamine Generating Nitrosoperoxycarbonate for Photoimmunotherapy. Angew. Chem. Int. Ed. 2024, 202402949. Xiao Luo?*, Zhonghui Zhang?, Jie Wang?, Xueli Wang, Yani Zhang, Jinquan Chen, Guangbo Ge, Wen Yang*, Xuhong Qian*, Yang Tian*, Youjun Yang*. Acyl-Caged Rhodamines: Photo-Controlled and Self-Calibrated Generation of Acetyl Radical for Neural Function Recovery in Early AD Mouse. Chem. Sci. 2023, 14, 11689. Jinyan Zhang, Liwei Liu, Zhen Dong, Xicun Lu, Wenxuan Hong, Jin Liu, Xiaoyi Zou, Jinfeng Gao, Hao Jiang, Xiaolei Sun, Kai Hu, Youjun Yang, Junbo Ge, Xiao Luo*, Aijun Sun*. An ischemic area-targeting, peroxynitrite-responsive, biomimetic carbon monoxide nanogenerator for preventing myocardial ischemia-reperfusion injury. Bioact. Mater. 2023, 28, 480–494. Yinghua Guo, Lei Yin, Xuhong Qian, Youjun Yang*, Xiao Luo*. PET/d-PET (PdP) Pairing for the Design of Dual-Channel Probes. Anal. Chem. 2023, 95, 9722–9728. Shuhuai Shen, Youjun Yang, Xiao Luo*, Xuhong Qian. Hill?type pH probes. Anal. Bioanal. Chem. 2023, 415, 3693-3702. Zhenzhen Lin, Fang Hu, Gang He*, Youjun Yang, Yujun Liao, Xiao Luo*, Xu-Dong Wang*. Highly Photostable and pH- Sensitive Nanosensors. Chemosensors 2022, 10, 354. Linfeng Xing#, Bin Wang#, Jin Li#, Xinjian Guo, Xicun Lu, Xiaohua Chen, Haitao Sun, Zhenrong Sun, Xiao Luo*, Suhua Qi*, Xuhong Qian*, Youjun Yang*. A Fluorogenic ONOO--Triggered Carbon Monoxide Donor for Mitigating Brain Ischemic Damage. J. Am. Chem. Soc. 2022, 144, 2114-2119. Yansheng Xiao, Yunxia Huang, Zhenhua Zeng, Xiao Luo*, Xuhong Qian, Youjun Yang*. “Harnessing Thorpe–Ingold Dialkylation to Access High-Hill-Percentage pH Probes.” J. Org. Chem. 2022, 87, 85-93. Yang Yu, Xiaodong Zhang, Yan Dong, Xiao Luo*, Xuhong Qian, Youjun Yang*. “Fusing the Nagano’s and the Anslyn’s chemistry for lyso-specifc NO detection.” Sens. Actuators B Chem. 2021, 346, 130562. Fang Hu, Yunxia Huang, Yansheng Xiao, Yanchun Li, Xiao Luo*, Xuhong Qian, Youjun Yang*. “A dual-channel Hill-type small-molecule pH probe.” Anal. Methods 2021, 13, 3012–3016. Jin Li, Mengmeng Zhang, Lu Yang, Yubing Han, Xiao Luo*, Xuhong Qian*, YoujunYang*. “‘Xanthene’ is a premium bridging group for xanthenoid dyes.” Chin. Chem. Lett. 2021, 32, 3865-3869. Rui Yan#, Xiao Luo#, Jinfeng Zhou, Ping Wang, Youjun Yang*, Xuhong Qian, Yueling Liu*. “Biodegradable ion-selective nanosensors with p-diethylaminophenol functionalized rhodamine as chromoionophore for metal ions measurements.” Sens. Actuators B Chem. 2021, 336, 129672 Yansheng Xiao, Yanchun Li, Fang Hu, Kang-nan Wang, Zong-wan Mao, Xiao Luo*, Zhenglong Sun*, Xuhong Qian, Youjun Yang*. “A nucleolus-targeting Hill-type pH probe.” Sens. Actuators B Chem. 