Itami, Kenichiro - Nagoya University - Department of Chemistry, Graduate School of Science

个人简介

Education 1990~1994 B.S. in Chemistry, Kyoto University, JapanAdvisor: Prof. Hisanobu Ogoshi 1994~1996 M.S. Graduate Student in Chemistry, Kyoto University, JapanAdvisor: Prof. Yoshihiko Ito 1996~1998 Ph.D. Graduate Student in Chemistry, Kyoto University, JapanAdvisor: Prof. Yoshihiko Ito 1996~1998 JSPS Research Fellowship for Young Scientists 1997~1998 Exchange Student, Uppsala University, Sweden (Prof. Jan-E. Bäckvall) Academic Career 1998~2005 Assistant Professor, Kyoto University (with Prof. Jun-ichi Yoshida) 2005~2008 Associate Professor, Nagoya University (with Prof. Ryoji Noyori) 2005~2009 JST, PRESTO, Researcher 2008~present Professor, Department of Chemistry, Graduate School of Science, Nagoya University 2012~present Director and PI, Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University 2013~2020 Research Director, JST, ERATO, Itami Molecular Nanocarbon Project 2019~present Joint Appointment Research Fellow, Institute of Chemistry, Academia Sinica, Taiwan

研究领域

The main emphasis of his research is on the development of new synthetic methods, strategies, and concepts to solve challenging synthetic problems for realizing ideal chemical synthesis and for generating as-yet unexplored molecules of significant interest. Representative projects include (1) ideal chemical synthesis through C-H bond transformation, (2) rapid synthesis of pharmaceutically relevant molecules and natural products, (3) synthesis and properties of optoelectronic materials, and (4) controlled bottom-up synthesis of structurally uniform nanocarbons such as carbon nanotubes, graphenes, and fullerenes.

