个人简介
教育背景
2010-01--2011-03 加拿大渥太华大学 联合培养
2005-09--2011-07 中国科学院大连化学物理研究所 理学博士
2001-09--2005-07 浙江大学化学系 理学学士
工作简历
2011-10--今 中国科学院大连化学物理研究所 副研究员、研究员
研究领域
复杂生物样品高分辨分离分析
修饰蛋白质高灵敏度检测
蛋白质周转分析
近期论文
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Highly efficient N-glycoproteomic sample preparation by combining C(18) and graphitized carbon adsorbents,Analytical and Bioanalytical Chemistry,2014,通讯作者
Large-scale proteome quantification of hepatocellular carcinoma tissues by a three-dimensional liquid chromatography strategy integrated with sample preparation,Journal of Proteome Research ,2014,通讯作者
Comprehensive mapping of protein N-glycosylation in human liver by combining hydrophilic interaction chromatography and hydrazide chemistry,Journal of Proteome Research,2014,通讯作者
Five-plex isotope dimethyl labeling for quantitative proteomics,Chemical Communications,2014,通讯作者
Monolithic capillary column based glycoproteomic reactor for high-sensitive analysis of N-glycoproteome,Analytical Chemistry,2013,通讯作者
Phosphoproteome analysis of an early onset mouse model TgCRND8 of Alzheimers disease reveals temporal changes in neuronal and glia signaling pathways,Proteomics,2013,第1作者
Separation of intact proteins by using polyhedral oligomeric silsesquioxane based hybrid monolithic capillary columns,Journal of Chromatography A,2013,通讯作者
A six-plex proteome quantification strategy reveals the dynamics of protein turnover,Scientific Reports,2013,第1作者
Preparation of capillary hybrid monolithic column with sulfonate strong cation exchanger for proteome analysis,Journal of Chromatography A,2012,第1作者
Comprehensive analysis of the N and C terminus of endogenous serum peptides reveals a highly conserved cleavage site pattern derived from proteolytic enzymes,Protein Cell,2012,第1作者
Combination of online enzyme digestion with stable isotope labeling for high-throughput quantitative proteome analysis,Proteomics,2012,第1作者
Perspectives of comprehensive phosphoproteome analysis using shotgun strategy,Analytical Chemistry ,2011,第1作者
Improvement of the quantification accuracy and throughput for phosphoproteome analysis by a pseudo triplex stable isotope dimethyl labeling approach,Analytical Chemistry ,2011,第1作者
A fully automated system with online sample loading, isotope dimethyl labeling and multidimensional separation for high-throughput quantitative proteome analysis,Analytical Chemistry ,2010,第1作者
Online multidimensional separation with biphasic monolithic capillary column for shotgun proteome analysis,Journal of Proteome Research ,2008,第1作者
Capillary trap column with strong cation-exchange monolith for automated shotgun proteome analysis,Analytical Chemistry ,2007,第1作者