2021, 335, 129712. Xiu Xu#, Meiling Sun#, Xiao Luo#, Ziqian Zhang, Lin Su, Lingfei Cui, Zhihui Zhu, Xicun Lu, Rui Wang, Feng Han*, Xuhong Qian, Youjun Yang*. “One-electron reduction triggered nitric oxide release for ischemia-reperfusion protection”. Free Radical Biol. Med. 2021, 164, 13-19. Yansheng Xiao, Fang Hu, Xiao Luo*, Mingming Zhao, Zhenglong Sun*, Xuhong Qian*, Youjun Yang*. “Modulating the pKa Values of Hill-Type pH Probes for Biorelevant Acidic pH Range”. ACS Appl. Bio Mater. 2020, 4, 2097-2103. Ziqian Zhang, Xiao Luo, Youjun Yang*. “From Spontaneous to Photo-triggered and Photo-calibrated Nitric Oxide Donors”. Isr. J. Chem. 2021, 61, 159-168. Kai Xin#, Xinxing Li#, Yinghua Guo#, Youhuan Zhong#, Jungang Wang, Haotian Yang, Jie Zhao, Chunlei Guo, Yunxia Huang, Zuhai Lei, Yi-Lun Ying, Xiao Luo*, Haolu Wang, Xuhong Qian, Wen Yang*, Xiaowen Liang*, Youjun Yang*. “A Mono-Chromophoric Approach to Succinct Ratiometric Fluorescent Probes without Probe-Product Crosstalk.” CCS Chem. 2020, 2, 2307–2315. Xiao Luo, Yan Chen, Yanchun Li, Zhenglong Sun*, Weihong Zhu*, Xuhong Qian*, Youjun Yang*, “Structurally-thrifty and visible-absorbing fluorophores.” Spectrochimica Acta Part A 2021, 245, 118907 Luyan Gu#, Lujia Zhang#, Xiao Luo*, Ying Zheng, Zhiwei Ye, Meng Lv, Jinquan Chen, Chunlai Chen*, Yi Xiao, Weihong Zhu, Xuhong Qian, Youjun Yang*. “The Mechano Donor-Acceptor Coupling (MDAC) Approach for Uni-directional Multi-State Fluorochromism.” Sci China: Chem. 2020, 64, 253-262. Xiao Luo, Youjun Yang*, Xuhong Qian*. “Recent progresses on the development of thioxo-naphthalimides.” Chin. Chem. Lett. 2020, 31, 2877-2883. Xiao Luo, Luyan Gu, Xuhong Qian, Youjun Yang*. “Molecular probe design via the ‘covalent-assembly’ principle.” Chem. Commun. 2020, 56, 9067-9078. Xiao Luo, Jin Li, Jie Zhao, Luyan Gu, Xuhong Qian*, Youjun Yang*. “A General Approach to the Design of High-Performance Near-Infrared (NIR) D-p-A Type Fluorescent Dyes.” Chin. Chem. Lett. 2019, 30, 839-846. Xiao Luo#, Liujia Qian#, Yansheng Xiao, Yao Tang, Yang Zhao, Xia Wang, Luyan Gu, Zuhai Lei, Jianming Bao, Jiahui Wu, Tingting He, Fupin Hu, Jing Zheng, Honglin Li, Weiping Zhu, Lei Shao, Xiaojing Dong, Daijie Chen*, Xuhong Qian*, Youjun Yang*. “A Diversity-Oriented Rhodamine Library for Wide-Spectrum Bactericidal Agents with Low Inducible Resistance against Resistant Pathogens.” Nat. Commun. 2019, 10, 258. Xiao Luo, Haotian Yang, Haolu Wang, Zhiwei Ye, Zhongneng Zhou, Luyan Gu, Jinquan Chen, Yi Xiao, Xiaowen Liang*, Xuhong Qian, Youjun Yang*. “Highly Sensitive Hill-Type Small-Molecule pH Probe That Recognizes the Reversed pH Gradient of Cancer Cells.” Anal. Chem. 2018, 90, 5803–5809.