近期论文

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Perfluorocycloparaphenylenes: Fully fluorinated carbon nanorings by Ni-mediated one-pot synthesis Hiroki Shudo, Motonobu Kuwayama, Masafumi Shimasaki, Taishi Nishihara, Youhei Takeda, Takuya Kuwabara, Akiko Yagi, Yasutomo Segawa, Kenichiro Itami Submitted. ChemRxiv, DOI 10.33774/chemrxiv-2021-7kd63 Molecular nanocarbons add new dimensions to organic chemistry Kenichiro Itami, Takehisa Maekawa J. Org. Chem. 2021, 86, in press. Org. Lett. 2021, 23, in press. Infinitene: A Helically Twisted Figure-Eight [12]Circulene Topoisomer Maciej Krzeszewski, Hideto Ito,* Kenichiro Itami* Submitted. ChemRxiv DOI: 10.33774/chemrxiv-2021-pcwcc [link] [detail] Stepwise Generation of Mono-, Di-, and Triply-Reduced Warped Nanographenes: Charge-Dependent Aromaticity, Surface Nonequivalence, Swing Distortion and Metal Binding Sites Sarah N. Spisak, Zheng Zhou, Shuyang Liu, Qi Xu, Zheng Wei, Kenta Kato, Yasutomo Segawa, Kenichiro Itami, Andrey Yu. Rogachev, Marina A. Petrukhina* Chemical Synthesis of Carbon Nanorings and Nanobelts Yuanming Li, Hideya Kono, Takehisa Maekawa, Yasutomo Segawa, Akiko Yagi, Kenichiro Itami Acc. Mater. Res. 2021, ASAP. Diversity-oriented synthesis of nanographenes enabled by dearomative annulative π-extension Wataru Matsuoka, Hideto Ito,* David Sarlah,* Kenichiro Itami* Nature Communication, 2021, 12, 3940. DOI: 10.1038/s41467-021-24261-y [detail] Synthesis and properties of helically-folded poly(arylenediethynylene)s Michihisa Toya, Hideto Ito,* Kenichiro Itami* Polymer Chemistry, 2021,12, 3290–3298. [detail] DOI: 10.1039/D1PY00144B Photoredox-catalyzed benzylic esterification via radical-polar crossover Bumpei Maeda, Yota Sakakibara, Kei Murakami, Kenichiro Itami Org. Lett. 2021, accepted Reversible modulation of circadian time with chronophotopharmacology Dušan Kolarski, Carla Miró-Vinyals, Akiko Sugiyama, Ashutosh Srivastava, Daisuke Ono, Yoshiko Nagai, Mui Iida, Kenichiro Itami, Florence Tama, Wiktor Szymanski, Tsuyoshi Hirota, Ben L. Feringa Nature Commun. 2021, 12, 3164. DOI: 10.1038/s41467-021-23301-x Photo-induced arylation of carbazoles with aryldiazonium salts Bumpei Maeda, Genki Mori, Yota Sakakibara, Akiko Yagi, Kei Murakami, Kenichiro Itami Asian J. Org. Chem. 2021, Accepted Article. Synthesis of a zigzag carbon nanobelt Kwan Yin Cheung, Kosuke Watanabe, Yasutomo Segawa, Kenichiro Itami Nature Chem. 2021, 13, 255-259. ChemRxiv, DOI 10.26434/chemrxiv.12324353.v2. Highlighted in many media worldwidely. Construction of Heptagon-Containing Molecular Nanocarbons Chaolumen, Iain A. Stepek, Keigo E. Yamada, Hideto Ito,* Kenichiro Itami* Angew. Chem. Int. Ed., 2021, 60, XXXX. https://doi.org/10.1002/anie.202100260 [detail] Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock Dušan Kolarski, Simon Miller, Tsuyoshi Oshima, Yoshiko Nagai, Yugo Aoki, Piermichele Kobauri, Ashutosh Srivastava, Akiko Sugiyama, Kazuma Amaike, Ayato Sato, Florence Tama, Wiktor Szymanski, Ben Feringa, Kenichiro Itami, Tsuyoshi Hirota J. Am. Chem. Soc. 2021, 143, 4, 2078. Double-helix supramolecular nanofibers assembled from negatively curved nanographenes Kenta Kato, Kiyofumi Takaba, Saori Maki-Yonekura, Nobuhiko Mitoma, Yusuke Nakanishi, Taishi Nishihara, Taito Hatakeyama, Takuma Kawada, Yuh Hijikata, Jenny Pirillo, Lawrence T. Scott, Koji Yonekura, Yasutomo Segawa, Kenichiro Itami ChemRxiv 2020, DOI: 10.26434/chemrxiv.13270607.v1 Development of potent inhibitors for strigolactone receptor DWARF 14 Masahiko Yoshimura, Sojung F. Kim, Ryosuke Takise, Shuhei Kusano, Sakuya Nakamura, Masanori Izumi, Akiko Yagi, Kenichiro Itami, Shinya Hagihara Chem. Commun. 2020, DOI: 10.1039/d0cc01989e A theoretical study on the strain energy of helicene-containing carbon nanobelts Kosuke Watanabe, Yasutomo Segawa,* and Kenichiro Itami* Chem. Commun. 2020, DOI: 10.1039/D0CC06373H Small Molecules Modulating Mammalian Biological Clocks: Exciting New Opportunities for Synthetic Chemistry Kazuma Amaike, Tsuyoshi Oshima, Nicola Stephanie Skoulding, Yoshifumi Toyama, Tsuyoshi Hirota, Kenichiro Itami Chem, 2020, in press. A N-terminally deleted form of the CK2a’ catalytic subunit is sufficient to support cell viability Christian Borgo, Claudio D’Amore, Luca Cesaro, Kenichiro Itami, Tsuyoshi Hirota, Lorenzo A. Pinna, Mauro Salvi Biochem. Biophys. Res. Commun. 2020, in press. Key ingredients for a successful academic research institute Wolf B. Frommer, Kenichiro Itami EMBO Reports, 2020, in press. Creation of negatively curved polyaromatics enabled by annulative coupling that forms an eight-membered ring. Satoshi Matsubara, Yoshito Koga, Yasutomo Segawa, Kei Murakami, Kenichiro Itami Nature Catal. 2020, accepted. DOI: 10.1038/s41929-020-0487-0